Fiscal year 2025 executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.
Each company listed discloses AGIO in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named AGIO in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.
| Named executive officer | Salary | Bonus | Stock awards | Option awards | Non-equity incentive | Pension / NQDC | All other | Total |
|---|---|---|---|---|---|---|---|---|
| Brian Goff | $846,864 | — | $1,291,680 | $2,627,252 | $592,804 | — | $11,789 | $5,370,389 |
| Chief Executive Officer | ||||||||
| Krishnan Viswanadhan | 433,125 | 250,000 | 824,985 | 1,048,532 | 236,250 | — | 12,134 | 2,805,026 |
| Chief Corporate Development & Strategy Officer | ||||||||
| Cecilia Jones | 535,085 | — | 924,379 | 802,008 | 240,789 | — | 15,961 | 2,518,222 |
| Chief Financial Officer | ||||||||
| James Burns | 527,275 | — | 786,898 | 802,008 | 237,274 | — | 15,961 | 2,369,416 |
| Chief Legal Officer | ||||||||
| Sarah Gheuens | 601,060 | — | 397,440 | 802,008 | 270,478 | — | 15,694 | 2,086,680 |
| Chief Medical Officer, Head of Research & Development | ||||||||
A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.
| Named executive officer | FY2025 total | FY2024 total | FY2023 total | Δ FY2024→2025 |
|---|---|---|---|---|
| Brian Goff | $5,370,389 | $6,776,359 | $3,416,453 | −1,405,970 |
| Krishnan Viswanadhan | 2,805,026 | — | — | — |
| Cecilia Jones | 2,518,222 | 2,419,349 | 1,208,784 | +98,873 |
| James Burns | 2,369,416 | 2,432,507 | 1,934,540 | −63,091 |
| Sarah Gheuens | 2,086,680 | 2,544,347 | 2,870,159 | −457,667 |
Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.
Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Dividend-equivalent accruals | 2026-06-13 | — | 3,952 | — | — | 2 insiders, 2 accrual rows | ||
| Adams Catherine Owen | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | A | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | D | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 8,375 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 4,007 | 38 | 150,503 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | A | 8,375 | 0 | 0 | Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-07-08 | A | 1,447 | 0 | 0 | Common | Form 4 ↗ |
| Dividend-equivalent accruals | 2026-07-08 | — | 1,447 | — | — | 1 insider, 1 accrual row | ||
Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Jeffrey Capello | Director | 2026-06-13 | D | 1,976 | $0 | $0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-13 | D | 1,976 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | A | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | D | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 8,375 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 4,007 | 38 | 150,503 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | A | 8,375 | 0 | 0 | Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-07-08 | A | 1,447 | 0 | 0 | Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-07-08 | D | 1,447 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Executive | Award | Grant date | Threshold | Target | Granted | Maximum | Grant-date fair value |
|---|---|---|---|---|---|---|---|
| Krishnan Viswanadhan | OPTION | 2025-03-05 | — | — | 55,374 | — | $1,048,532 |
| James Burns | OPTION | 2025-03-01 | — | — | 43,500 | — | 802,008 |
| Brian Goff | OPTION | 2025-03-01 | — | — | 142,500 | — | 2,627,252 |
| Cecilia Jones | OPTION | 2025-03-01 | — | — | 43,500 | — | 802,008 |
| Sarah Gheuens | OPTION | 2025-03-01 | — | — | 43,500 | — | 802,008 |
| Named executive officer | Time-vested (RSU) | Performance-vested (PSU) | Options / SARs | % performance-vested |
|---|---|---|---|---|
| Krishnan Viswanadhan | $0 | $0 | $1,048,532 | 0.0% |
| James Burns | 0 | 0 | 802,008 | 0.0% |
| Brian Goff | 0 | 0 | 2,627,252 | 0.0% |
| Cecilia Jones | 0 | 0 | 802,008 | 0.0% |
| Sarah Gheuens | 0 | 0 | 802,008 | 0.0% |
% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.
