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Companies CytomX Therapeutics, Inc.

CytomX Therapeutics (CTMX): executive pay, fiscal 2025

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CEO total pay$4,738,495CEO Sean McCarthy · source
Say-on-pay support98.84%Latest vote · source
CEO vs. named peers57th pct.Against its disclosed peer group
CEO pay ratio30:1To the median employee · source

CEO pay, last three years

  • $2,611,138FY2023
  • $1,752,802FY2024
  • $4,738,495FY2025

CEO total pay was $4,738,495 in fiscal 2025, up from $1,752,802 in fiscal 2024.

FY2025: salary $675,290 · stock awards $1,150,463 · option awards $2,158,170

Frequently asked questions

Who was the highest-paid executive at CytomX Therapeutics, Inc. in fiscal 2025?
As disclosed, Sean McCarthy (Chief Executive Officer and Chairman of the Board of Directors) was the highest-paid executive at CytomX Therapeutics, Inc. in fiscal 2025, with total compensation of $4,738,495.
How does CytomX Therapeutics, Inc.'s chief executive pay compare to its disclosed peer group?
As disclosed, Sean McCarthy's total compensation ranked at the 57th percentile of CytomX Therapeutics, Inc.'s disclosed peer group.
What is CytomX Therapeutics, Inc.'s CEO-to-median employee pay ratio?
As disclosed, CytomX Therapeutics, Inc.'s CEO-to-median employee pay ratio was 30:1.
How did shareholders vote on CytomX Therapeutics, Inc.'s executive compensation?
As disclosed, 98.84% of shareholders supported CytomX Therapeutics, Inc.'s executive compensation in the latest say-on-pay vote.
How much does CytomX Therapeutics, Inc. spend in total on board compensation for fiscal 2025?
As disclosed, CytomX Therapeutics, Inc. reported total board compensation of $330,500 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

Full detail

Every table from the filing. Open any section.

Summary compensation table
Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Sean McCarthy$675,290—$1,150,463$2,158,170$749,572$0$5,000$4,738,495
Chief Executive Officer and Chairman of the Board of Directors
Rachael Lester77,019120,000—1,993,35544,500002,234,874
Senior Vice President and Chief Business Officer
Chris Ogden478,650—224,928446,369387,68405,0001,542,631
Senior Vice President, and Chief Financial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Sean McCarthy$4,738,495$1,752,802—↑ +2,985,693
Rachael Lester2,234,874———
Chris Ogden1,542,631914,279—↑ +628,352

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

Incentive-plan design — the Compensation Discussion & Analysis

The Compensation Committee's objective is to have compensation programs and practices that are competitive with our peers and industry through a mix of cash (base salary and annual, performance-based cash incentive bonuses) and long-term incentives (equity awards).

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultantAon
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingfalse
Equity grants and outstanding awards

Grants of plan-based awards — fiscal year 2025

ExecutiveAwardGrant dateThresholdTargetGrantedMaximumGrant-date fair value
Sean A. McCarthy D. PhilOPTION2025-02-05——390,000—$336,960
Chris OgdenOPTION2025-02-05——340,000—293,760
Sean A. McCarthy D. PhilOPTION2025-02-05——800,000—691,200
Chris OgdenOPTION2025-02-05——225,000—194,400

Vehicle mix — grant-date fair value by award type

Named executive officerTime-vested (RSU)Performance-vested (PSU)Options / SARs% performance-vested
Sean A. McCarthy D. Phil$0$0$1,028,1600.0%
Chris Ogden00488,1600.0%

% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Chris OgdenOption6084.13—
Chris OgdenRSU1,822—7,762
Chris OgdenRSU8,333—35,499
Chris OgdenRSU11,666—49,697
Sean McCarthyRSU18,750—79,875
Sean McCarthyOption18,7504.13—
Chris OgdenOption21,8752.59—
Chris OgdenRSU26,666—113,597
Sean McCarthyRSU35,000—149,100
Chris OgdenPSU37,500—38,625
Chris OgdenPSU37,500—159,750
Chris OgdenPSU39,150—166,779
Chris OgdenRSU44,000—187,440
Chris OgdenOption46,8751.49—
Chris OgdenRSU57,500—244,950
Sean McCarthyRSU60,000—255,600
Chris OgdenOption67,0840.86—
Chris OgdenOption73,3602.9—
Chris OgdenOption80,2091.68—
Sean McCarthyOption91,8752.59—
Sean McCarthyPSU130,000—553,800
Chris OgdenOption178,1250.86—
Sean McCarthyRSU180,000—766,800
Sean McCarthyRSU195,000—830,700
Sean McCarthyOption218,7501.68—
Sean McCarthyOption227,5000.86—
Sean McCarthyPSU285,000—1,214,100
Sean McCarthyOption534,3752.9—
Sean McCarthyOption633,3340.86—
Rachael LesterOption650,0003.74—
Director compensation
DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Matthew P. YoungIndependent · Audit$80,000—$87,514——$167,514
Halley GilbertIndependent · Audit · Nominating and Corporate Governance55,500—87,514——143,014
James R. MeyersIndependent · Compensation52,000—87,514——139,514
Elaine V. JonesIndependent · Compensation · Nominating and Corporate Governance50,000—87,514——137,514
Mani MohindruIndependent · Audit49,000—87,514——136,514
Alan AshworthIndependent · Nominating and Corporate Governance44,000—87,514——131,514

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer—
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)15,000 / 12,000 / 8,000
Stock ownership guideline—

Total cost of the board

ComponentFY2025
Cash retainers and fees$330,500
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$330,500

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

Peer group, and who names CytomX Therapeutics as a peer

Companies that benchmark against CTMX

7 companies name CTMX as a compensation peer

Each company listed discloses CTMX in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named CTMX in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company’s own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1CytomX Therapeutics, Inc.2025Sean McCarthy$675,290$1,150,463$2,158,170$749,572$4,738,495

Each peer’s compensation is from its most recently filed proxy; fiscal years differ by company. Each peer’s figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

Say-on-pay history and pay ratio
Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-06-17147,127,7151,722,679154,56898.84%Passed
20252025-06-1122,996,8055,349,691193,10981.13%Passed
20242024-05-1527,396,4111,905,83561,70493.5%Passed
20232023-06-1422,139,0701,486,286938,84993.71%Passed
20222022-06-1538,370,1752,802,91184,68793.19%Passed
20212021-06-1644,894,3042,503,266897,93894.72%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year’s compensation.

Say-on-pay — history, company’s computation

Meeting yearMeeting dateApproval — company’s computation
20262026-06-1798.84%a
20252025-06-1181.13%b
20242024-05-1593.5%c

a. Approved under the standard stated in the filing — “• For Proposal 6, being the non-binding advisory vote to approve the compensation of our named executive officers, the proposal must receive a "For" vote from the majority of the votes cast either online or by proxy at the annual meeting and that are entitled to vote on the proposal, with votes cast including votes "Against" and excluding abstentions and broker non-votes.”.

b. Approved under the standard stated in the filing — “• For Proposal 4, being the non-binding advisory vote to approve the compensation of our named executive officers, the proposal must receive a "For" vote from the majority of the votes cast either online or by proxy at the annual meeting and that are entitled to vote on the proposal, with votes cast excluding abstentions and broker non-votes.”.

c. Approved under the standard stated in the filing — “• For Proposal 4, being the non-binding advisory vote to approve the compensation of our named executive officers, the proposal must receive a "For" vote from the majority of the votes cast either online or by proxy at the annual meeting and that are entitled to vote on the proposal, with votes cast excluding abstentions and broker non-votes.”.

Approval percentages are the company’s own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

CEO pay ratio

Ratio (CEO : median employee)30 : 1
CEO total compensation$4,738,495
Median employee compensation—
Insider trades since the proxy

Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.

