Chief Medical Officer · OnKure Therapeutics, Inc. (OKUR)

Samuel Agresta

A named executive officer of OnKure Therapeutics in every fiscal year CompBrief holds from FY2024 to FY2025. Every figure below is printed as the company filed it and cited to the filing it came from.

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Total disclosed compensation, FY2025

$851,731

FY2024: $2,841,068

3rd of 3 named executive officers at OnKure Therapeutics by FY2025 total.

3 named officers on file for OnKure Therapeutics, FY2025

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What this number hides

The filing gives the total. OnKure Therapeutics’s full Executive Compensation Report gives every award, the disclosed peer set and what the total leaves out — the pair adds the board’s.

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Compensation figures as of the proxy filed April 21, 2026 (DEF 14A).

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Samuel Agresta compensation by year

OnKure Therapeutics Summary Compensation Table · all 2 fiscal years held
In US dollars, as OnKure Therapeutics reports it. Most recent year shaded. Totals are the company’s disclosed totals.
ComponentFY2024FY2025
Salary$416,727$482,000
Bonus$183,360$0
Stock awards$0$0
Option awards$2,228,619$211,131
Non-equity incentive$0$144,600
Pension and deferred compensation$0$0
All other$12,362$14,000
Total$2,841,068$851,731

Each year as stated in that year's proxy. A dash means the company reported no figure in that column. Source: OnKure Therapeutics, Inc. DEF 14A filed April 21, 2026, accession 0001140361-26-015903, and prior-year filings. Open the filing on EDGAR.

How this page was built: the OnKure Therapeutics, Inc. filed document, accession 0001140361-26-015903. Every figure is read from that document and cited to the page and table it appears in. Filed April 21, 2026.

$2.8M
$852K
FY24
FY25
SalaryBonusNon-equity incentiveOption awardsAll other

Equity holdings

unvested awards at FY2025 year-end
TypeUnvested unitsValue at year-endExercise price
Option80,298—$18.20
Option34,688—$5.19
Option10,069—$13.99

Per the Outstanding Equity Awards at Fiscal Year-End table in OnKure Therapeutics, Inc.'s FY2025 proxy; value at the fiscal year-end close, as the company printed it.

OnKure Therapeutics’s named executive officers, FY2025

as the company reported each
Named executive officerRoleFY2025 total
Nicholas SaccomanoPresident and Chief Executive Officer$1,467,934
Jason LeveroneChief Financial Officer$896,167
Samuel Agresta · this pageChief Medical Officer$851,731

Samuel Agresta's compensation dossier, OnKure Therapeutics

You have read Samuel Agresta's totals and holdings. The dossier adds each equity grant OnKure Therapeutics disclosed for Samuel Agresta and OnKure Therapeutics's own disclosed peer group, where the company discloses them, with every row in a PDF and a CSV cited to its filing.

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The full OnKure Therapeutics compensation record

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This page is one person within OnKure Therapeutics's record. The company brief lists every named executive, each linking to their own page.

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How this record is built

Every figure on this page is one figure from a public SEC filing, printed as the filing states it and cited to the document. Compensation totals are OnKure Therapeutics's own disclosed totals, not summed by Velarion. Insider transactions are read from Form 4 filings and cover every line filed since the most recent proxy. Nothing is estimated by Velarion; where the company does not disclose a value the cell reads "—", and a section appears only where the company discloses the data. Corrections: records@velarion.ai.

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Samuel Agresta's compensation dossier