| Executive | Award | Shares unvested | Exercise price | Market value unvested |
|---|---|---|---|---|
| Brian Goff | Option | 93,520 | 29.38 | — |
| Sarah Gheuens | RSU | 24,300 | — | 661,446 |
| James Burns | Option | 2,565 | 32.2 | — |
| Sarah Gheuens | RSU | 4,000 | — | 108,880 |
| Brian Goff | RSU | 8,500 | — | 231,370 |
| Sarah Gheuens | RSU | 8,375 | — | 227,968 |
| Cecilia Jones | Option | 6,882 | 25.01 | — |
| Cecilia Jones | RSU | 2,000 | — | 54,440 |
| Cecilia Jones | Option | 43,500 | 33.12 | — |
| Cecilia Jones | RSU | 11,333 | — | 308,484 |
| Sarah Gheuens | RSU | 11,333 | — | 308,484 |
| Sarah Gheuens | Option | 43,500 | 33.12 | — |
| James Burns | RSU | 11,333 | — | 308,484 |
| Cecilia Jones | Option | 33,750 | 32.27 | — |
| James Burns | RSU | 4,000 | — | 108,880 |
| James Burns | Option | 33,750 | 32.27 | — |
| Brian Goff | Option | 29,535 | 25.01 | — |
| Sarah Gheuens | Option | 13,755 | 25.01 | — |
| Sarah Gheuens | Option | 2,565 | 32.2 | — |
| James Burns | Option | 13,755 | 25.01 | — |
| James Burns | Option | 43,500 | 33.12 | — |
| Sarah Gheuens | Option | 33,750 | 32.27 | — |
| Cecilia Jones | RSU | 27,910 | — | 759,710 |
| Brian Goff | RSU | 39,000 | — | 1,061,580 |
| Brian Goff | RSU | 36,000 | — | 979,920 |
| James Burns | RSU | 23,759 | — | 646,720 |
| Sarah Gheuens | RSU | 12,000 | — | 326,640 |
| Brian Goff | Option | 109,971 | 32.27 | — |
| Brian Goff | Option | 142,500 | 33.12 | — |
| Cecilia Jones | Option | 22,203 | 27.88 | — |
| Sarah Gheuens | Option | 55,374 | 33.95 | — |
Our compensation & people committee believes that the most effective compensation program is one that rewards sustainable value creation for stockholders, through the delivery of strong company performance, as well as tangible progress toward achieving our mission to improve the lives of patients.
| CEO STI target (% of salary) | 70% |
|---|---|
| CEO LTI target (% of salary) | — |
| Independent consultant | Aon |
| Clawback policy | true |
| Anti-hedging | true |
| Anti-pledging | True |
| Meeting year | Meeting date | For | Against | Abstain | Support | Outcome |
|---|---|---|---|---|---|---|
| 2026 | 2026-06-18 | 43,396,045 | 1,086,059 | 1,606,976 | 97.56% | Passed |
| 2025 | 2025-06-18 | 46,843,926 | 3,024,905 | 16,430 | 93.93% | Passed |
| 2024 | 2024-06-20 | 47,985,871 | 3,120,093 | 13,404 | 93.89% | Passed |
| 2023 | 2023-06-13 | 46,289,192 | 4,630,627 | 9,604 | 90.91% | Passed |
| 2022 | 2022-06-21 | 45,023,409 | 4,523,606 | 9,007 | 90.87% | Passed |
| 2021 | 2021-05-20 | 58,442,174 | 6,173,957 | 7,427 | 90.45% | Passed |
Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.
| Meeting year | Meeting date | Approval — company's computation |
|---|---|---|
| 2026 | 2026-06-18 | 97.56%a |
| 2025 | 2025-06-18 | 93.93%b |
| 2024 | 2024-06-20 | 93.89%c |
a. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
b. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
c. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.
