Velarion · Company Intelligence
Compensation Brief
Fiscal year 2023 · Filings through 2026-03-26

Regulus Therapeutics (RGLS)

Fiscal year 2023 executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$2,575,123
Joseph Hagan total, FY2023
CEO pay percentile vs peers
CEO-to-median pay ratio
99.42%
Say-on-pay support, latest vote
Companies that benchmark against RGLS
1 company names RGLS as a compensation peer

Each company listed discloses RGLS in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named RGLS in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

01

Summary Compensation Table — fiscal year 2023

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Joseph Hagan$615,800$0$88,000$1,528,091$332,532$0$9,900$2,575,123
Chief Executive Officer
Christopher Aker387,700033,300475,845178,34209,9001,085,087
Senior Vice President and General Counsel
Cris Calsada390,000033,300455,674179,40009,9001,068,174
Chief Financial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2023 totalFY2022 totalFY2021 totalΔ FY20222023
Joseph Hagan$2,575,123$1,343,238+1,231,885
Christopher Aker1,085,087651,543+433,544
Cris Calsada1,068,174627,619+440,555

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

04

Outstanding equity awards at fiscal year-end 2023

ExecutiveAwardShares unvestedExercise priceMarket value unvested
Joseph HaganPSU30,000$38,400
Christopher AkerOption43713.1
Christopher AkerPSU11,25014,400
Joseph HaganOption29,99913.1
Joseph HaganOption1,0009.5
Christopher AkerOption7509.5
Christopher AkerOption33,5006.4
Christopher AkerOption4,87515.9
Christopher AkerOption24,9972.6
Christopher AkerOption34,6881.48
Christopher AkerOption360,9381.36
Cris CalsadaOption21,0006.4
Cris CalsadaPSU11,25014,400
Cris CalsadaOption24,9972.6
Cris CalsadaOption31213.1
Christopher AkerOption7,00013.1
Cris CalsadaOption5,00013.1
Joseph HaganOption77,0841.48
Joseph HaganPSU437,500560,000
Christopher AkerPSU131,250168,000
Cris CalsadaPSU125,000160,000
Joseph HaganOption6,5009.5
Joseph HaganOption99,9996.4
Joseph HaganOption1,87513.1
Joseph HaganOption16,25015.9
Joseph HaganOption83,3272.6
Joseph HaganOption1,203,1261.36
Christopher AkerOption2,5009.5
Cris CalsadaOption10,0006.2
Cris CalsadaOption4,05615.9
Cris CalsadaOption24,6881.48
Cris CalsadaOption343,7511.36
05

Incentive-plan design — the Compensation Discussion & Analysis

Our executive compensation program is designed to reward achievement of the specific strategic goals that we believe will advance our business strategy and create long-term value for our stockholders. Consistent with our goal of attracting, motivating and retaining a high-caliber executive team, our executive compensation program is designed to pay for performance.

CEO STI target (% of salary)60%
CEO LTI target (% of salary)
Independent consultantAon/Radford
Clawback policyTrue
Anti-hedgingTrue
Anti-pledgingTrue
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20242024-05-1638,219,586223,13966,21599.42%Passed
20232023-06-1312,652,198334,62832,96497.42%Passed
20222022-06-0974,847,7444,844,630563,72493.92%Passed
20212021-06-1432,643,5801,013,00081,79396.99%Passed
20202020-06-177,956,6012,107,96724,57479.06%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20242024-05-1699.42%a
20232023-06-1397.42%b
20222022-06-0993.92%c

a. Voting standard not stated in the filing.

b. Voting standard not stated in the filing.

c. Voting standard not stated in the filing.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

08

Director compensation — fiscal year 2023

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Stelios Papadopoulos, Ph.DIndependent · Board Chair · Nominating/Governance$84,000$0$47,441$0$131,441
Kathryn J. CollierIndependent · Compensation (Chair)60,000047,4410107,441
William H. Rastetter, Ph.DIndependent · Compensation52,000047,441099,441
Jake R. NunnIndependent · Audit50,000047,441097,441
David Baltimore, Ph.DIndependent · Nominating/Governance (Chair)48,000047,441095,441
Alice S. Huang, Ph.DIndependent · Audit46,000047,441093,441
Pascale WitzIndependent · Audit46,000047,441093,441
Hugh Rosen, M.D., Ph.DIndependent · Nominating/Governance46,000047,441093,441
Joseph P. HaganEmployee director00000
Preston S. Klassen, M.DEmployee director00000
09

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer
Per board meeting fee
Committee chair fees (audit / comp / nom-gov)10,000 / 6,000 / 4,000
Stock ownership guideline
09b

Total cost of the board

ComponentFY2023
Cash retainers and fees$432,000
Equity awards (grant-date value)$0
All other compensation$0
Total cost of the board$432,000

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10

Disclosed peer group — fiscal year 2023

The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.

PULM PulmatrixLCTX Lineage Cell TherapeuticsBCDA BioCardiaATYR aTyr Pharma ContraFectCRVS Corvus PharmaceuticalsRZLT Rezolute TRACON Pharmaceuticals Otonomy CohBar Synlogic
10a

Peer reciprocity

Of the companies Regulus Therapeutics names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.

