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Companies Spero Therapeutics, Inc.

Spero Therapeutics (SPRO): executive pay, fiscal 2025

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CEO total pay$2,061,496CEO Esther Rajavelu · source
Say-on-pay support96.53%Latest vote · source

CEO pay, last three years

  • $856,479FY2024
  • $2,061,496FY2025

CEO total pay was $2,061,496 in fiscal 2025, up from $856,479 in fiscal 2024.

FY2025: salary $577,179 · bonus $687,479 · stock awards $413,705 · option awards $0

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Full detail

Every table from the filing. Open any section.

Summary compensation table
Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Esther Rajavelu$577,179$687,479$413,705$0$372,000$0$11,134$2,061,496
President and Chief Executive Officer, Chief Financial Officer, Chief Business Officer and Treasurer(5)
Satyavrat Shukla244,153452,813603,3800307,9120416,9192,025,178
Former President and Chief Executive Officer(6)
Tim Keutzer484,566498,818213,7100232,592011,1341,440,820
Chief Operating Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Esther Rajavelu$2,061,496$856,479—↑ +1,205,017
Satyavrat Shukla2,025,1781,953,2372,024,647↑ +71,941
Tim Keutzer1,440,8201,033,450—↑ +407,370

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

Incentive-plan design — the Compensation Discussion & Analysis

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultantMeridian Compensation Partners, LLC
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingfalse
Equity grants and outstanding awards

No plan-based awards are on file for this fiscal year.

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Tim KeutzerOption2,21611.18—
Tim KeutzerRSU9,503—22,142
Esther RajaveluRSU89,899—209,465
Tim KeutzerRSU132,978—309,839
Esther RajaveluRSU150,000—349,500
Tim KeutzerRSU179,798—418,929
Esther RajaveluRSU185,000—431,050
Tim KeutzerRSU266,139—620,104
Esther RajaveluRSU366,139—853,104
Director compensation
DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
John C. Pottage Jr., M.DNot independent · Development (Chair)$50,000$57,800——$225,000$332,800
Frank E. ThomasIndependent · Board Chair130,00057,800——0187,800
Patrick Vink, M.DIndependent · Nominating and Corporate Governance (Chair) · Compensation83,75057,800——0141,550
Milind Deshpande, Ph.DIndependent · Audit · Nominating and Corporate Governance · Development62,50057,800——0120,300
Cynthia SmithIndependent · Compensation (Chair)60,00057,800——0117,800
Scott JacksonIndependent · Audit · Nominating and Corporate Governance57,50057,800——0115,300
Kathleen TregoningIndependent · Compensation50,00057,800——0107,800
Ankit Mahadevia, M.DNot independent · Development45,00057,800——0102,800
Esther RajaveluEmployee director—————0

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer$20,000
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)20,000 / 20,000 / 15,000
Stock ownership guideline—

Total cost of the board

ComponentFY2025
Cash retainers and fees$538,750
Equity awards (grant-date value)$462,400
All other compensation$225,000
Total cost of the board$1,226,150

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

Peer group, and who names Spero Therapeutics as a peer

Companies that benchmark against SPRO

1 company names SPRO as a compensation peer

The list of companies that name SPRO as a peer is temporarily unavailable — recheck shortly.

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company’s own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Spero Therapeutics, Inc.2025Esther Rajavelu$577,179$413,705$0$372,000$2,061,496

Each peer’s compensation is from its most recently filed proxy; fiscal years differ by company. Each peer’s figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

Say-on-pay history and pay ratio
Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-06-2327,890,2541,002,982107,17496.53%Passed
20252025-06-1225,178,672638,744354,78497.53%Passed
20242024-05-2923,890,281442,014404,37198.18%Passed
20232023-10-0520,123,6471,145,027259,28594.62%Passed
20222022-09-15—————
20212021-08-17—————

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year’s compensation.

Say-on-pay — history, company’s computation

Meeting yearMeeting dateApproval — company’s computation
20262026-06-2396.53%a
20252025-06-1297.53%b
20242024-05-2998.18%c

a. Voting standard not stated in the filing.

b. Voting standard not stated in the filing.

c. Approved under the standard stated in the filing — “Abstentions will have no effect on the results of this vote.”.

Approval percentages are the company’s own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

Insider trades since the proxy

No insider equity transactions reported since the proxy statement.

Sources (18 citations)

Each figure is listed with the filing it comes from, where it appears in that filing, and the value as printed. Any figure can be independently confirmed against the source.

  • Section 01, Esther Rajavelu. DEF 14A, filed 2026-04-27. Section “Executive Compensation”. As printed: 2,061,496. View filing ↗
  • Section 01, Satyavrat Shukla. DEF 14A, filed 2026-04-27. Section “Executive Compensation”. As printed: 2,025,178. View filing ↗
  • Section 01, Tim Keutzer. DEF 14A, filed 2026-04-27. Section “Executive Compensation”. As printed: 1,440,820. View filing ↗
  • Section 08, John C. Pottage Jr., M.D. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 332,800. View filing ↗
  • Section 08, Frank E. Thomas. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 187,800. View filing ↗
  • Section 08, Patrick Vink, M.D. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 141,550. View filing ↗
  • Section 08, Milind Deshpande, Ph.D. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 120,300. View filing ↗
  • Section 08, Cynthia Smith. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 117,800. View filing ↗
  • Section 08, Scott Jackson. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 115,300. View filing ↗
  • Section 08, Kathleen Tregoning. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 107,800. View filing ↗
  • Section 08, Ankit Mahadevia, M.D. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 102,800. View filing ↗
  • Section 08, Esther Rajavelu. DEF 14A, filed 2026-04-27. Section “Director Compensation”. As printed: 0. View filing ↗
  • Section 06, 2026 vote. Form 8-K, filed 2026-06-25. Item 5.07 · say-on-pay result. As reported: 96.53% (votes for as printed: 27,890,254). View filing ↗
  • Section 06, 2025 vote. Form 8-K, filed 2025-06-18. Item 5.07 · say-on-pay result. As reported: 97.53% (votes for as printed: 25,178,672). View filing ↗
  • Section 06, 2024 vote. Form 8-K, filed 2024-06-03. Item 5.07 · say-on-pay result. As reported: 98.18% (votes for as printed: 23,890,281). View filing ↗
  • Section 01 trend, Δ column (computed). Computed. Δ = current-FY total − prior-FY total per named officer.
  • Section 09b board cost (computed). Computed. Cash 538,750 + equity 462,400 + all other 225,000 = 1,226,150, summed across the director compensation table rows.
  • Spero Therapeutics, Inc. (subject), Section 10b CEO total. DEF 14A, filed 2026-04-27. CEO total compensation as printed in Spero Therapeutics, Inc.'s own proxy. As printed: 2,061,496. View filing ↗
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