Velarion · Company Intelligence
Compensation Brief
Fiscal year 2024 · Filings through 2025-12-05

Avenue Therapeutics (ATXI)

CEO Alexandra MacLean was paid $840,100 in fiscal year 2024, ↓ down 30.8% from fiscal year 2023 (SEC filing 0001437749-25-037023 ↗): executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$840,100 ↓
Alexandra MacLean total, FY2024
—
CEO pay percentile vs peers
—
CEO-to-median pay ratio
98.67%
Say-on-pay support, latest vote

ATXI's next annual pay disclosure, estimated December 5, 2026.est. Filing ↗

01

Summary Compensation Table — fiscal year 2024

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Alexandra MacLean$420,000$0$406,300$0$0$0$13,800$840,100
Chief Executive Officer
David Jin00155,3500000155,350
Interim Chief Financial Officer and Chief Operating Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2024 totalFY2023 totalFY2022 totalΔ FY2023→2024
Alexandra MacLean$840,100$1,213,200—↓ −373,100
David Jin155,350260,000—↓ −104,650

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

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Companies that benchmark against ATXI
1 company names ATXI as a compensation peer

Each company listed discloses ATXI in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named ATXI in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

04

Outstanding equity awards at fiscal year-end 2024

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Alexandra MacLeanRSU85,000—$170,000
David JinRSU32,500—65,000
Alexandra MacLeanOption5,33285.5—
David JinOption1,66785.5—
05

Incentive-plan design — the Compensation Discussion & Analysis

The Company's compensation program is designed to attract, retain, and motivate highly qualified executives by providing competitive base salaries and discretionary annual bonuses based on corporate factors and individual performance, alongside long-term equity awards to align executive interests with stockholders.

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultant—
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingfalse
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20232023-06-229,541,965128,47232,59798.67%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20232023-06-2298.67%a

a. Voting standard not stated in the filing.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

08

Director compensation — fiscal year 2024

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Jay Kranzler, M.D., PhDIndependent · Board Chair$60,000—$64,530—$50,000$174,530
Neil HerskowitzIndependent · Audit (Chair)60,000—64,530—0124,530
Curtis OltmansIndependent · Audit · Compensation (Chair)50,000—64,530—0114,530
Faith CharlesIndependent · Audit50,000—64,530—0114,530
Lindsay A. Rosenwald, M.DNot independent0—64,530—064,530
Alexandra MacLean, M.DEmployee director—————0
09

Board fee structure and ownership guideline

Annual cash retainer$50,000
Annual equity retainer$30,000
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)10,000
Stock ownership guideline—
09b

Total cost of the board

ComponentFY2024
Cash retainers and fees$220,000
Equity awards (grant-date value)$0
All other compensation$50,000
Total cost of the board$270,000

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Avenue Therapeutics2024Alexandra MacLean$420,000$406,300$0$0$840,100

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10d

Frequently asked questions

Who was the highest-paid executive at Avenue Therapeutics in fiscal 2024?
As disclosed, Alexandra MacLean (Chief Executive Officer) was the highest-paid executive at Avenue Therapeutics in fiscal 2024, with total compensation of $840,100.
How did shareholders vote on Avenue Therapeutics's executive compensation?
As disclosed, 98.67% of shareholders supported Avenue Therapeutics's executive compensation in the latest say-on-pay vote.
How much does Avenue Therapeutics spend in total on board compensation for fiscal 2024?
As disclosed, Avenue Therapeutics reported total board compensation of $270,000 for fiscal 2024.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Alexandra MacLeanDEF 14A2025-12-050001437749-25-037023Section “Summary Compensation Table”. As printed: 840,100. Filing ↗machine: r2 · c28 · span 237985–237992
2Section 01, David JinDEF 14A2025-12-050001437749-25-037023Section “Summary Compensation Table”. As printed: 155,350. Filing ↗machine: r4 · c28 · span 244414–244421
3Section 08, Jay Kranzler, M.D., PhDDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 174,530. Filing ↗machine: span 291857–291864
4Section 08, Neil HerskowitzDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 124,530. Filing ↗machine: span 295951–295958
5Section 08, Curtis OltmansDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 114,530. Filing ↗machine: span 297998–298005
6Section 08, Faith CharlesDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 114,530. Filing ↗machine: span 293903–293910
7Section 08, Lindsay A. Rosenwald, M.DDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 64,530. Filing ↗machine: span 289157–289163
8Section 08, Alexandra MacLean, M.DDEF 14A2025-12-050001437749-25-037023Section “Director Compensation”. As printed: 0. Filing ↗
9Section 06, 2023 voteForm 8-K2023-06-260001104659-23-074745Item 5.07 · say-on-pay result. As reported: 98.67% (votes for as printed: 9,541,965). Filing ↗
10Section 01 trend, Δ column (computed)Computed——Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
11Section 09b board cost (computed)Computed——Cash 220,000 + equity 0 + all other 50,000 = 270,000, summed across the director compensation table rows.machine: formula: Σ = 270,000
12Avenue Therapeutics (subject), Section 10b CEO totalDEF 14A2025-12-050001437749-25-037023CEO total compensation as printed in Avenue Therapeutics's own proxy. As printed: 840,100. Filing ↗machine: r2 · c28 · span 237985–237992

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