CEO Brian Goff was paid $5,370,389 in fiscal year 2025, ↓ down 20.7% from fiscal year 2024, the 6th percentile of its disclosed peer group (SEC filing 0001193125-26-177086 ↗): executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.
$5,370,389 ↓ Brian Goff total, FY2025 | 6th CEO pay percentile vs peers | 18:1 CEO-to-median pay ratio | 97.56% Say-on-pay support, latest vote |
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AGIO's next annual pay disclosure, estimated April 24, 2027.est. Filing ↗
Page 2 of 36 of the AGIOS PHARMACEUTICALS, INC. Executive Compensation Report, as it is delivered: Executive Summary.
That is page 2 of 36 of the full Executive Compensation Report, shown as it is delivered. The rest:
Every figure above cites the filing it came from (accession 0001193125-26-177086, filed 2026-08-06) — see the source register, §11.
| Named executive officer | Salary | Bonus | Stock awards | Option awards | Non-equity incentive | Pension / NQDC | All other | Total |
|---|---|---|---|---|---|---|---|---|
| Brian Goff | $846,864 | $0 | $1,291,680 | $2,627,252 | $592,804 | $0 | $11,789 | $5,370,389 |
| Chief Executive Officer | ||||||||
| Krishnan Viswanadhan | 433,125 | 250,000 | 824,985 | 1,048,532 | 236,250 | 0 | 12,134 | 2,805,026 |
| Chief Corporate Development & Strategy Officer | ||||||||
| Cecilia Jones | 535,085 | 0 | 924,379 | 802,008 | 240,789 | 0 | 15,961 | 2,518,222 |
| Chief Financial Officer | ||||||||
| James Burns | 527,275 | 0 | 786,898 | 802,008 | 237,274 | 0 | 15,961 | 2,369,416 |
| Chief Legal Officer | ||||||||
| Sarah Gheuens | 601,060 | 0 | 397,440 | 802,008 | 270,478 | 0 | 15,694 | 2,086,680 |
| Chief Medical Officer, Head of Research & Development | ||||||||
A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.
| Named executive officer | FY2025 total | FY2024 total | FY2023 total | Δ FY2024→2025 |
|---|---|---|---|---|
| Brian Goff | $5,370,389 | $6,776,359 | $3,416,453 | ↓ −1,405,970 |
| Krishnan Viswanadhan | 2,805,026 | — | — | — |
| Cecilia Jones | 2,518,222 | 2,419,349 | 1,208,784 | ↑ +98,873 |
| James Burns | 2,369,416 | 2,432,507 | 1,934,540 | ↓ −63,091 |
| Sarah Gheuens | 2,086,680 | 2,544,347 | 2,870,159 | ↓ −457,667 |
Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.
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$5,370,389 Brian Goff total, FY2025
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Data as of August 6, 2026 · Source: 0001193125-26-177086 · Velarion Executive Compensation Database, deposited on Zenodo (doi:10.5281/zenodo.22283855).
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Each company listed discloses AGIO in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named AGIO in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.
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One page per officer: the same table above, read for one person at a time — his own figure and every fiscal year the register holds.
| Executive | Role | FY2025 total |
|---|---|---|
| Brian Goff | CEO | $5,370,389 |
| Cecilia Jones | CFO | $2,518,222 |
| James Burns | General Counsel | $2,369,416 |
| Krishnan Viswanadhan | Executive | $2,805,026 |
| Sarah Gheuens | Executive | $2,086,680 |
One page per director: the seat, the committees and the fee table, read for one person at a time.