InsiderRoleTransaction dateCodeSharesPriceValueSecuritySource
Chris OgdenChief Financial Officer2026-06-15D1,624$3$4,953CommonForm 4 ↗
Elaine V. JonesDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Alan AshworthDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Halley GilbertDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
James R. MeyersDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Mani MohindruDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Matthew P. YoungDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Zhen SuDirector2026-06-17A59,00000Derivative, Class A CommonForm 4 ↗
Charles S. FuchsDirector2026-07-24A118,00000Derivative, Class A CommonForm 4 ↗
Alejandra CarvajalChief Legal Officer2026-08-03A450,00000Derivative, Class A CommonForm 4 ↗
Alejandra CarvajalChief Legal Officer2026-08-03A100,00000CommonForm 4 ↗

Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.

Sources (32 citations)

Each figure is listed with the filing it comes from, where it appears in that filing, and the value as printed. Any figure can be independently confirmed against the source.

  • Section 01, Sean McCarthy. DEF 14A, filed 2026-04-30. Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 4,738,495. View filing ↗
  • Section 01, Rachael Lester. DEF 14A, filed 2026-04-30. Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 2,234,874. View filing ↗
  • Section 01, Chris Ogden. DEF 14A, filed 2026-04-30. Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 1,542,631. View filing ↗
  • Section 03, Sean A. McCarthy D. Phil OPTION. DEF 14A, filed 2026-04-30. Section “Executive Compensation” · grants of plan-based awards table. View filing ↗
  • Section 03, Chris Ogden OPTION. DEF 14A, filed 2026-04-30. Section “Executive Compensation” · grants of plan-based awards table. View filing ↗
  • Section 03, Sean A. McCarthy D. Phil OPTION. DEF 14A, filed 2026-04-30. Section “Executive Compensation” · grants of plan-based awards table. View filing ↗
  • Section 03, Chris Ogden OPTION. DEF 14A, filed 2026-04-30. Section “Executive Compensation” · grants of plan-based awards table. View filing ↗
  • Section 07, pay ratio. DEF 14A, filed 2026-04-30. Section “CEO Pay Ratio”. As printed: 30 : 1. View filing ↗
  • Section 08, Matthew P. Young. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 167,514. View filing ↗
  • Section 08, Halley Gilbert. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 143,014. View filing ↗
  • Section 08, James R. Meyers. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 139,514. View filing ↗
  • Section 08, Elaine V. Jones. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 137,514. View filing ↗
  • Section 08, Mani Mohindru. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 136,514. View filing ↗
  • Section 08, Alan Ashworth. DEF 14A, filed 2026-04-30. Section “Director Compensation”. As printed: 131,514. View filing ↗
  • Section 02, Chris Ogden 2026-06-15. Form 4, filed 2026-06-17. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Elaine V. Jones 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Alan Ashworth 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Halley Gilbert 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, James R. Meyers 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Mani Mohindru 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Matthew P. Young 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Zhen Su 2026-06-17. Form 4, filed 2026-06-22. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Charles S. Fuchs 2026-07-24. Form 4, filed 2026-07-30. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Alejandra Carvajal 2026-08-03. Form 4, filed 2026-08-05. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 02, Alejandra Carvajal 2026-08-03. Form 4, filed 2026-08-05. Insider equity transaction reported since the proxy statement. View filing ↗
  • Section 06, 2026 vote. Form 8-K, filed 2026-06-22. Item 5.07 · say-on-pay result. As reported: 98.84% (votes for as printed: 147,127,715). View filing ↗
  • Section 06, 2025 vote. Form 8-K, filed 2025-06-13. Item 5.07 · say-on-pay result. As reported: 81.13% (votes for as printed: 22,996,805). View filing ↗
  • Section 06, 2024 vote. Form 8-K, filed 2024-05-17. Item 5.07 · say-on-pay result. As reported: 93.5% (votes for as printed: 27,396,411). View filing ↗
  • Section 01 trend, Δ column (computed). Computed. Δ = current-FY total − prior-FY total per named officer.
  • Section 03b vehicle mix (computed). Computed. RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).
  • Section 09b board cost (computed). Computed. Cash 330,500 + equity 0 + all other 0 = 330,500, summed across the director compensation table rows.
  • CytomX Therapeutics, Inc. (subject), Section 10b CEO total. DEF 14A, filed 2026-04-30. CEO total compensation as printed in CytomX Therapeutics, Inc.'s own proxy. As printed: 4,738,495. View filing ↗
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