| Ratio (CEO : median employee) | 18 : 1 |
|---|---|
| CEO total compensation | $5,370,389 |
| Median employee compensation | $303,140 |
| Director | Cash fees | Stock awards | Option awards | Non-equity incentive | All other | Total |
|---|---|---|---|---|---|---|
| Jay BackstromIndependent · Science and Technology · Newly elected | $27,656 | $157,491 | $472,002 | $0 | $0 | $657,149 |
| Kaye FosterIndependent · Lead Independent Director · Compensation & People · Nominating and Corporate Governance (Chair) | 98,750 | 99,968 | 299,689 | 0 | 0 | 498,407 |
| Jacqualyn A. FouseIndependent · Board Chair · Science and Technology | 92,500 | 99,968 | 299,689 | 0 | 0 | 492,157 |
| Jeffrey CapelloIndependent · Audit (Chair) | 70,000 | 99,968 | 299,689 | 0 | 0 | 469,657 |
| David ScaddenIndependent · Nominating and Corporate Governance · Science and Technology (Chair) | 70,000 | 99,968 | 299,689 | 0 | 0 | 469,657 |
| Rahul BallalIndependent · Audit · Science and Technology | 67,500 | 99,968 | 299,689 | 0 | 0 | 467,157 |
| Cynthia SmithIndependent · Compensation & People (Chair) | 67,500 | 99,968 | 299,689 | 0 | 0 | 467,157 |
| Maykin HoIndependent · Audit · Nominating and Corporate Governance | 65,000 | 99,968 | 299,689 | 0 | 0 | 464,657 |
| Catherine Owen AdamsIndependent · Compensation & People | 58,750 | 99,968 | 299,689 | 0 | 0 | 458,407 |
| David P. SchenkeinIndependent · Departed during FY | 9,424 | — | — | 0 | 0 | 9,424 |
| Brian GoffEmployee director | 0 | 0 | 0 | — | 0 | 0 |
| Annual cash retainer | $50,000 |
|---|---|
| Annual equity retainer | $400,000 |
| Per board meeting fee | — |
| Committee chair fees (audit / comp / nom-gov) | 20,000 / 17,500 / 10,000 |
| Stock ownership guideline | 3x annual cash retainer |
| Component | FY2025 |
|---|---|
| Cash retainers and fees | $627,080 |
| Equity awards (grant-date value) | $957,235 |
| All other compensation | $0 |
| Total cost of the board | $1,584,315 |
Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.
The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.
Of the companies Agios Pharmaceuticals, Inc. names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.
Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including Agios Pharmaceuticals, Inc..
Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.
| Rank | Company | FY | Chief executive | Salary | Stock awards | Option awards | Non-equity incentive | Total |
|---|---|---|---|---|---|---|---|---|
| 1 | Rhythm Pharmaceuticals, Inc. | 2025 | David Meeker | $807,692 | $8,274,785 | $7,688,560 | $759,488 | $17,544,525 |
| 2 | SpringWorks Therapeutics, Inc. | 2024 | Saqib Islam | 760,000 | 7,899,760 | 6,689,100 | 798,000 | 16,153,317 |
| 3 | Blueprint Medicines Corporation | 2024 | Kathryn Haviland | 821,363 | 7,472,480 | 4,315,144 | 854,217 | 13,477,004 |
| 4 | BioCryst Pharmaceuticals, Inc. | 2025 | Jon Stonehouse | 728,466 | 0 | 11,132,458 | 1,052,633 | 12,951,082 |
| 5 | Crinetics Pharmaceuticals, Inc. | 2025 | R. Scott Struthers | 718,500 | 3,280,540 | 7,160,564 | 462,355 | 11,628,959 |