| Director | Role | FY2025 total |
|---|---|---|
| Catherine Owen Adams | Independent Director | $458,407 |
| Cynthia Smith | Independent Director | $467,157 |
| David P. Schenkein | Former director (through FY2025) | $9,424 |
| David Scadden | Independent Director | $469,657 |
| Jacqualyn A. Fouse | Independent Director | $492,157 |
| Jay Backstrom | Independent Director | $657,149 |
| Jeffrey Capello | Independent Director | $469,657 |
| Kaye Foster | Independent Director | $498,407 |
| Maykin Ho | Independent Director | $464,657 |
| Rahul Ballal | Independent Director | $467,157 |
Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Dividend-equivalent accruals | 2026-06-13 | — | 3,952 | — | — | 2 insiders, 2 accrual rows | ||
| Adams Catherine Owen | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | A | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | D | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | A | 8,375 | 0 | 0 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 8,375 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 4,007 | 38 | 150,503 | Common | Form 4 ↗ |
| Dividend-equivalent accruals | 2026-07-08 | — | 1,447 | — | — | 1 insider, 1 accrual row | ||
| Jay Backstrom | Director | 2026-07-08 | A | 1,447 | 0 | 0 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-08-04 | D | 30,000 | 30 | 914,400 | Common | Form 4 ↗ |
Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Adams Catherine Owen | Director | 2026-06-13 | D | 1,976 | $0 | $0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-13 | D | 1,976 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-13 | A | 1,976 | 0 | 0 | Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | A | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cecilia Jones | Chief Financial Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | A | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| James Burns | Chief Legal Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Krishnan Viswanadhan | Chief Strategy and Operations | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Cynthia Smith | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David Scadden | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Adams Catherine Owen | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Maykin Ho | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jacqualyn A. Fouse | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Kaye I. Foster-Cheek | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | D | 2,816 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jeffrey Capello | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 14,950 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,927 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Rahul Ballal | Director | 2026-06-18 | A | 2,816 | 0 | 0 | Common | Form 4 ↗ |
| Tsveta Milanova | Chief Commercial Officer | 2026-06-18 | D | 3,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Brian Goff | Director | 2026-06-18 | D | 39,000 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | A | 8,375 | 0 | 0 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 8,375 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-07-01 | D | 4,007 | 38 | 150,503 | Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-07-08 | D | 1,447 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Jay Backstrom | Director | 2026-07-08 | A | 1,447 | 0 | 0 | Common | Form 4 ↗ |
| Sarah Gheuens | Chief Medical Officer | 2026-08-04 | D | 30,000 | 30 | 914,400 | Common | Form 4 ↗ |
| Executive | Award | Grant date | Threshold | Target | Granted | Maximum | Grant-date fair value |
|---|---|---|---|---|---|---|---|
| Cecilia Jones | OPTION | 2025-03-01 | — | — | 43,500 | — | $802,008 |
| Brian Goff | OPTION | 2025-03-01 | — | — | 142,500 | — | 2,627,252 |
| James Burns | OPTION | 2025-03-01 | — | — | 43,500 | — | 802,008 |
| Sarah Gheuens | PSU | 2025-03-01 | — | 12,000 | — | 12,000 | 0 |
| Sarah Gheuens | OPTION | 2025-03-01 | — | — | 43,500 | — | 802,008 |
| James Burns | RSU | 2025-03-01 | — | — | 12,000 | — | 397,440 |
| Sarah Gheuens | RSU | 2025-03-01 | — | — | 12,000 | — | 397,440 |
| Krishnan Viswanadhan Pharm.D | OPTION | 2025-03-05 | — | — | 55,374 | — | 1,048,532 |
| Krishnan Viswanadhan | OPTION | 2025-03-05 | — | — | 55,374 | — | 1,048,532 |
| Krishnan Viswanadhan Pharm.D | RSU | 2025-03-05 | — | — | 24,300 | — | 824,985 |
| Cecilia Jones | PSU | 2025-03-01 | — | 12,000 | — | 12,000 | 0 |
| Cecilia Jones | RSU | 2025-03-01 | — | — | 12,000 | — | 397,440 |
| Krishnan Viswanadhan Pharm.D | PSU | 2025-03-05 | — | 28,200 | — | 28,200 | 0 |
| James Burns | PSU | 2025-03-01 | — | 12,000 | — | 12,000 | 0 |
| James Burns | RSU | 2025-03-01 | — | — | 11,759 | — | 389,458 |
| Cecilia Jones | RSU | 2025-03-01 | — | — | 15,910 | — | 526,939 |
| Brian Goff | PSU | 2025-03-01 | — | 78,000 | — | 78,000 | 0 |
| Brian Goff | RSU | 2025-03-01 | — | — | 39,000 | — | 1,291,680 |
| Named executive officer | Time-vested (RSU) | Performance-vested (PSU) | Options / SARs | % performance-vested |
|---|---|---|---|---|
| Cecilia Jones | $924,379 | $0 | $802,008 | 0.0% |
| Brian Goff | 1,291,680 | 0 | 2,627,252 | 0.0% |
| James Burns | 786,898 | 0 | 802,008 | 0.0% |
| Sarah Gheuens | 397,440 | 0 | 802,008 | 0.0% |
| Krishnan Viswanadhan Pharm.D | 824,985 | 0 | 1,048,532 | 0.0% |
| Krishnan Viswanadhan | 0 | 0 | 1,048,532 | 0.0% |
% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.
