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Companies Karyopharm Therapeutics

Karyopharm Therapeutics (KPTI): executive pay, fiscal 2025

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CEO total pay$2,320,902CEO Richard Paulson · source
Say-on-pay support87.84%Latest vote · source

CEO pay, last three years

  • $2,626,288FY2023
  • $2,069,341FY2024
  • $2,320,902FY2025

CEO total pay was $2,320,902 in fiscal 2025, up from $2,069,341 in fiscal 2024.

FY2025: salary $770,000 · bonus $100,100 · stock awards $838,996 · option awards $241,544

Executives and directors

Frequently asked questions

Who was the highest-paid executive at Karyopharm Therapeutics in fiscal 2025?
As disclosed, Richard Paulson (President and Chief Executive Officer) was the highest-paid executive at Karyopharm Therapeutics in fiscal 2025, with total compensation of $2,320,902.
How did shareholders vote on Karyopharm Therapeutics's executive compensation?
As disclosed, 87.84% of shareholders supported Karyopharm Therapeutics's executive compensation in the latest say-on-pay vote.
How much does Karyopharm Therapeutics spend in total on board compensation for fiscal 2025?
As disclosed, Karyopharm Therapeutics reported total board compensation of $596,413 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

Full detail

Every table from the filing. Open any section.

Summary compensation table
Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Richard Paulson$770,000$100,100$838,996$241,544$350,350$0$19,912$2,320,902
President and Chief Executive Officer
Reshma Rangwala567,7361,051,09679,492120,766178,837018,2072,016,134
Executive Vice President, Chief Medical Officer and Head of Research
Stuart Poulton500,135295,012312,293115,736157,543018,8611,399,580
Executive Vice President, Chief Development Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Richard Paulson$2,320,902$2,069,341$2,626,288↑ +251,561
Reshma Rangwala2,016,1341,124,4441,227,789↑ +891,690
Stuart Poulton1,399,580—1,109,115—

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

Incentive-plan design — the Compensation Discussion & Analysis

Our executive compensation program is designed to attract and retain top talent, reward strong performance, and align incentives with the creation of long-term stockholder value, while also considering the Company’s cash and equity resource constraints.

CEO STI target (% of salary)65%
CEO LTI target (% of salary)—
Independent consultantAlpine, WTW
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingtrue
Equity grants and outstanding awards

No plan-based awards are on file for this fiscal year.

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Stuart PoultonOption181154.95—
Stuart PoultonRSU416—3,062
Stuart PoultonOption43869.15—
Reshma RangwalaOption55691.5—
Stuart PoultonRSU750—5,520
Richard PaulsonOption999154.95—
Reshma RangwalaRSU1,083—7,971
Stuart PoultonPSU1,779—13,093
Reshma RangwalaPSU1,889—13,903
Stuart PoultonRSU2,111—15,537
Reshma RangwalaRSU2,222—16,354
Stuart PoultonPSU2,688—19,784
Reshma RangwalaPSU2,842—20,917
Stuart PoultonRSU4,583—33,731
Reshma RangwalaRSU4,583—33,731
Richard PaulsonRSU4,812—35,416
Stuart PoultonRSU5,000—36,800
Reshma RangwalaRSU5,416—39,862
Richard PaulsonRSU5,600—41,216
Richard PaulsonPSU5,600—41,216
Stuart PoultonRSU8,364—61,559
Reshma RangwalaRSU8,842—65,077
Stuart PoultonOption9,1667.95—
Reshma RangwalaOption9,1667.95—
Stuart PoultonOption10,0007.95—
Reshma RangwalaOption10,8337.95—
Richard PaulsonPSU14,760—108,634
Richard PaulsonRSU19,680—144,845
Richard PaulsonRSU20,000—147,200
Stuart PoultonRSU39,682—292,060
Richard PaulsonOption40,0007.95—
Richard PaulsonRSU114,285—841,138
Director compensation
DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Barry E. GreeneIndependent · Lead Independent Director · Compensation Committee · Nominating, Corporate Governance Compliance Committee (Chair)$115,000$0$15,142—$0$130,142
Mansoor Raza Mirza, M.DIndependent · Commercialization and Portfolio41,413015,142—60,000116,555
Deepika R. Pakianathan, Ph.DIndependent90,000015,142—0105,142
Garen G. BohlinIndependent · Audit Committee (Chair) · Nominating, Corporate Governance Compliance Committee80,000015,142—095,142
Christy J. OligerIndependent · Compensation Committee · Commercialization and Portfolio Committee (Chair)80,000015,142—095,142
Chen Schor, M.B.A., C.P.AIndependent70,000015,142—085,142
Zhen Su, M.D., M.B.AIndependent · Commercialization and Portfolio60,000015,142—075,142
Richard Paulson, M.B.AEmployee director000—00