| 6 | Ultragenyx Pharmaceutical Inc. | 2025 | Emil Kakkis | 861,100 | 8,364,938 | 1,847,356 | 299,663 | 11,405,535 |
| 7 | Apellis Pharmaceuticals, Inc. | 2024 | Cedric Francois | 793,193 | 4,779,832 | 4,787,768 | 0 | 10,957,451 |
| 8 | Mirum Pharmaceuticals, Inc. | 2025 | Christopher Peetz | 755,000 | 3,683,904 | 4,931,320 | 1,057,000 | 10,441,224 |
| 9 | Arcus Biosciences, Inc. | 2025 | Terry Rosen | 775,000 | 2,199,450 | 6,008,860 | 658,750 | 9,656,813 |
| 10 | Amicus Therapeutics, Inc. | 2024 | Bradley Campbell | 767,308 | 4,990,365 | 2,105,627 | 0 | 8,526,943 |
| 11 | Travere Therapeutics, Inc. | 2025 | Eric Dube | 854,250 | 3,314,520 | 3,309,384 | 964,125 | 8,457,151 |
| 12 | ACADIA Pharmaceuticals Inc. | 2025 | Catherine Owen Adams | 930,000 | 3,240,558 | 3,234,797 | 818,559 | 8,256,518 |
| 13 | Sage Therapeutics, Inc. | 2024 | Barry Greene | 830,712 | 3,164,364 | 2,669,263 | 431,970 | 7,112,589 |
| 14 | Agios Pharmaceuticals, Inc. | 2025 | Brian Goff | 846,864 | 1,291,680 | 2,627,252 | 592,804 | 5,370,389 |
| 15 | Intellia Therapeutics, Inc. | 2025 | John Leonard | 708,000 | 2,443,920 | 1,356,320 | 0 | 5,063,899 |
Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.
| Company | Annual incentive payout | Long-term vehicle mix | PSU measures include TSR | Compensation consultant |
|---|---|---|---|---|
| Agios Pharmaceuticals, Inc. | 100% | Options 40 · PSU 40 · RSU 20 | No | Aon |
| ACADIA Pharmaceuticals Inc. | 110% | Options 50 · PSU 25 · RSU 25 | Yes | FW Cook |
| Amicus Therapeutics, Inc. | 108% | Options 33 · RSU 33 · PSU 33 | Yes — TSR Goal | Pay Governance |
| Apellis Pharmaceuticals, Inc. | 90.74% | not disclosed | Yes — Total Shareholder Return (TSR) relative to NASDAQ Biotechnology Index | Pay Governance |
| Arcus Biosciences, Inc. | 100% | Options 67 · RSU 33 | not disclosed | Radford |
| BioCryst Pharmaceuticals, Inc. | 170% | not disclosed | not disclosed | Aon Human Capital Solutions (division of Aon plc) |
| Blueprint Medicines Corporation | 130% | RSU 37 · Options 32 · PSU 31 | Yes — Relative Total Stockholder Return (rTSR) | Aon (Human Capital Solutions practice, formerly Radford) |
| Crinetics Pharmaceuticals, Inc. | not disclosed | Options 70 · RSU 30 | not disclosed | Pearl Meyer |
| Intellia Therapeutics, Inc. | 115% | Options 40 · RSU 40 · PSU 20 | Yes — TSR relative to the Nasdaq Biotechnology Index | Alpine Rewards, LLC |
| Mirum Pharmaceuticals, Inc. | 200% | not disclosed | No | Alpine Rewards |
| Rhythm Pharmaceuticals, Inc. | 120% | Options 50 · RSU 50 | No | Pay Governance LLC |
| Sage Therapeutics, Inc. | 80% | not disclosed | Yes — TSR milestones / Relative TSR vs. Nasdaq Biotechnology Index | Alpine Rewards |
| SpringWorks Therapeutics, Inc. | 140% | not disclosed | Yes — Relative Total Shareholder Return (TSR) | Aon plc (Human Capital Solutions practice) |
| Travere Therapeutics, Inc. | 150% | not disclosed | No | Aon |
| Ultragenyx Pharmaceutical Inc. | 44% | PSU 60 · RSU 20 · Options 20 | Yes — Relative TSR | Aon's Human Capital Solutions Practice |
Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.
Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.
Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.
| # | Supports | Document | Filed | Accession | Location in document |
|---|---|---|---|---|---|
| 1 | Section 01, Brian Goff | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Summary Compensation Table”. As printed: 5,370,389. Filing ↗machine: r2 · c31 · span 613185–613194 |
| 2 | Section 01, Krishnan Viswanadhan | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Summary Compensation Table”. As printed: 2,805,026. Filing ↗machine: t217 · r14 · c31 · span 642579–642588 |
| 3 | Section 01, Cecilia Jones | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Summary Compensation Table”. As printed: 2,518,222. Filing ↗machine: r5 · c31 · span 620543–620552 |
| 4 | Section 01, James Burns | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Summary Compensation Table”. As printed: 2,369,416. Filing ↗machine: r8 · c31 · span 627870–627879 |
| 5 | Section 01, Sarah Gheuens | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Summary Compensation Table”. As printed: 2,086,680. Filing ↗machine: r11 · c31 · span 635233–635242 |
| 6 | Section 03, Krishnan Viswanadhan OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t222 · r24 · c47 · span 724046–724055 |
| 7 | Section 03, James Burns OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t217 · r8 · c19 · span 627208–627215 |
| 8 | Section 03, Brian Goff OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t222 · r6 · c47 · span 672554–672563 |
| 9 | Section 03, Cecilia Jones OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t222 · r11 · c47 · span 686456–686463 |
| 10 | Section 03, Sarah Gheuens OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t222 · r20 · c47 · span 712267–712274 |
| 11 | Section 07, pay ratio | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “CEO Pay Ratio”. As printed: 18 : 1. Filing ↗machine: span 961005–961007 |
| 12 | Section 08, Jay Backstrom | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 657,149. Filing ↗machine: t112 · r2 · c19 · span 335199–335206 |
| 13 | Section 08, Kaye Foster | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 498,407. Filing ↗machine: t112 · r5 · c19 · span 339481–339488 |
| 14 | Section 08, Jacqualyn A. Fouse | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 492,157. Filing ↗machine: t112 · r6 · c19 · span 340932–340939 |
| 15 | Section 08, Jeffrey Capello | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 469,657. Filing ↗machine: t112 · r4 · c19 · span 338066–338073 |
| 16 | Section 08, David Scadden | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 469,657. Filing ↗machine: t112 · r9 · c19 · span 345224–345231 |
| 17 | Section 08, Rahul Ballal | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 467,157. Filing ↗machine: t112 · r3 · c19 · span 336622–336629 |
| 18 | Section 08, Cynthia Smith | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 467,157. Filing ↗machine: t112 · r11 · c19 · span 348171–348178 |
| 19 | Section 08, Maykin Ho | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 464,657. Filing ↗machine: t112 · r7 · c19 · span 342352–342359 |
| 20 | Section 08, Catherine Owen Adams | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 458,407. Filing ↗machine: t112 · r8 · c19 · span 343801–343808 |
| 21 | Section 08, David P. Schenkein | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 9,424. Filing ↗machine: t112 · r10 · c3 · span 345760–345765 |
| 22 | Section 08, Brian Goff | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 0. Filing ↗ |
| 23 | Section 02, Jeffrey Capello 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000075 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 24 | Section 02, Adams Catherine Owen 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000077 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 25 | Section 02, Jeffrey Capello 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000075 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 26 | Section 02, Adams Catherine Owen 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000077 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 27 | Section 02, Brian Goff 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000089 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 28 | Section 02, James Burns 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000087 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 29 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 30 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 31 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 32 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 33 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 34 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 35 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 36 | Section 02, Jay Backstrom 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000079 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 37 | Section 02, James Burns 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000087 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 38 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 39 | Section 02, Cecilia Jones 