Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-03-26

Alto Neuroscience (ANRO)

CEO Amit Etkin was paid $2,188,487 in fiscal year 2025 (SEC filing 0001104659-26-035180 ↗): executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$2,188,487
Amit Etkin total, FY2025
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CEO pay percentile vs peers
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CEO-to-median pay ratio
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Sample answer — “What is the CEO’s total compensation?”
- Amit Etkin (President, Chief Executive Officer, and Chair of the Board), FY2025 total compensation $2,188,487 (base salary $650,671) [exec_comp, SEC accession 0001104659-26-035180, filed 2026-03-26]

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ANRO's next annual pay disclosure, estimated March 26, 2027.est. Filing ↗

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Amit Etkin$650,671$220,000$0$934,186$358,072$0$25,558$2,188,487
President, Chief Executive Officer, and Chair of the Board
Nicholas Smith493,720220,0000594,723222,300010,8421,541,585
Chief Financial Officer and Chief Business Officer
Michael Hanley488,80000517,598195,520011,0101,212,928
Chief Operating Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Amit Etkin$2,188,487$4,065,848—↓ −1,877,361
Nicholas Smith1,541,5851,995,964—↓ −454,379
Michael Hanley1,212,9282,442,628—↓ −1,229,700

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

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Companies that benchmark against ANRO
1 company names ANRO as a compensation peer

Each company listed discloses ANRO in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named ANRO in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

01c

Board of directors

One page per director: the seat, the committees and the fee table, read for one person at a time.

DirectorRoleFY2025 total
Andrew DreyfusIndependent Director$80,263
Christopher Nixon CoxLead Independent Director$110,543
Gwill YorkIndependent Director$88,178
Husseini Manji, M.DIndependent Director$73,129
Maha Radhakrishnan, M.DFormer director (through FY2025)$17,906
Po Yu (Jeff) Chen, Ph.DFormer director (through FY2025)$19,747
Raymond Sanchez, M.DIndependent Director$84,904
02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Nicholas SmithOption135,0004.2—
Nicholas SmithRSU24,670—9,163
Amit EtkinRSU215,000—107,502
Amit EtkinRSU97,563—48,782
Nicholas SmithRSU39,375—19,688
Amit EtkinRSU164,859—82,431
Michael HanleyOption125,0004.2—
Michael HanleyRSU74,417—113,583
Nicholas SmithRSU134,886—67,443
Nicholas SmithRSU36,531—8,431
Michael HanleyRSU8,000—12,210
Amit EtkinRSU25,243—9,377
05

Incentive-plan design — the Compensation Discussion & Analysis

The company's compensation philosophy is designed to align the interests of named executive officers with those of stockholders by providing a fixed base salary reflecting skill and market levels, annual incentive compensation based on individual and corporate performance, and equity-based awards that serve as retention measures and incentivize the achievement of corporate goals.

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultantAon Consulting, Inc.
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingtrue
07

CEO pay ratio

Ratio (CEO : median employee)—
CEO total compensation—
Median employee compensation—
08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Christopher Nixon CoxIndependent · Lead Independent Director · Audit · Compensation (Chair) · Nominating and Corporate Governance$4,390—$106,153——$110,543
Gwill YorkIndependent · Audit (Chair) · Compensation0—88,178——88,178
Raymond Sanchez, M.DIndependent · Nominating and Corporate Governance8,682—76,222——84,904
Andrew DreyfusIndependent · Audit · Compensation54,000—26,263——80,263
Husseini Manji, M.DIndependent · Nominating and Corporate Governance (Chair)1,929—71,200——73,129
Po Yu (Jeff) Chen, Ph.DIndependent · Departed during FY19,747—0——19,747
Maha Radhakrishnan, M.DIndependent · Departed during FY17,906—0——17,906
Amit Etkin, M.D., Ph.DEmployee director · Board Chair—————0
09

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer—
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)16,000 / 12,000 / 10,000
Stock ownership guideline—
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$106,654
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$106,654

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Alto Neuroscience2025Amit Etkin$650,671$0$934,186$358,072$2,188,487

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10d

Frequently asked questions

Who was the highest-paid executive at Alto Neuroscience in fiscal 2025?
As disclosed, Amit Etkin (President, Chief Executive Officer, and Chair of the Board) was the highest-paid executive at Alto Neuroscience in fiscal 2025, with total compensation of $2,188,487.
How much does Alto Neuroscience spend in total on board compensation for fiscal 2025?
As disclosed, Alto Neuroscience reported total board compensation of $106,654 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Amit EtkinDEF 14A2026-03-260001104659-26-035180Section “Summary Compensation Table”. As printed: 2,188,487. Filing ↗machine: r1 · c47 · span 533298–533307
2Section 01, Nicholas SmithDEF 14A2026-03-260001104659-26-035180Section “Summary Compensation Table”. As printed: 1,541,585. Filing ↗machine: r3 · c47 · span 542740–542749
3Section 01, Michael HanleyDEF 14A2026-03-260001104659-26-035180Section “Summary Compensation Table”. As printed: 1,212,928. Filing ↗machine: r5 · c47 · span 552122–552131
4Section 07, pay ratio10-K2026-03-160001999480-26-000002Section “CEO Pay Ratio”. As printed: —. Filing ↗
5Section 08, Christopher Nixon CoxDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 110,543. Filing ↗machine: span 276020–276027
6Section 08, Gwill YorkDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 88,178. Filing ↗machine: span 286113–286119
7Section 08, Raymond Sanchez, M.DDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 84,904. Filing ↗machine: span 284511–284517
8Section 08, Andrew DreyfusDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 80,263. Filing ↗machine: span 278127–278133
9Section 08, Husseini Manji, M.DDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 73,129. Filing ↗machine: span 280213–280219
10Section 08, Po Yu (Jeff) Chen, Ph.DDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 19,747. Filing ↗machine: span 272920–272926
11Section 08, Maha Radhakrishnan, M.DDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 17,906. Filing ↗machine: span 281416–281422
12Section 08, Amit Etkin, M.D., Ph.DDEF 14A2026-03-260001104659-26-035180Section “Director Compensation”. As printed: 0. Filing ↗
13Section 01 trend, Δ column (computed)Computed——Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
14Section 09b board cost (computed)Computed——Cash 106,654 + equity 0 + all other 0 = 106,654, summed across the director compensation table rows.machine: formula: Σ = 106,654
15Alto Neuroscience (subject), Section 10b CEO totalDEF 14A2026-03-260001104659-26-035180CEO total compensation as printed in Alto Neuroscience's own proxy. As printed: 2,188,487. Filing ↗machine: r1 · c47 · span 533298–533307

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