Pulmatrix (PULM) Lineage Cell Therapeutics (LCTX) BioCardia (BCDA) aTyr Pharma (ATYR)22 Corvus Pharmaceuticals (CRVS) Rezolute (RZLT)

Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including Regulus Therapeutics.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1aTyr Pharma2025Sanjay Shukla$638,977$0$2,595,200$210,862$3,456,253
2Rezolute2025Nevan Charles Elam610,8251,767,204002,851,109
3Regulus Therapeutics2023Joseph Hagan615,80088,0001,528,091332,5322,575,123
Pulmatrixnot in coverage universe
Lineage Cell Therapeuticsnot in coverage universe
BioCardianot in coverage universe
Corvus Pharmaceuticalsnot in coverage universe

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10c

Incentive design against the same peers

CompanyAnnual incentive payoutLong-term vehicle mixPSU measures include TSRCompensation consultant
Regulus Therapeuticsnot disclosednot disclosedNoAon/Radford
aTyr Pharma60% (Committee lowered payout from 75% achievement to 60% given EFZO-FIT study results)%Options 100not disclosedRadford (Aon plc Rewards Solutions)
BioCardianot disclosednot disclosednot disclosednot disclosed
Corvus Pharmaceuticalsnot disclosednot disclosednot disclosednot disclosed
Lineage Cell Therapeuticsnot disclosednot disclosednot disclosednot disclosed
Pulmatrixnot disclosednot disclosednot disclosednot disclosed
Rezolutenot disclosednot disclosednot disclosednot disclosed

Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Joseph HaganDEF 14A2024-04-190001193125-24-102883Section “Summary Compensation Table”. As printed: 2,575,123. Filing ↗machine: t54 · r2 · c27 · span 187482–187491
2Section 01, Christopher AkerDEF 14A2024-04-190001193125-24-102883Section “Summary Compensation Table”. As printed: 1,085,087. Filing ↗machine: t54 · r5 · c27 · span 190505–190514
3Section 01, Cris CalsadaDEF 14A2024-04-190001193125-24-102883Section “Summary Compensation Table”. As printed: 1,068,174. Filing ↗machine: t54 · r8 · c27 · span 193527–193536
4Section 08, Stelios Papadopoulos, Ph.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 131,441. Filing ↗
5Section 08, Kathryn J. CollierDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 107,441. Filing ↗machine: t108 · r3 · c11 · span 346457–346464
6Section 08, William H. Rastetter, Ph.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 99,441. Filing ↗
7Section 08, Jake R. NunnDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 97,441. Filing ↗machine: t108 · r5 · c11 · span 347934–347940
8Section 08, David Baltimore, Ph.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 95,441. Filing ↗
9Section 08, Alice S. Huang, Ph.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 93,441. Filing ↗
10Section 08, Pascale WitzDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 93,441. Filing ↗machine: t108 · r9 · c11 · span 350916–350922
11Section 08, Hugh Rosen, M.D., Ph.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 93,441. Filing ↗
12Section 08, Joseph P. HaganDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 0. Filing ↗
13Section 08, Preston S. Klassen, M.DDEF 14A2024-04-190001193125-24-102883Section “Director Compensation”. As printed: 0. Filing ↗
14Section 06, 2024 voteForm 8-K2024-05-170001193125-24-141703Item 5.07 · say-on-pay result. As reported: 99.42% (votes for as printed: 38,219,586). Filing ↗
15Section 06, 2023 voteForm 8-K2023-06-140001193125-23-166837Item 5.07 · say-on-pay result. As reported: 97.42% (votes for as printed: 12,652,198). Filing ↗
16Section 06, 2022 voteForm 8-K2022-06-130001193125-22-172905Item 5.07 · say-on-pay result. As reported: 93.92%. Filing ↗
17Section 01 trend, Δ column (computed)ComputedcomputedΔ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
18Section 09b board cost (computed)ComputedcomputedCash 432,000 + equity 0 + all other 0 = 432,000, summed across the director compensation table rows.machine: formula: Σ = 432,000
19aTyr Pharma, Section 10b CEO totalDEF 14A2026-03-260001339970-26-000021CEO total compensation as printed in aTyr Pharma's own proxy. As printed: 3,456,253. Filing ↗machine: t11 · r2 · c21 · span 533754–533763
20Rezolute, Section 10b CEO totalDEF 14A2025-10-070001104659-25-097509CEO total compensation as printed in Rezolute's own proxy. As printed: 2,851,109. Filing ↗machine: t83 · r3 · c17 · span 413905–413914
21Regulus Therapeutics (subject), Section 10b CEO totalDEF 14A2024-04-190001193125-24-102883CEO total compensation as printed in Regulus Therapeutics's own proxy. As printed: 2,575,123. Filing ↗machine: t54 · r2 · c27 · span 187482–187491
22Section 10a, aTyr Pharma reciprocityDEF 14A0001339970-26-000021aTyr Pharma's most recent proxy was read; its disclosed peer group does not include Regulus Therapeutics. Filing ↗