Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-09-28

Anavex Life Sciences (AVXL)

Former CEO Christopher Missling was paid $3,959,085 in fiscal year 2025, ↑ up 42.2% from fiscal year 2024 (SEC filing 0001731122-26-001038 ↗): executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$3,959,085 ↑
Christopher Missling total, FY2025
—
CEO pay percentile vs peers
16:1
CEO-to-median pay ratio
83.81%
Say-on-pay support, latest vote

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Sample answer — “What is the CEO’s total compensation?”
- Christopher Missling (Chief Executive Officer), FY2025 total compensation $3,959,085 (base salary $723,485) [exec_comp, SEC accession 0001731122-26-001038, filed 2026-08-11]

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AVXL's next annual pay disclosure, estimated November 27, 2027.est. Filing ↗

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Christopher Missling$723,485$140,000$0$3,083,000$0$0$12,600$3,959,085
Chief Executive Officer
Sandra Boenisch199,85837,7090308,200009,503555,270
Principal Financial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Christopher Missling$3,959,085$2,783,700$3,894,453↑ +1,175,385
Sandra Boenisch555,270402,227501,058↑ +153,043

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

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Companies that benchmark against AVXL
5 companies name AVXL as a compensation peer

Each company listed discloses AVXL in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named AVXL in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

01b

Executives — the named officers

One page per officer: the same table above, read for one person at a time — his own figure and every fiscal year the register holds.

ExecutiveRoleFY2025 total
Christopher MisslingCEO$3,959,085
Sandra BoenischPrincipal Financial Officer$555,270
01c

Board of directors

One page per director: the seat, the committees and the fee table, read for one person at a time.

DirectorRoleFY2025 total
Athanasios SkarpelosFormer director (through FY2025)$348,060
Claus van der VeldenIndependent Director$364,060
Jiong MaChair of the Board$364,060
Peter DonhauserIndependent Director$348,060
Steffen ThomasIndependent Director$348,060
02

Equity transactions since the proxy statement was filed

Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.

InsiderRoleTransaction dateCodeSharesPriceValueSecuritySource
Sandra BoenischPFO & Treasurer2026-09-24A25,000$0$0Derivative, Class A CommonForm 4 ↗
Sandra BoenischPFO & Treasurer2026-09-24A25,00000Derivative, Class A CommonForm 4 ↗
Sandra BoenischPFO & Treasurer2026-09-24A25,00000Derivative, Class A CommonForm 4 ↗
Sandra BoenischPFO & Treasurer2026-09-24A20,00000Derivative, Class A CommonForm 4 ↗

Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.

03

Grants of plan-based awards — fiscal year 2025

ExecutiveAwardGrant dateThresholdTargetGrantedMaximumGrant-date fair value
Christopher MisslingOPTION2025-03-31——500,000—$3,083,000
Sandra BoenischOPTION2025-03-31——50,000—308,200
03b

Vehicle mix — grant-date fair value by award type

Named executive officerTime-vested (RSU)Performance-vested (PSU)Options / SARs% performance-vested
Christopher Missling$0$0$3,083,0000.0%
Sandra Boenisch00308,2000.0%

% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Christopher MisslingOption375,0005.36—
Sandra BoenischOption37,5008.58—
Christopher MisslingOption500,00018.11—
Sandra BoenischOption20,00010.09—
Christopher MisslingOption333,3337.54—
Christopher MisslingOption250,00010.09—
Christopher MisslingOption250,0008.57—
Christopher MisslingOption375,0008.58—
Sandra BoenischOption40,00018.11—
Sandra BoenischOption25,0008.57—
Sandra BoenischOption37,5005.36—
05

Incentive-plan design — the Compensation Discussion & Analysis

The Company's compensation program is designed to attract and retain talent, reward excellent performance, and create incentives for stockholder value creation. The Compensation Committee believes a significant portion of compensation should be tied to variable compensation and long-term value creation to balance financial security with performance-based rewards.

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultant—
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingtrue
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20242024-06-1828,406,1114,728,255759,62583.81%Passed
20212021-05-2529,900,3193,212,520826,66788.1%Passed
20182018-04-179,907,1302,958,367237,97477.01%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20242024-06-1883.81%a
20212021-05-2588.1%b
20182018-04-1777.01%c

a. Approved under the standard stated in the filing — “Abstentions and broker non-votes, if any, will not be treated as votes cast and will have no impact on the proposal.”.

b. Approved under the standard stated in the filing — “Abstentions will be counted as votes present and entitled to vote on the proposals considered at the Annual Meeting and, therefore, will have the effect of votes against Proposals 2, 3, 4 and 5.”.

c. Voting standard not stated in the filing.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