| Executive | Award | Shares unvested | Exercise price | Market value unvested |
|---|---|---|---|---|
| James Burns | Option | 33,750 | 32.27 | — |
| Sarah Gheuens | Option | 13,755 | 25.01 | — |
| Sarah Gheuens | RSU | 4,000 | — | 108,880 |
| James Burns | Option | 13,755 | 25.01 | — |
| James Burns | RSU | 23,759 | — | 646,720 |
| Sarah Gheuens | RSU | 12,000 | — | 326,640 |
| Sarah Gheuens | RSU | 24,300 | — | 661,446 |
| Cecilia Jones | Option | 22,203 | 27.88 | — |
| Cecilia Jones | RSU | 27,910 | — | 759,710 |
| Cecilia Jones | Option | 6,882 | 25.01 | — |
| James Burns | RSU | 11,333 | — | 308,484 |
| Brian Goff | RSU | 8,500 | — | 231,370 |
| Brian Goff | RSU | 39,000 | — | 1,061,580 |
| Sarah Gheuens | RSU | 8,375 | — | 227,968 |
| Brian Goff | RSU | 36,000 | — | 979,920 |
| Cecilia Jones | RSU | 11,333 | — | 308,484 |
| Sarah Gheuens | RSU | 11,333 | — | 308,484 |
| Brian Goff | Option | 29,535 | 25.01 | — |
| Cecilia Jones | Option | 43,500 | 33.12 | — |
| James Burns | RSU | 4,000 | — | 108,880 |
| Sarah Gheuens | Option | 33,750 | 32.27 | — |
| Cecilia Jones | RSU | 2,000 | — | 54,440 |
| Brian Goff | Option | 93,520 | 29.38 | — |
| Brian Goff | Option | 109,971 | 32.27 | — |
| Sarah Gheuens | Option | 2,565 | 32.2 | — |
| Brian Goff | Option | 142,500 | 33.12 | — |
| Cecilia Jones | Option | 33,750 | 32.27 | — |
| James Burns | Option | 2,565 | 32.2 | — |
| James Burns | Option | 43,500 | 33.12 | — |
| Sarah Gheuens | Option | 43,500 | 33.12 | — |
| Sarah Gheuens | Option | 55,374 | 33.95 | — |
The company rewards executives in a manner that reinforces a pay-for-performance philosophy and culture, ensuring that a substantial portion of executive compensation is 'at-risk' and variable to align executives' interests with those of stockholders. The program aims to attract and retain superior executives, motivate the achievement of performance goals that correlate to stockholder value, and reward sustainable value creation through strong company performance and progress toward the company's mission.
| CEO STI target (% of salary) | 70% |
|---|---|
| CEO LTI target (% of salary) | — |
| Independent consultant | Aon |
| Clawback policy | true |
| Anti-hedging | true |
| Anti-pledging | true |
| Meeting year | Meeting date | For | Against | Abstain | Support | Outcome |
|---|---|---|---|---|---|---|
| 2026 | 2026-06-18 | 43,396,045 | 1,086,059 | 1,606,976 | 97.56% | Passed |
| 2025 | 2025-06-18 | 46,843,926 | 3,024,905 | 16,430 | 93.93% | Passed |
| 2024 | 2024-06-20 | 47,985,871 | 3,120,093 | 13,404 | 93.89% | Passed |
| 2023 | 2023-06-13 | 46,289,192 | 4,630,627 | 9,604 | 90.91% | Passed |
| 2022 | 2022-06-21 | 45,023,409 | 4,523,606 | 9,007 | 90.87% | Passed |
| 2021 | 2021-05-20 | 58,442,174 | 6,173,957 | 7,427 | 90.45% | Passed |
Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.
| Meeting year | Meeting date | Approval — company's computation |
|---|---|---|
| 2026 | 2026-06-18 | 97.56%a |
| 2025 | 2025-06-18 | 93.93%b |
| 2024 | 2024-06-20 | 93.89%c |
a. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
b. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
c. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes will have no effect on the outcome of this proposal.”.
Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.
