President and Chief Executive Officer · Praxis Precision Medicines, Inc. (PRAX)

Marcio Souza

A named executive officer of Praxis Precision Medicines in every fiscal year CompBrief holds from FY2020 to FY2025. Every figure below is printed as the company filed it and cited to the filing it came from.

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Total disclosed compensation, FY2025

$8,708,648

FY2024: $13,427,668

1st of 3 named executive officers at Praxis Precision Medicines by FY2025 total.

3 named officers on file for Praxis Precision Medicines, FY2025

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What this number hides

The filing gives the total. Praxis Precision Medicines’s full Executive Compensation Report gives every award, the disclosed peer set and what the total leaves out — the pair adds the board’s.

Compensation figures as of the proxy filed April 30, 2026 (DEF 14A).

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Marcio Souza compensation by year

Praxis Precision Medicines Summary Compensation Table · all 6 fiscal years held
In US dollars, as Praxis Precision Medicines reports it. Most recent year shaded. Totals are the company’s disclosed totals.
ComponentFY2020FY2021FY2022FY2023FY2024FY2025
Salary$385,417$570,834$625,000$625,000$640,000$659,200
Bonus$24,000$0$0$0$0$0
Stock awards$0$2,773,584$1,340,140$0$0$2,368,125
Option awards$10,301,160$6,883,800$3,649,420$941,364$11,791,710$3,691,125
Non-equity incentive$1,001,000$646,875$375,000$515,625$960,000$1,483,200
Pension and deferred compensation$0$0$0$0$0$0
All other$30,382$30,727$38,518$38,523$35,958$506,998
Total$11,741,959$10,905,820$6,028,078$2,120,512$13,427,668$8,708,648

Each year as stated in that year's proxy. A dash means the company reported no figure in that column. Source: Praxis Precision Medicines, Inc. DEF 14A filed April 30, 2026, accession 0001689548-26-000039, and prior-year filings. Open the filing on EDGAR.

How this page was built: the Praxis Precision Medicines, Inc. filed document, accession 0001689548-26-000039. Every figure is read from that document and cited to the page and table it appears in. Filed April 30, 2026.

$11.7M
$10.9M
$6.0M
$2.1M
$13.4M
$8.7M
FY20
FY21
FY22
FY23
FY24
FY25
SalaryBonusNon-equity incentiveStock awardsOption awardsAll other

Equity holdings

unvested awards at FY2025 year-end
TypeUnvested unitsValue at year-endExercise price
RSU37,500$11,052,750—
RSU1,233$363,414—
Option358—$271.65
Option854—$31.80
Option7,680—$44.40
Option26,042—$43.37
Option92,501—$56.94
Option75,000—$63.15

Per the Outstanding Equity Awards at Fiscal Year-End table in Praxis Precision Medicines, Inc.'s FY2025 proxy; value at the fiscal year-end close, as the company printed it.

Change-in-control & termination

estimated payments Praxis Precision Medicines discloses, by trigger · FY2025
TriggerCash severanceAccelerated equityBenefits continuationTotal as disclosed
Involuntary termination without cause$659,200—$37,174$2,179,574
Change in control and involuntary termination$2,018,800$59,483,758$55,761$62,052,719

Per the Potential Payments Upon Termination or Change in Control table in Praxis Precision Medicines, Inc.'s FY2025 proxy. Estimates as the company printed them; a dash means it printed no figure.

Praxis Precision Medicines’s named executive officers, FY2025

as the company reported each
Named executive officerRoleFY2025 total
Marcio Souza · this pagePresident and Chief Executive Officer$8,708,648
Timothy KellyChief Financial Officer$3,201,194
Alex NemiroffGeneral Counsel$2,843,783

Board service

Praxis Precision Medicines board · FY2021–FY2025

How this board is paid

Company policy: Praxis Precision Medicines pays directors a $40,000 cash retainer. As stated in Praxis Precision Medicines's FY2025 proxy.

The full Praxis Precision Medicines compensation record

free company brief

This page is one person within Praxis Precision Medicines's record. The company brief lists every named executive, each linking to their own page.

Peer companies

named in the Praxis Precision Medicines proxy · each links to its own free brief

Compensation, the day it’s disclosed

The CompBrief Daily Digest lists the newest executive and director compensation disclosures as companies file them. Or order Praxis Precision Medicines's full Executive Compensation Report with peer benchmarking.

How this record is built

Every figure on this page is one figure from a public SEC filing, printed as the filing states it and cited to the document. Compensation totals are Praxis Precision Medicines's own disclosed totals, not summed by Velarion. Insider transactions are read from Form 4 filings and cover every line filed since the most recent proxy. Nothing is estimated by Velarion; where the company does not disclose a value the cell reads "—", and a section appears only where the company discloses the data. Corrections: records@velarion.ai.

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Marcio Souza's compensation dossier