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000083 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 40 | Section 02, Tsveta Milanova 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000081 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 41 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 42 | Section 02, Sarah Gheuens 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000085 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 43 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 44 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 45 | Section 02, Krishnan Viswanadhan 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000091 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 46 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 47 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 48 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 49 | Section 02, Tsveta Milanova 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000081 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 50 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 51 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 52 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 53 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 54 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 55 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 56 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 57 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 58 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 59 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 60 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 61 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 62 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 63 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 64 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 65 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 66 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 67 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 68 | Section 02, Krishnan Viswanadhan 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000091 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 69 | Section 02, Brian Goff 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000089 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 70 | Section 02, Sarah Gheuens 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000085 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 71 | Section 02, Cecilia Jones 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000083 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 72 | Section 02, Jay Backstrom 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000079 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 73 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 74 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 75 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 76 | Section 02, Jay Backstrom 2026-07-08 | Form 4 | 2026-07-10 | 0001439222-26-000112 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 77 | Section 02, Jay Backstrom 2026-07-08 | Form 4 | 2026-07-10 | 0001439222-26-000112 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 78 | Section 06, 2026 vote | Form 8-K | 2026-06-18 | 0001193125-26-275879 | Item 5.07 · say-on-pay result. As reported: 97.56% (votes for as printed: 43,396,045). Filing ↗ |
| 79 | Section 06, 2025 vote | Form 8-K | 2025-06-18 | 0001193125-25-142745 | Item 5.07 · say-on-pay result. As reported: 93.93% (votes for as printed: 46,843,926). Filing ↗ |
| 80 | Section 06, 2024 vote | Form 8-K | 2024-06-20 | 0001193125-24-164555 | Item 5.07 · say-on-pay result. As reported: 93.89% (votes for as printed: 47,985,871). Filing ↗ |
| 81 | Section 01 trend, Δ column (computed) | Computed | — | computed | Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1) |
| 82 | Section 03b vehicle mix (computed) | Computed | — | computed | RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio |
| 83 | Section 09b board cost (computed) | Computed | — | computed | Cash 627,080 + equity 957,235 + all other 0 = 1,584,315, summed across the director compensation table rows.machine: formula: Σ = 1,584,315 |
| 84 | Rhythm Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-29 | 0001628280-26-028375 | CEO total compensation as printed in Rhythm Pharmaceuticals, Inc.'s own proxy. As printed: 17,544,525. Filing ↗machine: r2 · c42 · span 513064–513074 |
| 85 | SpringWorks Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-04 | 0001104659-25-032187 | CEO total compensation as printed in SpringWorks Therapeutics, Inc.'s own proxy. As printed: 16,153,317. Filing ↗machine: t23 · r1 · c44 · span 623184–623194 |
| 86 | Blueprint Medicines Corporation, Section 10b CEO total | DEF 14A | 2025-04-24 | 0001558370-25-005415 | CEO total compensation as printed in Blueprint Medicines Corporation's own proxy. As printed: 13,477,004. Filing ↗machine: t150 · r5 · c14 · span 1101152–1101162 |
| 87 | BioCryst Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-23 | 0001628280-26-026822 | CEO total compensation as printed in BioCryst Pharmaceuticals, Inc.'s own proxy. As printed: 12,951,082. Filing ↗machine: span 512256–512266 |