Board fee structure and ownership guideline

Annual cash retainer$50,000
Annual equity retainer$15,142
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)20,000 / 20,000 / 20,000
Stock ownership guideline—

Total cost of the board

ComponentFY2025
Cash retainers and fees$536,413
Equity awards (grant-date value)$0
All other compensation$60,000
Total cost of the board$596,413

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

Peer group, and who names Karyopharm Therapeutics as a peer

Companies that benchmark against KPTI

17 companies name KPTI as a compensation peer

The list of companies that name KPTI as a peer is temporarily unavailable — recheck shortly.

Disclosed peer group — fiscal year 2025

The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.

Alpine

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company’s own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Karyopharm Therapeutics2025Richard Paulson$770,000$838,996$241,544$350,350$2,320,902

Each peer’s compensation is from its most recently filed proxy; fiscal years differ by company. Each peer’s figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

Say-on-pay history and pay ratio
Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-05-2110,025,1981,388,27417,21387.84%Passed
20252025-05-282,716,9511,041,611296,61172.29%Passed
20242024-05-2955,719,91712,055,04465,93082.21%Passed
20232023-05-2464,822,47517,787,485275,73878.47%Passed
20222022-05-1947,288,4396,790,078230,06587.44%Passed
20212021-05-2137,981,9622,969,679122,93692.75%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year’s compensation.

Say-on-pay — history, company’s computation

Meeting yearMeeting dateApproval — company’s computation
20262026-05-2187.84%a
20252025-05-2872.29%b
20242024-05-2982.21%c

a. Voting standard not stated in the filing.

b. Voting standard not stated in the filing.

c. Voting standard not stated in the filing.

Approval percentages are the company’s own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

CEO pay ratio

Ratio (CEO : median employee)—
CEO total compensation—
Median employee compensation—
Insider trades since the proxy

Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.

InsiderRoleTransaction dateCodeSharesPriceValueSecuritySource
Reshma RangwalaEVP & Chief Medical Officer2026-04-21D449$9$4,014CommonForm 4 ↗
Kristin AbateChief Accounting Officer2026-05-13A12100CommonForm 4 ↗
Michael ManoEVP, CLO&Secretary2026-05-13A70000CommonForm 4 ↗
Richard PaulsonDirector2026-05-13A4,92000CommonForm 4 ↗
Sohanya Roshan ChengEVP & Chief Commercial Officer2026-05-13A94700CommonForm 4 ↗
Reshma RangwalaEVP & Chief Medical Officer2026-05-13A94700CommonForm 4 ↗
Stuart PoultonEVP, Chief Development Officer2026-05-13A89600CommonForm 4 ↗
Michael ManoEVP, CLO&Secretary2026-05-14D266102,527CommonForm 4 ↗
Sohanya Roshan ChengEVP & Chief Commercial Officer2026-05-14D324103,078CommonForm 4 ↗
Reshma RangwalaEVP & Chief Medical Officer2026-05-14D408103,876CommonForm 4 ↗
Stuart PoultonEVP, Chief Development Officer2026-05-14D403103,829CommonForm 4 ↗
Richard PaulsonDirector2026-05-14D2,2031020,929CommonForm 4 ↗
Kristin AbateChief Accounting Officer2026-05-14D5310504CommonForm 4 ↗
Barry E. GreeneDirector2026-05-21A15,50800CommonForm 4 ↗
Garen G. BohlinDirector2026-05-21A15,50800CommonForm 4 ↗
Zhen SuDirector2026-05-21A15,50800CommonForm 4 ↗
Deepika PakianathanDirector2026-05-21A15,50800CommonForm 4 ↗
Chen SchorDirector2026-05-21A15,50800CommonForm 4 ↗
Christy J. OligerDirector2026-05-21A15,50800CommonForm 4 ↗
Stuart PoultonEVP, Chief Development Officer2026-07-28D18971,342CommonForm 4 ↗
Kristin AbateChief Accounting Officer2026-09-01D19238CommonForm 4 ↗
Kristin AbateChief Accounting Officer2026-10-01D3781450CommonForm 4 ↗
Kristin AbateChief Accounting Officer2026-10-16D4,78801,647CommonForm 4 ↗

Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.