| Ratio (CEO : median employee) | 18 : 1 |
|---|---|
| CEO total compensation | $5,370,389 |
| Median employee compensation | $303,140 |
| Director | Cash fees | Stock awards | Option awards | Non-equity incentive | All other | Total |
|---|---|---|---|---|---|---|
| Jay BackstromIndependent · Science and Technology | $27,656 | $157,491 | $472,002 | $0 | $0 | $657,149 |
| Kaye FosterIndependent · Lead Independent Director · Compensation & People · Nominating and Corporate Governance (Chair) | 98,750 | 99,968 | 299,689 | 0 | 0 | 498,407 |
| Jacqualyn A. FouseIndependent · Science and Technology | 92,500 | 99,968 | 299,689 | 0 | 0 | 492,157 |
| Jeffrey CapelloIndependent · Audit (Chair) | 70,000 | 99,968 | 299,689 | 0 | 0 | 469,657 |
| David ScaddenIndependent · Nominating and Corporate Governance · Science and Technology (Chair) | 70,000 | 99,968 | 299,689 | 0 | 0 | 469,657 |
| Rahul BallalIndependent · Audit · Science and Technology | 67,500 | 99,968 | 299,689 | 0 | 0 | 467,157 |
| Cynthia SmithIndependent · Compensation & People (Chair) | 67,500 | 99,968 | 299,689 | 0 | 0 | 467,157 |
| Maykin HoIndependent · Audit · Nominating and Corporate Governance | 65,000 | 99,968 | 299,689 | 0 | 0 | 464,657 |
| Catherine Owen AdamsIndependent · Compensation & People | 58,750 | 99,968 | 299,689 | 0 | 0 | 458,407 |
| David P. SchenkeinIndependent · Departed during FY | 9,424 | 0 | 0 | 0 | 0 | 9,424 |
| Brian GoffEmployee director | 0 | 0 | 0 | — | 0 | 0 |
| Annual cash retainer | $50,000 |
|---|---|
| Annual equity retainer | $400,000 |
| Per board meeting fee | — |
| Committee chair fees (audit / comp / nom-gov) | 20,000 / 17,500 / 10,000 |
| Stock ownership guideline | $3 |
| Component | FY2025 |
|---|---|
| Cash retainers and fees | $627,080 |
| Equity awards (grant-date value) | $957,235 |
| All other compensation | $0 |
| Total cost of the board | $1,584,315 |
Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.
The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.
Of the companies AGIOS PHARMACEUTICALS, INC. names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.
Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including AGIOS PHARMACEUTICALS, INC..
Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.
| Rank | Company | FY | Chief executive | Salary | Stock awards | Option awards | Non-equity incentive | Total |
|---|---|---|---|---|---|---|---|---|
| 1 | Soleno Therapeutics, Inc. | 2024 | Anish Bhatnagar | $640,000 | $46,883,000 | $3,231,230 | $403,200 | $51,160,430 |
| 2 | TG Therapeutics, Inc. | 2025 | Michael Weiss | 875,000 | 23,550,000 | 0 | 1,146,250 | 25,571,250 |
| 3 | Rhythm Pharmaceuticals, Inc. | 2025 | David Meeker | 807,692 | 8,274,785 | 7,688,560 | 759,488 | 17,544,525 |
| 4 | SpringWorks Therapeutics, Inc. | 2024 | Saqib Islam | 760,000 | 7,899,760 | 6,689,100 | 798,000 | 16,153,317 |
| 5 | Blueprint Medicines Corporation | 2024 | Kathryn Haviland | 821,363 | 7,472,480 | 4,315,144 | 854,217 | 13,477,004 |
| 6 | BioCryst Pharmaceuticals, Inc. | 2025 | Jon Stonehouse | 728,466 | 0 | 11,132,458 | 1,052,633 | 12,951,082 |
| 7 | Crinetics Pharmaceuticals, Inc. | 2025 | R. Scott Struthers | 718,500 | 3,280,540 | 7,160,564 | 462,355 | 11,628,959 |
| 8 | Ultragenyx Pharmaceutical Inc. | 2025 | Emil Kakkis | 861,100 | 8,364,938 | 1,847,356 | 299,663 | 11,405,535 |
| 9 | Apellis Pharmaceuticals, Inc. | 2024 | Cedric Francois | 793,193 | 4,779,832 | 4,787,768 | 0 | 10,957,451 |
| 10 | Mirum Pharmaceuticals, Inc. | 2025 | Christopher Peetz | 755,000 | 3,683,904 | 4,931,320 | 1,057,000 | 10,441,224 |
| 11 | Axome Therapeutics, Inc. | 2025 | Herriot Tabuteau | 835,000 | 5,533,554 | 2,833,237 | 876,750 | 10,283,492 |
| 12 | Arcus Biosciences, Inc. | 2025 | Terry Rosen | 775,000 | 2,199,450 | 6,008,860 | 658,750 | 9,656,813 |
| 13 | Amicus Therapeutics, Inc. | 2024 | Bradley Campbell | 767,308 | 4,990,365 | 2,105,627 | 0 | 8,526,943 |
| 14 | Travere Therapeutics, Inc. | 2025 | Eric Dube | 854,250 | 3,314,520 | 3,309,384 | 964,125 | 8,457,151 |
| 15 | ACADIA Pharmaceuticals Inc. | 2025 | Catherine Owen Adams | 930,000 | 3,240,558 | 3,234,797 | 818,559 | 8,256,518 |
| 16 | Sage Therapeutics, Inc. | 2024 | Barry Greene | 830,712 | 3,164,364 | 2,669,263 | 431,970 | 7,112,589 |
| 17 | Syndax Pharmaceuticals, Inc. | 2025 | Michael Metzger | 754,300 | 2,021,965 | 3,454,360 | 848,588 | 7,089,213 |
| 18 | AGIOS PHARMACEUTICALS, INC. | 2025 | Brian Goff | 846,864 | 1,291,680 | 2,627,252 | 592,804 | 5,370,389 |
| 19 | Intellia Therapeutics, Inc. | 2025 | John Leonard | 708,000 | 2,443,920 | 1,356,320 | 0 | 5,063,899 |
Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.