| 88 | Crinetics Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-29 | 0001658247-26-000030 | CEO total compensation as printed in Crinetics Pharmaceuticals, Inc.'s own proxy. As printed: 11,628,959. Filing ↗machine: r2 · c48 · span 589450–589460 |
| 89 | Ultragenyx Pharmaceutical Inc., Section 10b CEO total | DEF 14A | 2026-03-27 | 0001308179-26-000174 | CEO total compensation as printed in Ultragenyx Pharmaceutical Inc.'s own proxy. As printed: 11,405,535. Filing ↗machine: span 668997–669007 |
| 90 | Apellis Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2025-04-23 | 0000950170-25-056966 | CEO total compensation as printed in Apellis Pharmaceuticals, Inc.'s own proxy. As printed: 10,957,451. Filing ↗machine: r2 · c25 · span 951555–951565 |
| 91 | Mirum Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-23 | 0001759425-26-000027 | CEO total compensation as printed in Mirum Pharmaceuticals, Inc.'s own proxy. As printed: 10,441,224. Filing ↗machine: r2 · c21 · span 580200–580210 |
| 92 | Arcus Biosciences, Inc., Section 10b CEO total | DEF 14A | 2026-04-21 | 0001724521-26-000025 | CEO total compensation as printed in Arcus Biosciences, Inc.'s own proxy. As printed: 9,656,813. Filing ↗machine: r2 · c48 · span 403740–403749 |
| 93 | Amicus Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-24 | 0001140361-25-015479 | CEO total compensation as printed in Amicus Therapeutics, Inc.'s own proxy. As printed: 8,526,943. Filing ↗machine: r2 · c25 · span 736127–736137 |
| 94 | Travere Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-06 | 0001438533-26-000027 | CEO total compensation as printed in Travere Therapeutics, Inc.'s own proxy. As printed: 8,457,151. Filing ↗machine: span 558514–558523 |
| 95 | ACADIA Pharmaceuticals Inc., Section 10b CEO total | DEF 14A | 2026-04-24 | 0001193125-26-174163 | CEO total compensation as printed in ACADIA Pharmaceuticals Inc.'s own proxy. As printed: 8,256,518. Filing ↗machine: t33 · span 1170878–1170887 |
| 96 | Sage Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-24 | 0000950170-25-058060 | CEO total compensation as printed in Sage Therapeutics, Inc.'s own proxy. As printed: 7,112,589. Filing ↗machine: r4 · c28 · span 1143784–1143793 |
| 97 | Agios Pharmaceuticals, Inc. (subject), Section 10b CEO total | DEF 14A | 2026-04-24 | 0001193125-26-177086 | CEO total compensation as printed in Agios Pharmaceuticals, Inc.'s own proxy. As printed: 5,370,389. Filing ↗machine: r2 · c31 · span 613185–613194 |
| 98 | Intellia Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-30 | 0001193125-26-197283 | CEO total compensation as printed in Intellia Therapeutics, Inc.'s own proxy. As printed: 5,063,899. Filing ↗machine: r2 · c25 · span 749290–749299 |
| 99 | Section 10a, Mirum Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001759425-26-000027 | Mirum Pharmaceuticals, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 100 | Section 10a, SpringWorks Therapeutics, Inc. reciprocity | DEF 14A | — | 0001104659-25-032187 | SpringWorks Therapeutics, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 101 | Section 10a, Rhythm Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001628280-26-028375 | Rhythm Pharmaceuticals, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 102 | Section 10a, Amicus Therapeutics, Inc. reciprocity | DEF 14A | — | 0001140361-25-015479 | Amicus Therapeutics, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 103 | Section 10a, Apellis Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0000950170-25-056966 | Apellis Pharmaceuticals, Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 104 | Section 10a, Travere Therapeutics, Inc. reciprocity | DEF 14A | — | 0001438533-26-000027 | Travere Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 105 | Section 10a, Blueprint Medicines Corporation reciprocity | DEF 14A | — | 0001558370-25-005415 | Blueprint Medicines Corporation's most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 106 | Section 10a, Crinetics Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001658247-26-000030 | Crinetics Pharmaceuticals, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 107 | Section 10a, Intellia Therapeutics, Inc. reciprocity | DEF 14A | — | 0001193125-26-197283 | Intellia Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 108 | Section 10a, Ultragenyx Pharmaceutical Inc. reciprocity | DEF 14A | — | 0001308179-26-000174 | Ultragenyx Pharmaceutical Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 109 | Section 10a, Sage Therapeutics, Inc. reciprocity | DEF 14A | — | 0000950170-25-058060 | Sage Therapeutics, Inc. names Agios Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 110 | Section 10a, ACADIA Pharmaceuticals Inc. reciprocity | DEF 14A | — | 0001193125-26-174163 | ACADIA Pharmaceuticals Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |
| 111 | Section 10a, BioCryst Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001628280-26-026822 | BioCryst Pharmaceuticals, Inc.'s most recent proxy was read; its disclosed peer group does not include Agios Pharmaceuticals, Inc.. Filing ↗ |