Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-06-22

CytomX Therapeutics (CTMX)

CEO Sean McCarthy was paid $4,738,495 in fiscal year 2025: executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$4,738,495
Sean McCarthy total, FY2025
—
CEO pay percentile vs peers
30:1
CEO-to-median pay ratio
98.84%
Say-on-pay support, latest vote

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Companies that benchmark against CTMX
6 companies name CTMX as a compensation peer

Each company listed discloses CTMX in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named CTMX in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Sean McCarthy$675,290$0$1,150,463$2,158,170$749,572$0$5,000$4,738,495
Chief Executive Officer and Chairman of the Board of Directors
Rachael Lester77,019120,00001,993,35544,500002,234,874
Senior Vice President and Chief Business Officer
Chris Ogden478,6500224,928446,369387,68405,0001,542,631
Senior Vice President, and Chief Financial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Sean McCarthy$4,738,495$1,752,802—+2,985,693
Rachael Lester2,234,874———
Chris Ogden1,542,631914,279—+628,352

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Chris OgdenRSU8,333—$35,499
Chris OgdenOption67,0840.86—
Chris OgdenOption178,1250.86—
Chris OgdenRSU57,500—244,950
Chris OgdenRSU44,000—187,440
Chris OgdenPSU39,150—166,779
Chris OgdenPSU37,500—159,750
Chris OgdenRSU26,666—113,597
Chris OgdenRSU11,666—49,697
Chris OgdenRSU1,822—7,762
Chris OgdenOption6084.13—
Chris OgdenOption21,8752.59—
Chris OgdenOption80,2091.68—
Chris OgdenOption46,8751.49—
Chris OgdenOption73,3602.9—
Rachael LesterOption650,0003.74—
05

Incentive-plan design — the Compensation Discussion & Analysis

The Compensation Committee's objective is to have compensation programs and practices that are competitive with peers and the industry through a mix of cash (base salary and annual, performance-based cash incentive bonuses) and long-term incentives (equity awards). The company aims to create a 'pay for performance' culture by rewarding executives based on actual business results and holding them accountable.

CEO STI target (% of salary)—
CEO LTI target (% of salary)—
Independent consultantAon
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingtrue
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-06-17147,127,7151,722,679154,56898.84%Passed
20252025-06-1122,996,8055,349,691193,10981.13%Passed
20242024-05-1527,396,4111,905,83561,70493.5%Passed
20232023-06-1422,139,0701,486,286938,84993.71%Passed
20222022-06-1538,370,1752,802,91184,68793.19%Passed
20212021-06-1644,894,3042,503,266897,93894.72%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20262026-06-1798.84%a
20252025-06-1181.13%b
20242024-05-1593.5%c

a. Voting standard not stated in the filing.

b. Voting standard not stated in the filing.

c. Voting standard not stated in the filing.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

07

CEO pay ratio

Ratio (CEO : median employee)30 : 1
CEO total compensation—
Median employee compensation—
08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Matthew P. YoungIndependent · Audit$80,000—$87,514——$167,514
Halley GilbertIndependent · Audit · Nominating and Corporate Governance55,500—87,514——143,014
James R. MeyersIndependent · Compensation52,000—87,514——139,514
Elaine V. JonesIndependent · Compensation · Nominating and Corporate Governance50,000—87,514——137,514
Mani MohindruIndependent · Audit49,000—87,514——136,514
Alan AshworthIndependent · Nominating and Corporate Governance44,000—87,514——131,514
09

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer—
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)15,000 / 12,000 / 8,000
Stock ownership guideline—
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$330,500
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$330,500

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1CytomX Therapeutics2025Sean McCarthy$675,290$1,150,463$2,158,170$749,572$4,738,495

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

FAQ

Frequently asked questions

Who was the highest-paid executive at CytomX Therapeutics in fiscal 2025?
Sean McCarthy, Chief Executive Officer and Chairman of the Board of Directors, was the highest-paid executive at CytomX Therapeutics in fiscal 2025 with total compensation of $4,738,495.
How does CytomX Therapeutics's chief executive pay compare to its disclosed peer group?
The filing shows that the CEO pay percentile of disclosed peers is not disclosed in this filing.
What is CytomX Therapeutics's CEO-to-median employee pay ratio?
As disclosed, the CEO-to-median employee pay ratio was 30:1.
How did shareholders vote on CytomX Therapeutics's executive compensation?
The filing shows that 98.84% of shareholders supported the executive compensation vote.
How much does CytomX Therapeutics spend in total on board compensation for fiscal 2025?
The company reported total board compensation of $330,500 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Sean McCarthyDEF 14A2026-04-300001140361-26-018237Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 4,738,495. Filing ↗machine: r2 · c24 · span 739353–739362
2Section 01, Rachael LesterDEF 14A2026-04-300001140361-26-018237Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 2,234,874. Filing ↗machine: r8 · c24 · span 765209–765218
3Section 01, Chris OgdenDEF 14A2026-04-300001140361-26-018237Section “EXECUTIVE COMPENSATION TABLES” · page 53. As printed: 1,542,631. Filing ↗machine: r5 · c24 · span 752434–752443
4Section 07, pay ratioDEF 14A2026-04-300001140361-26-018237Section “CEO Pay Ratio”. As printed: 30 : 1. Filing ↗
5Section 08, Matthew P. YoungDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 167,514. Filing ↗machine: span 637050–637229
6Section 08, Halley GilbertDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 143,014. Filing ↗machine: span 642771–642950
7Section 08, James R. MeyersDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 139,514. Filing ↗machine: span 639045–639224
8Section 08, Elaine V. JonesDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 137,514. Filing ↗machine: span 640777–640956
9Section 08, Mani MohindruDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 136,514. Filing ↗machine: span 635324–635503
10Section 08, Alan AshworthDEF 14A2026-04-300001140361-26-018237Section “Director Compensation”. As printed: 131,514. Filing ↗machine: span 644501–644680
11Section 06, 2026 voteForm 8-K2026-06-220001193125-26-277631Item 5.07 · say-on-pay result. As reported: 98.84% (votes for as printed: 147,127,715). Filing ↗
12Section 06, 2025 voteForm 8-K2025-06-130001193125-25-140739Item 5.07 · say-on-pay result. As reported: 81.13% (votes for as printed: 22,996,805). Filing ↗
13Section 06, 2024 voteForm 8-K2024-05-170001193125-24-141699Item 5.07 · say-on-pay result. As reported: 93.5% (votes for as printed: 27,396,411). Filing ↗
14Section 01 trend, Δ column (computed)Computed——Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
15Section 09b board cost (computed)Computed——Cash 330,500 + equity 0 + all other 0 = 330,500, summed across the director compensation table rows.machine: formula: Σ = 330,500
16CytomX Therapeutics (subject), Section 10b CEO totalDEF 14A2026-04-300001140361-26-018237CEO total compensation as printed in CytomX Therapeutics's own proxy. As printed: 4,738,495. Filing ↗machine: r2 · c24 · span 739353–739362

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