| Company | Annual incentive payout | Long-term vehicle mix | PSU measures include TSR | Compensation consultant |
|---|---|---|---|---|
| AGIOS PHARMACEUTICALS, INC. | 100% | Option 40 · PSU 40 · RSU 20 | No | Aon |
| ACADIA Pharmaceuticals Inc. | 110% | Options 50 · PSU 25 · RSU 25 | Yes | Frederic W. Cook & Co., Inc. (FW Cook) |
| Amicus Therapeutics, Inc. | not disclosed | Option 33 · RSU 33 · PRSU 33 | Yes — TSR Goal | Pay Governance |
| Apellis Pharmaceuticals, Inc. | 90.74% | RSU 50 · PSU 50 | not disclosed | Pay Governance |
| Arcus Biosciences, Inc. | 100% | Options 67 · RSU 33 | not disclosed | Radford |
| Axome Therapeutics, Inc. | 150% | RSU 33 · Options 33 · PSU 33 | No | Frederic W. Cook & Co., Inc. |
| BioCryst Pharmaceuticals, Inc. | not disclosed | not disclosed | not disclosed | Aon |
| Blueprint Medicines Corporation | 130% | RSU 37 · Options 32 · PSU 31 | Yes — Relative Total Stockholder Return (rTSR) | Aon |
| Crinetics Pharmaceuticals, Inc. | not disclosed | Options 70 · RSU 30 | not disclosed | Pearl Meyer |
| Intellia Therapeutics, Inc. | 115% | Option 40 · RSU 40 · PSU 20 | Yes — TSR relative to the Nasdaq Biotechnology Index | Alpine |
| Mirum Pharmaceuticals, Inc. | 200% | Option 47.2 · PSU 17.6 · RSU 17.6 | No | Alpine Rewards |
| Rhythm Pharmaceuticals, Inc. | 120% | Options 50 · RSU 50 | No | Pay Governance |
| Sage Therapeutics, Inc. | 80% | not disclosed | Yes — TSR milestones / Relative TSR vs. Nasdaq Biotechnology Index | Alpine Rewards |
| Soleno Therapeutics, Inc. | not disclosed | not disclosed | not disclosed | Aon plc |
| SpringWorks Therapeutics, Inc. | 140% | not disclosed | Yes — Relative Total Shareholder Return (TSR) | Aon |
| Syndax Pharmaceuticals, Inc. | 150% | Options 34 · PSU 33 · RSU 33 | Yes — Company's three-year total shareholder return (TSR) as measured against the Nasdaq Biotechnology Index components TSRs | Aon |
| TG Therapeutics, Inc. | 131% | RSU 100 | No | Compensia, Inc. |
| Travere Therapeutics, Inc. | 150% | not disclosed | No | Aon |
| Ultragenyx Pharmaceutical Inc. | 44% | PSU 60 · RSU 20 · Options 20 | Yes — Relative TSR | Aon's Human Capital Solutions Practice |
Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.
Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.
Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.