Sources (41 citations)

Each figure is listed with the filing it comes from, where it appears in that filing, and the value as printed. Any figure can be independently confirmed against the source.

  • Section 01, Richard Paulson. DEF 14A, filed 2026-04-13. Section “025 Summary Compensation Table” · page 61. As printed: 2,320,902. View filing ↗
  • Section 01, Reshma Rangwala. DEF 14A, filed 2026-04-13. Section “025 Summary Compensation Table” · page 61. As printed: 2,016,134. View filing ↗
  • Section 01, Stuart Poulton. DEF 14A, filed 2026-04-13. Section “025 Summary Compensation Table” · page 61. As printed: 1,399,580. View filing ↗
  • Section 07, pay ratio. 10-K, filed 2026-02-13. Section “CEO Pay Ratio”. As printed: —. View filing ↗
  • Section 08, Barry E. Greene. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 130,142. View filing ↗
  • Section 08, Mansoor Raza Mirza, M.D. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 116,555. View filing ↗
  • Section 08, Deepika R. Pakianathan, Ph.D. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 105,142. View filing ↗
  • Section 08, Garen G. Bohlin. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 95,142. View filing ↗
  • Section 08, Christy J. Oliger. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 95,142. View filing ↗
  • Section 08, Chen Schor, M.B.A., C.P.A. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 85,142. View filing ↗
  • Section 08, Zhen Su, M.D., M.B.A. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 75,142. View filing ↗
  • Section 08, Richard Paulson, M.B.A. DEF 14A, filed 2026-04-13. Section “Director Compensation”. As printed: 0. View filing ↗
  • Section 02, Reshma Rangwala 2026-04-21. Form 4, filed 2026-04-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Kristin Abate 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Michael Mano 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Richard Paulson 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Sohanya Roshan Cheng 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Reshma Rangwala 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Stuart Poulton 2026-05-13. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Michael Mano 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Sohanya Roshan Cheng 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Reshma Rangwala 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Stuart Poulton 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Richard Paulson 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Kristin Abate 2026-05-14. Form 4, filed 2026-05-15. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Barry E. Greene 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Garen G. Bohlin 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Zhen Su 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Deepika Pakianathan 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Chen Schor 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Christy J. Oliger 2026-05-21. Form 4, filed 2026-05-26. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Stuart Poulton 2026-07-28. Form 4, filed 2026-07-30. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Kristin Abate 2026-09-01. Form 4, filed 2026-09-02. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Kristin Abate 2026-10-01. Form 4, filed 2026-10-02. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Kristin Abate 2026-10-16. Form 4, filed 2026-10-19. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 06, 2026 vote. Form 8-K, filed 2026-05-28. Item 5.07 · say-on-pay result. As reported: 87.84% (votes for as printed: 10,025,198). View filing ↗
  • Section 06, 2025 vote. Form 8-K, filed 2025-05-29. Item 5.07 · say-on-pay result. As reported: 72.29% (votes for as printed: 2,716,951). View filing ↗
  • Section 06, 2024 vote. Form 8-K, filed 2024-05-31. Item 5.07 · say-on-pay result. As reported: 82.21% (votes for as printed: 55,719,917). View filing ↗
  • Section 01 trend, Δ column (computed). Computed. Δ = current-FY total − prior-FY total per named officer.
  • Section 09b board cost (computed). Computed. Cash 536,413 + equity 0 + all other 60,000 = 596,413, summed across the director compensation table rows.
  • Karyopharm Therapeutics (subject), Section 10b CEO total. DEF 14A, filed 2026-04-13. CEO total compensation as printed in Karyopharm Therapeutics's own proxy. As printed: 2,320,902. View filing ↗
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