Chief Executive Officer · Spyre Therapeutics, Inc. (SYRE)

Cameron Turtle

A named executive officer of Spyre Therapeutics in every fiscal year CompBrief holds from FY2023 to FY2025. Every figure below is printed as the company filed it and cited to the filing it came from.

Velarion Intel: free for 3 days, no card →

Total disclosed compensation, FY2025

$6,707,361

FY2024: $6,960,186

1st of 4 named executive officers at Spyre Therapeutics by FY2025 total.

4 named officers on file for Spyre Therapeutics, FY2025

See an example →

What this number hides

The filing gives the total. Spyre Therapeutics’s full Executive Compensation Report gives every award, the disclosed peer set and what the total leaves out — the pair adds the board’s.

Compensation figures as of the proxy filed April 10, 2026 (DEF 14A). Insider transactions since that proxy, current to 2026-11-06.

Free

Get Cameron Turtle’s full pay file as a PDF — free

More than this page: up to 10 years of Cameron’s pay history, a side-by-side peer comparison, and a one-page board summary — the whole file, yours now and by email.

Also free: The Pay Desk, the weekly executive pay briefing.

Or track Cameron Turtle and every company like it: Velarion Intel, free for 3 days, no card →

Cameron Turtle compensation by year

Spyre Therapeutics Summary Compensation Table · all 3 fiscal years held
In US dollars, as Spyre Therapeutics reports it. Most recent year shaded. Totals are the company’s disclosed totals.
ComponentFY2023FY2024FY2025
Salary$272,850$625,000$665,000
Bonus$141,000$0$0
Stock awards$0$0$0
Option awards$15,500,492$5,914,353$5,552,886
Non-equity incentive$0$412,500$475,475
Pension and deferred compensation$0$0$0
All other$5,203$8,333$14,000
Total$15,919,545$6,960,186$6,707,361

Each year as stated in that year's proxy. A dash means the company reported no figure in that column. Source: Spyre Therapeutics, Inc. DEF 14A filed April 10, 2026, accession 0001636282-26-000039, and prior-year filings. Open the filing on EDGAR.

How this page was built: the Spyre Therapeutics, Inc. filed document, accession 0001636282-26-000039. Every figure is read from that document and cited to the page and table it appears in. Filed April 10, 2026.

$15.9M
$7.0M
$6.7M
FY23
FY24
FY25
SalaryBonusNon-equity incentiveOption awardsAll other

Equity holdings

unvested awards at FY2025 year-end
TypeUnvested unitsValue at year-endExercise price
RSU159,713$5,232,198—
Option709,458—$7.50
Option150,448—$25.86
Option179,209—$10.39
Option285,209—$21.66

Per the Outstanding Equity Awards at Fiscal Year-End table in Spyre Therapeutics, Inc.'s FY2025 proxy; value at the fiscal year-end close, as the company printed it.

Insider transactions since the last proxy

27 Form 4 lines since the FY2025 proxy (filed April 10, 2026)
current to 2026-11-06 · updated nightly
DateTransactionPlanSharesPriceHeld after
2026-10-01Sale10b5-14,990$93.37537,640
2026-10-01Sale10b5-13,989$92.31542,630
2026-10-01Sale10b5-12,683$90.10549,257
2026-10-01Sale10b5-12,638$91.49546,619
2026-10-01Sale10b5-1600$89.14551,940
2026-10-01Sale10b5-1100$93.91537,540
2026-09-01Sale10b5-13,700$88.06552,940
2026-09-01Sale10b5-12,500$86.36565,040

The 8 most recent of 27 lines, each as reported on the Form 4. "10b5-1" marks a trade the filing reports under a pre-arranged trading plan. View every Form 4 filing on EDGAR →

Change-in-control & termination

estimated payments Spyre Therapeutics discloses, by trigger · FY2025
TriggerCash severanceAccelerated equityBenefits continuationTotal as disclosed
Involuntary termination without cause$1,030,750$20,776,931$24,211$21,831,892
Change in control and involuntary termination$1,546,125$31,365,923$36,317$32,948,365
Disability$0$31,365,923$0$31,365,923
Change in control, no termination$0$5,232,198$0$5,232,198
Death$0$31,365,923$0$31,365,923

Per the Potential Payments Upon Termination or Change in Control table in Spyre Therapeutics, Inc.'s FY2025 proxy. Estimates as the company printed them; a dash means it printed no figure.

Spyre Therapeutics’s named executive officers, FY2025

as the company reported each
Named executive officerRoleFY2025 total
Cameron Turtle · this pageChief Executive Officer$6,707,361
Sheldon SloanChief Medical Officer$2,211,805
Heidy King-JonesChief Legal Officer and Corporate Secretary$2,192,045
Scott BurrowsChief Financial Officer$2,192,045

Board service

Spyre Therapeutics board · FY2025

How this board is paid

Company policy: Spyre Therapeutics pays directors a $40,000 cash retainer and $350,000 in equity. As stated in Spyre Therapeutics's FY2025 proxy.

The full Spyre Therapeutics compensation record

free company brief

This page is one person within Spyre Therapeutics's record. The company brief lists every named executive, each linking to their own page.

Peer companies

named in the Spyre Therapeutics proxy · each links to its own free brief

Compensation, the day it’s disclosed

The CompBrief Daily Digest lists the newest executive and director compensation disclosures as companies file them. Or order Spyre Therapeutics's full Executive Compensation Report with peer benchmarking.

How this record is built

Every figure on this page is one figure from a public SEC filing, printed as the filing states it and cited to the document. Compensation totals are Spyre Therapeutics's own disclosed totals, not summed by Velarion. Insider transactions are read from Form 4 filings and cover every line filed since the most recent proxy. Nothing is estimated by Velarion; where the company does not disclose a value the cell reads "—", and a section appears only where the company discloses the data. Corrections: records@velarion.ai.

Order SYRE

Add the email the receipt and the PDF go to, then press the report you want. Each button opens its own card payment on Stripe.

Receipt, invoice, and report delivery. Guest checkout, no account required, secure payment by Stripe.

Cameron Turtle's compensation dossier