| # | Supports | Document | Filed | Accession | Location in document |
|---|---|---|---|---|---|
| 1 | Section 01, Brian Goff | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation”. As printed: 5,370,389. Filing ↗machine: r2 · c31 · span 613185–613194 |
| 2 | Section 01, Krishnan Viswanadhan | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation”. As printed: 2,805,026. Filing ↗machine: r14 · c30 · span 642579–642588 |
| 3 | Section 01, Cecilia Jones | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation”. As printed: 2,518,222. Filing ↗machine: r5 · c31 · span 620543–620552 |
| 4 | Section 01, James Burns | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation”. As printed: 2,369,416. Filing ↗machine: r8 · c31 · span 627870–627879 |
| 5 | Section 01, Sarah Gheuens | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation”. As printed: 2,086,680. Filing ↗machine: r11 · c31 · span 635233–635242 |
| 6 | Section 03, Cecilia Jones OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 686456–686463 |
| 7 | Section 03, Brian Goff OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 672554–672563 |
| 8 | Section 03, James Burns OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 700591–700598 |
| 9 | Section 03, Sarah Gheuens PSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 704705–704711 |
| 10 | Section 03, Sarah Gheuens OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 712267–712274 |
| 11 | Section 03, James Burns RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗ |
| 12 | Section 03, Sarah Gheuens RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗ |
| 13 | Section 03, Krishnan Viswanadhan Pharm.D OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 724046–724055 |
| 14 | Section 03, Krishnan Viswanadhan OPTION | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t222 · r24 · c47 · span 724046–724055 |
| 15 | Section 03, Krishnan Viswanadhan Pharm.D RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 719719–719726 |
| 16 | Section 03, Cecilia Jones PSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 676545–676551 |
| 17 | Section 03, Cecilia Jones RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗ |
| 18 | Section 03, Krishnan Viswanadhan Pharm.D PSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 716434–716440 |
| 19 | Section 03, James Burns PSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 690605–690611 |
| 20 | Section 03, James Burns RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 696264–696271 |
| 21 | Section 03, Cecilia Jones RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 682154–682161 |
| 22 | Section 03, Brian Goff PSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 665162–665168 |
| 23 | Section 03, Brian Goff RSU | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Executive Compensation” · grants of plan-based awards table. Filing ↗machine: span 668224–668233 |
| 24 | Section 07, pay ratio | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “CEO Pay Ratio”. As printed: 18 : 1. Filing ↗ |
| 25 | Section 08, Jay Backstrom | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 657,149. Filing ↗machine: span 335199–335206 |
| 26 | Section 08, Kaye Foster | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 498,407. Filing ↗machine: span 339481–339488 |
| 27 | Section 08, Jacqualyn A. Fouse | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 492,157. Filing ↗machine: span 340932–340939 |
| 28 | Section 08, Jeffrey Capello | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 469,657. Filing ↗machine: span 338066–338073 |
| 29 | Section 08, David Scadden | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 469,657. Filing ↗machine: span 345224–345231 |
| 30 | Section 08, Rahul Ballal | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 467,157. Filing ↗machine: span 336622–336629 |
| 31 | Section 08, Cynthia Smith | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 467,157. Filing ↗machine: span 348171–348178 |
| 32 | Section 08, Maykin Ho | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 464,657. Filing ↗machine: span 342352–342359 |
| 33 | Section 08, Catherine Owen Adams | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 458,407. Filing ↗machine: span 343801–343808 |
| 34 | Section 08, David P. Schenkein | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 9,424. Filing ↗machine: span 346756–346761 |
| 35 | Section 08, Brian Goff | DEF 14A | 2026-04-24 | 0001193125-26-177086 | Section “Director Compensation”. As printed: 0. Filing ↗ |
| 36 | Section 02, Adams Catherine Owen 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000077 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 37 | Section 02, Jeffrey Capello 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000075 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 38 | Section 02, Adams Catherine Owen 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000077 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 39 | Section 02, Jeffrey Capello 2026-06-13 | Form 4 | 2026-06-16 | 0001439222-26-000075 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 40 | Section 02, Cecilia Jones 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000083 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 41 | Section 02, Krishnan Viswanadhan 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000091 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 42 | Section 02, Brian Goff 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000089 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 43 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 44 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 45 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 46 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 47 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 48 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 49 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 50 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 51 | Section 02, Tsveta Milanova 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000081 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 52 | Section 02, Jay Backstrom 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000079 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 53 | Section 02, Sarah Gheuens 