07

CEO pay ratio

Ratio (CEO : median employee)16 : 1
CEO total compensation$3,959,085
Median employee compensation$248,195
08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Claus van der VeldenIndependent · Audit (Chair) · Nominating and Corporate Governance (Chair) · Compensation (Chair) · Executive$41,000$0$323,060$0$0$364,060
Jiong MaIndependent · Board Chair · Audit · Executive41,0000323,06000364,060
Athanasios SkarpelosIndependent · Departed during FY25,0000323,06000348,060
Peter DonhauserIndependent · Nominating and Corporate Governance · Compensation25,0000323,06000348,060
Steffen ThomasIndependent · Audit · Nominating and Corporate Governance · Compensation25,0000323,06000348,060
Axel PaegerIndependent · Executive · Partial-year service · Newly elected——————
Gautam PatelIndependent · Partial-year service——————
Adrian SenderowiczIndependent · Partial-year service · Newly elected——————
09

Board fee structure and ownership guideline

Annual cash retainer$25,000
Annual equity retainer$50,000
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)16,000 / 16,000 / 16,000
Stock ownership guideline—
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$157,000
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$157,000

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Anavex Life Sciences2025Christopher Missling$723,485$0$3,083,000$0$3,959,085

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10d

Frequently asked questions

Who was the highest-paid executive at Anavex Life Sciences in fiscal 2025?
As disclosed, Christopher Missling (Chief Executive Officer) was the highest-paid executive at Anavex Life Sciences in fiscal 2025, with total compensation of $3,959,085.
What is Anavex Life Sciences's CEO-to-median employee pay ratio?
As disclosed, Anavex Life Sciences's CEO-to-median employee pay ratio was 16:1.
How did shareholders vote on Anavex Life Sciences's executive compensation?
As disclosed, 83.81% of shareholders supported Anavex Life Sciences's executive compensation in the latest say-on-pay vote.
How much does Anavex Life Sciences spend in total on board compensation for fiscal 2025?
As disclosed, Anavex Life Sciences reported total board compensation of $157,000 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Christopher MisslingDEF 14A2026-08-110001731122-26-001038Section “Executive Compensation”. As printed: 3,959,085. Filing ↗machine: r1 · c23 · span 248698–248707
2Section 01, Sandra BoenischDEF 14A2026-08-110001731122-26-001038Section “Executive Compensation”. As printed: 555,270. Filing ↗machine: r4 · c23 · span 252476–252483
3Section 03, Christopher Missling OPTIONDEF 14A2026-08-110001731122-26-001038Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: span 248313–248322
4Section 03, Sandra Boenisch OPTIONDEF 14A2026-08-110001731122-26-001038Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗
5Section 07, pay ratioDEF 14A2026-08-110001731122-26-001038Section “CEO Pay Ratio”. As printed: 16 : 1. Filing ↗
6Section 08, Claus van der VeldenDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: 364,060. Filing ↗machine: span 359501–359508
7Section 08, Jiong MaDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: 364,060. Filing ↗machine: span 358336–358343
8Section 08, Athanasios SkarpelosDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: 348,060. Filing ↗machine: span 360768–360775
9Section 08, Peter DonhauserDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: 348,060. Filing ↗machine: span 363076–363083
10Section 08, Steffen ThomasDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: 348,060. Filing ↗machine: span 361916–361923
11Section 08, Axel PaegerDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: —. Filing ↗
12Section 08, Gautam PatelDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: —. Filing ↗
13Section 08, Adrian SenderowiczDEF 14A2026-08-110001731122-26-001038Section “Director Compensation”. As printed: —. Filing ↗
14Section 02, Sandra Boenisch 2026-09-24Form 42026-09-280001731122-26-001296Insider equity transaction reported since the proxy statement. Filing ↗
15Section 02, Sandra Boenisch 2026-09-24Form 42026-09-280001731122-26-001296Insider equity transaction reported since the proxy statement. Filing ↗
16Section 02, Sandra Boenisch 2026-09-24Form 42026-09-280001731122-26-001296Insider equity transaction reported since the proxy statement. Filing ↗
17Section 02, Sandra Boenisch 2026-09-24Form 42026-09-280001731122-26-001296Insider equity transaction reported since the proxy statement. Filing ↗
18Section 06, 2024 voteForm 8-K2024-06-210001731122-24-001003Item 5.07 · say-on-pay result. As reported: 83.81% (votes for as printed: 28,406,111). Filing ↗
19Section 06, 2021 voteForm 8-K2021-05-280001731122-21-000974Item 5.07 · say-on-pay result. As reported: 88.1%. Filing ↗
20Section 06, 2018 voteForm 8-K2018-04-200001615774-18-002786Item 5.07 · say-on-pay result. As reported: 77.01%. Filing ↗
21Section 01 trend, Δ column (computed)Computed——Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
22Section 03b vehicle mix (computed)Computed——RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio
23Section 09b board cost (computed)Computed——Cash 157,000 + equity 0 + all other 0 = 157,000, summed across the director compensation table rows.machine: formula: Σ = 157,000
24Anavex Life Sciences (subject), Section 10b CEO totalDEF 14A2026-08-110001731122-26-001038CEO total compensation as printed in Anavex Life Sciences's own proxy. As printed: 3,959,085. Filing ↗machine: r1 · c23 · span 248698–248707

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