President and Chief Executive Officer · OnKure Therapeutics, Inc. (OKUR)

Nicholas Saccomano

A named executive officer of OnKure Therapeutics in every fiscal year CompBrief holds from FY2024 to FY2025. Every figure below is printed as the company filed it and cited to the filing it came from.

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Total disclosed compensation, FY2025

$1,467,934

FY2024: $9,515,165

1st of 3 named executive officers at OnKure Therapeutics by FY2025 total.

3 named officers on file for OnKure Therapeutics, FY2025

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What this number hides

The filing gives the total. OnKure Therapeutics’s full Executive Compensation Report gives every award, the disclosed peer set and what the total leaves out — the pair adds the board’s.

Compensation figures as of the proxy filed April 21, 2026 (DEF 14A).

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Nicholas Saccomano compensation by year

OnKure Therapeutics Summary Compensation Table · all 2 fiscal years held
In US dollars, as OnKure Therapeutics reports it. Most recent year shaded. Totals are the company’s disclosed totals.
ComponentFY2024FY2025
Salary$462,145$600,000
Bonus$279,598$0
Stock awards$0$0
Option awards$8,773,422$609,934
Non-equity incentive$0$247,500
Pension and deferred compensation$0$0
All other$0$10,500
Total$9,515,165$1,467,934

Each year as stated in that year's proxy. A dash means the company reported no figure in that column. Source: OnKure Therapeutics, Inc. DEF 14A filed April 21, 2026, accession 0001140361-26-015903, and prior-year filings. Open the filing on EDGAR.

How this page was built: the OnKure Therapeutics, Inc. filed document, accession 0001140361-26-015903. Every figure is read from that document and cited to the page and table it appears in. Filed April 21, 2026.

$9.5M
$1.5M
FY24
FY25
SalaryBonusNon-equity incentiveOption awardsAll other

Equity holdings

unvested awards at FY2025 year-end
TypeUnvested unitsValue at year-endExercise price
RSU1,424$4,130—
Option495—$13.99
Option331,364—$18.20
Option100,209—$5.19

Per the Outstanding Equity Awards at Fiscal Year-End table in OnKure Therapeutics, Inc.'s FY2025 proxy; value at the fiscal year-end close, as the company printed it.

OnKure Therapeutics’s named executive officers, FY2025

as the company reported each
Named executive officerRoleFY2025 total
Nicholas Saccomano · this pagePresident and Chief Executive Officer$1,467,934
Jason LeveroneChief Financial Officer$896,167
Samuel AgrestaChief Medical Officer$851,731

Board service

OnKure Therapeutics board · FY2024–FY2025

How this board is paid

Company policy: OnKure Therapeutics pays directors a $40,000 cash retainer. As stated in OnKure Therapeutics's FY2025 proxy.

The full OnKure Therapeutics compensation record

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This page is one person within OnKure Therapeutics's record. The company brief lists every named executive, each linking to their own page.

Compensation, the day it’s disclosed

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How this record is built

Every figure on this page is one figure from a public SEC filing, printed as the filing states it and cited to the document. Compensation totals are OnKure Therapeutics's own disclosed totals, not summed by Velarion. Insider transactions are read from Form 4 filings and cover every line filed since the most recent proxy. Nothing is estimated by Velarion; where the company does not disclose a value the cell reads "—", and a section appears only where the company discloses the data. Corrections: records@velarion.ai.

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Nicholas Saccomano's compensation dossier