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000085 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 54 | Section 02, Sarah Gheuens 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000085 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 55 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 56 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 57 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 58 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 59 | Section 02, Jay Backstrom 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000079 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 60 | Section 02, Cecilia Jones 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000083 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 61 | Section 02, James Burns 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000087 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 62 | Section 02, James Burns 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000087 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 63 | Section 02, Krishnan Viswanadhan 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000091 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 64 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 65 | Section 02, Cynthia Smith 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000093 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 66 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 67 | Section 02, David Scadden 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000095 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 68 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 69 | Section 02, Adams Catherine Owen 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000097 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 70 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 71 | Section 02, Maykin Ho 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000099 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 72 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 73 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 74 | Section 02, Jacqualyn A. Fouse 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000101 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 75 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 76 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 77 | Section 02, Kaye I. Foster-Cheek 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000103 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 78 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 79 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 80 | Section 02, Jeffrey Capello 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000105 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 81 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 82 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 83 | Section 02, Rahul Ballal 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000107 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 84 | Section 02, Tsveta Milanova 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000081 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 85 | Section 02, Brian Goff 2026-06-18 | Form 4 | 2026-06-23 | 0001439222-26-000089 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 86 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 87 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 88 | Section 02, Sarah Gheuens 2026-07-01 | Form 4 | 2026-07-02 | 0001439222-26-000110 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 89 | Section 02, Jay Backstrom 2026-07-08 | Form 4 | 2026-07-10 | 0001439222-26-000112 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 90 | Section 02, Jay Backstrom 2026-07-08 | Form 4 | 2026-07-10 | 0001439222-26-000112 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 91 | Section 02, Sarah Gheuens 2026-08-04 | Form 4 | 2026-08-06 | 0001439222-26-000120 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 92 | Section 06, 2026 vote | Form 8-K | 2026-06-18 | 0001193125-26-275879 | Item 5.07 · say-on-pay result. As reported: 97.56% (votes for as printed: 43,396,045). Filing ↗ |
| 93 | Section 06, 2025 vote | Form 8-K | 2025-06-18 | 0001193125-25-142745 | Item 5.07 · say-on-pay result. As reported: 93.93% (votes for as printed: 46,843,926). Filing ↗ |
| 94 | Section 06, 2024 vote | Form 8-K | 2024-06-20 | 0001193125-24-164555 | Item 5.07 · say-on-pay result. As reported: 93.89% (votes for as printed: 47,985,871). Filing ↗ |
| 95 | Section 01 trend, Δ column (computed) | Computed | — | — | Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1) |
| 96 | Section 03b vehicle mix (computed) | Computed | — | — | RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio |
| 97 | Section 09b board cost (computed) | Computed | — | — | Cash 627,080 + equity 957,235 + all other 0 = 1,584,315, summed across the director compensation table rows.machine: formula: Σ = 1,584,315 |
| 98 | Soleno Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-22 | 0001193125-25-089274 | CEO total compensation as printed in Soleno Therapeutics, Inc.'s own proxy. As printed: 51,160,430. Filing ↗machine: r2 · c27 · span 288252–288262 |
| 99 | TG Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-30 | 0001437749-26-014233 | CEO total compensation as printed in TG Therapeutics, Inc.'s own proxy. As printed: 25,571,250. Filing ↗machine: r4 · c24 · span 404551–404561 |
| 100 | Rhythm Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-29 | 0001628280-26-028375 | CEO total compensation as printed in Rhythm Pharmaceuticals, Inc.'s own proxy. As printed: 17,544,525. Filing ↗machine: r2 · c42 · span 513064–513074 |
| 101 | SpringWorks Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-04 | 0001104659-25-032187 | CEO total compensation as printed in SpringWorks Therapeutics, Inc.'s own proxy. As printed: 16,153,317. Filing ↗machine: r1 · c47 · span 623184–623194 |
| 102 | Blueprint Medicines Corporation, Section 10b CEO total | DEF 14A | 2025-04-24 | 0001558370-25-005415 | CEO total compensation as printed in Blueprint Medicines Corporation's own proxy. As printed: 13,477,004. Filing ↗machine: span 1101152–1101162 |
| 103 | BioCryst Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-23 | 0001628280-26-026822 | CEO total compensation as printed in BioCryst Pharmaceuticals, Inc.'s own proxy. As printed: 12,951,082. Filing ↗machine: span 512256–512266 |
