Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-04-21

OnKure Therapeutics, Inc. (OKUR)

Fiscal year 2025 executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$1,467,934
Nicholas Saccomano total, FY2025
CEO pay percentile vs peers
CEO-to-median pay ratio
Say-on-pay support, latest vote
Companies that benchmark against OKUR
No companies currently name OKUR as a compensation peer in their most recent disclosure.

This is the complete answer, not a partial one — the list is never padded.

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Nicholas Saccomano$600,000$0$0$609,934$247,500$0$10,500$1,467,934
President and Chief Executive Officer
Jason Leverone444,00000304,967133,200014,000896,167
Chief Financial Officer
Samuel Agresta482,00000211,131144,600014,000851,731
Chief Medical Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY20242025
Nicholas Saccomano$1,467,934$9,515,165−8,047,231
Jason Leverone896,1672,678,570−1,782,403
Samuel Agresta851,7312,841,068−1,989,337

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

03

Grants of plan-based awards — fiscal year 2025

ExecutiveAwardGrant dateThresholdTargetGrantedMaximumGrant-date fair value
Samuel Agresta, M.D.OPTION45,000$211,131
Jason Leverone, C.P.A.OPTION65,000304,967
03b

Vehicle mix — grant-date fair value by award type

Named executive officerTime-vested (RSU)Performance-vested (PSU)Options / SARs% performance-vested
Samuel Agresta, M.D.$0$0$211,1310.0%
Jason Leverone, C.P.A.00304,9670.0%

% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Jason LeveroneRSU5,105$14,805
SaccomanoRSU1,4244,130
SaccomanoOption49513.99
SaccomanoOption331,36418.2
SaccomanoOption100,2095.19
Jason LeveroneOption12121.2
Jason LeveroneOption1,77413.99
Jason LeveroneOption79,81818.2
Jason LeveroneOption50,1055.19
Samuel AgrestaOption10,06913.99
Samuel AgrestaOption80,29818.2
Samuel AgrestaOption34,6885.19
08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Andrew PhillipsIndependent$87,500$0$16,294$103,794
Andrew Phillips, Ph.DIndependent · Audit · Compensation (Chair) · Nominating and Corporate Governance (Chair)87,500016,294103,794
Isaac Manke, Ph.DIndependent60,497016,29476,791
Isaac MankeIndependent60,497016,29476,791
R. Michael CarruthersIndependent · Audit (Chair)55,000016,29471,294
Edward MathersIndependent · Audit · Compensation44,998016,29461,292
Valerie M. Jansen, M.D., Ph.DIndependent · Nominating and Corporate Governance44,000016,29460,294
Michael GreyIndependent40,000016,29456,294
Dr. SaccomanoEmployee director0
Liam RatcliffeIndependent0000
Liam Ratcliffe, Ph.DIndependent · Departed during FY0000
09

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer
Per board meeting fee
Committee chair fees (audit / comp / nom-gov)15,000 / 5,000 / 4,000
Stock ownership guideline
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$479,992
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$479,992

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1OnKure Therapeutics, Inc.2025Nicholas Saccomano$600,000$0$609,934$247,500$1,467,934

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Nicholas SaccomanoDEF 14A2026-04-210001140361-26-015903Section “Executive Compensation”. As printed: 1,467,934. Filing ↗machine: r2 · c18 · span 534923–534932
2Section 01, Jason LeveroneDEF 14A2026-04-210001140361-26-015903Section “Executive Compensation”. As printed: 896,167. Filing ↗machine: r6 · c18 · span 548645–548652
3Section 01, Samuel AgrestaDEF 14A2026-04-210001140361-26-015903Section “Executive Compensation”. As printed: 851,731. Filing ↗machine: r4 · c18 · span 541794–541801
4Section 03, Samuel Agresta, M.D. OPTIONDEF 14A2026-04-210001140361-26-015903Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 483349–483356
5Section 03, Jason Leverone, C.P.A. OPTIONDEF 14A2026-04-210001140361-26-015903Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 480440–480447
6Section 08, Andrew PhillipsDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 103,794. Filing ↗machine: span 284670–284849
7Section 08, Andrew Phillips, Ph.DDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 103,794. Filing ↗machine: span 284670–284849
8Section 08, Isaac Manke, Ph.DDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 76,791. Filing ↗machine: span 279858–280076
9Section 08, Isaac MankeDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 76,791. Filing ↗machine: span 279858–280076
10Section 08, R. Michael CarruthersDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 71,294. Filing ↗machine: span 282088–282306
11Section 08, Edward MathersDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 61,292. Filing ↗machine: span 291665–291883
12Section 08, Valerie M. Jansen, M.D., Ph.DDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 60,294. Filing ↗machine: span 286870–287088
13Section 08, Michael GreyDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 56,294. Filing ↗machine: span 289442–289660
14Section 08, Dr. SaccomanoDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 0. Filing ↗
15Section 08, Liam RatcliffeDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 0. Filing ↗
16Section 08, Liam Ratcliffe, Ph.DDEF 14A2026-04-210001140361-26-015903Section “Director Compensation”. As printed: 0. Filing ↗
17Section 01 trend, Δ column (computed)ComputedcomputedΔ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
18Section 03b vehicle mix (computed)ComputedcomputedRSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio
19Section 09b board cost (computed)ComputedcomputedCash 479,992 + equity 0 + all other 0 = 479,992, summed across the director compensation table rows.machine: formula: Σ = 479,992
20OnKure Therapeutics, Inc. (subject), Section 10b CEO totalDEF 14A2026-04-210001140361-26-015903CEO total compensation as printed in OnKure Therapeutics, Inc.'s own proxy. As printed: 1,467,934. Filing ↗machine: r2 · c18 · span 534923–534932