Velarion · Company Intelligence
CompBrief
Fiscal year 2025

E. Rand Sutherland — FY2025 total compensation $4,302,100

E. Rand Sutherland is Chief Executive Officer of Upstream Bio, Inc. (UPB). The company reported total compensation of $4,302,100 for fiscal year 2025.

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Fiscal year 2025 compensation

Salary$650,000
Bonus$0
Stock awards$0
Option awards$3,300,350
Non-equity incentive plan$341,250
Pension and non-qualified deferred compensation$0
All other compensation$10,500
Total$4,302,100

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed, without adjustment.

Cited to the compensation disclosure Upstream Bio, Inc. filed April 16, 2026, accession 0001193125-26-158966.

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History — every fiscal year held

Fiscal yearRoleSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
FY2025Chief Executive Officer$650,000$0$0$3,300,350$341,250$0$10,500$4,302,100
FY2024Chief Executive Officer$407,955$8,375,648$315,000$10,350$9,108,953

Totals as disclosed in each year's own compensation disclosure for Upstream Bio, Inc..

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The other named executive officers of Upstream Bio, Inc.

Named executive officerRoleFY2025 total
E. Rand Sutherland this pageChief Executive Officer$4,302,100
Michael Paul GrayChief Financial Officer and Chief Operating Officer$1,993,437
Aaron DeykinChief Medical Officer and Head of Research and Development$1,830,916

The company's named executive officers for fiscal year 2025, and what it reported for each. See the full Upstream Bio, Inc. compensation brief.

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The company page

E. Rand Sutherland's compensation sits inside Upstream Bio, Inc.'s full executive and board picture — the peer group, pay against peers, incentive design and the board itself.

The Upstream Bio, Inc. (UPB) compensation brief