| 104 | Crinetics Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-29 | 0001658247-26-000030 | CEO total compensation as printed in Crinetics Pharmaceuticals, Inc.'s own proxy. As printed: 11,628,959. Filing ↗machine: r2 · c48 · span 589450–589460 |
| 105 | Ultragenyx Pharmaceutical Inc., Section 10b CEO total | DEF 14A | 2026-03-27 | 0001308179-26-000174 | CEO total compensation as printed in Ultragenyx Pharmaceutical Inc.'s own proxy. As printed: 11,405,535. Filing ↗machine: span 668997–669007 |
| 106 | Apellis Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2025-04-23 | 0000950170-25-056966 | CEO total compensation as printed in Apellis Pharmaceuticals, Inc.'s own proxy. As printed: 10,957,451. Filing ↗machine: r2 · c25 · span 951555–951565 |
| 107 | Mirum Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-23 | 0001759425-26-000027 | CEO total compensation as printed in Mirum Pharmaceuticals, Inc.'s own proxy. As printed: 10,441,224. Filing ↗machine: r2 · c21 · span 580200–580210 |
| 108 | Axome Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-24 | 0001193125-26-177610 | CEO total compensation as printed in Axome Therapeutics, Inc.'s own proxy. As printed: 10,283,492. Filing ↗machine: t51 · r2 · c27 · span 900236–900246 |
| 109 | Arcus Biosciences, Inc., Section 10b CEO total | DEF 14A | 2026-04-21 | 0001724521-26-000025 | CEO total compensation as printed in Arcus Biosciences, Inc.'s own proxy. As printed: 9,656,813. Filing ↗machine: r2 · c48 · span 403740–403749 |
| 110 | Amicus Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-24 | 0001140361-25-015479 | CEO total compensation as printed in Amicus Therapeutics, Inc.'s own proxy. As printed: 8,526,943. Filing ↗machine: r2 · c25 · span 736126–736136 |
| 111 | Travere Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-06 | 0001438533-26-000027 | CEO total compensation as printed in Travere Therapeutics, Inc.'s own proxy. As printed: 8,457,151. Filing ↗machine: span 558514–558523 |
| 112 | ACADIA Pharmaceuticals Inc., Section 10b CEO total | DEF 14A | 2026-04-24 | 0001193125-26-174163 | CEO total compensation as printed in ACADIA Pharmaceuticals Inc.'s own proxy. As printed: 8,256,518. Filing ↗ |
| 113 | Sage Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2025-04-24 | 0000950170-25-058060 | CEO total compensation as printed in Sage Therapeutics, Inc.'s own proxy. As printed: 7,112,589. Filing ↗machine: r4 · c28 · span 1143784–1143793 |
| 114 | Syndax Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-30 | 0001193125-26-197859 | CEO total compensation as printed in Syndax Pharmaceuticals, Inc.'s own proxy. As printed: 7,089,213. Filing ↗machine: span 936322–936331 |
| 115 | AGIOS PHARMACEUTICALS, INC. (subject), Section 10b CEO total | DEF 14A | 2026-04-24 | 0001193125-26-177086 | CEO total compensation as printed in AGIOS PHARMACEUTICALS, INC.'s own proxy. As printed: 5,370,389. Filing ↗machine: r2 · c31 · span 613185–613194 |
| 116 | Intellia Therapeutics, Inc., Section 10b CEO total | DEF 14A | 2026-04-30 | 0001193125-26-197283 | CEO total compensation as printed in Intellia Therapeutics, Inc.'s own proxy. As printed: 5,063,899. Filing ↗machine: r2 · c25 · span 749290–749299 |
| 117 | Section 10a, Syndax Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001193125-26-197859 | Syndax Pharmaceuticals, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 118 | Section 10a, ACADIA Pharmaceuticals Inc. reciprocity | DEF 14A | — | 0001193125-26-174163 | ACADIA Pharmaceuticals Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 119 | Section 10a, Amicus Therapeutics, Inc. reciprocity | DEF 14A | — | 0001140361-25-015479 | Amicus Therapeutics, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 120 | Section 10a, Sage Therapeutics, Inc. reciprocity | DEF 14A | — | 0000950170-25-058060 | Sage Therapeutics, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 121 | Section 10a, Axome Therapeutics, Inc. reciprocity | DEF 14A | — | 0001193125-26-177610 | Axome Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 122 | Section 10a, Soleno Therapeutics, Inc. reciprocity | DEF 14A | — | 0001193125-25-089274 | Soleno Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 123 | Section 10a, TG Therapeutics, Inc. reciprocity | DEF 14A | — | 0001437749-26-014233 | TG Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 124 | Section 10a, Travere Therapeutics, Inc. reciprocity | DEF 14A | — | 0001438533-26-000027 | Travere Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 125 | Section 10a, Intellia Therapeutics, Inc. reciprocity | DEF 14A | — | 0001193125-26-197283 | Intellia Therapeutics, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 126 | Section 10a, BioCryst Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001628280-26-026822 | BioCryst Pharmaceuticals, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 127 | Section 10a, Crinetics Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001658247-26-000030 | Crinetics Pharmaceuticals, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 128 | Section 10a, SpringWorks Therapeutics, Inc. reciprocity | DEF 14A | — | 0001104659-25-032187 | SpringWorks Therapeutics, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 129 | Section 10a, Ultragenyx Pharmaceutical Inc. reciprocity | DEF 14A | — | 0001308179-26-000174 | Ultragenyx Pharmaceutical Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 130 | Section 10a, Rhythm Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001628280-26-028375 | Rhythm Pharmaceuticals, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 131 | Section 10a, Mirum Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001759425-26-000027 | Mirum Pharmaceuticals, Inc. names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 132 | Section 10a, Apellis Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0000950170-25-056966 | Apellis Pharmaceuticals, Inc.'s most recent proxy was read; its disclosed peer group does not include AGIOS PHARMACEUTICALS, INC.. Filing ↗ |
| 133 | Section 10a, Blueprint Medicines Corporation reciprocity | DEF 14A | — | 0001558370-25-005415 | Blueprint Medicines Corporation names AGIOS PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
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