Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-08-20

ARROWHEAD PHARMACEUTICALS, INC. (ARWR)

CEO Christopher Anzalone was paid $9,029,861 in fiscal year 2025, ↓ down 27.3% from fiscal year 2024, the 47th percentile of its disclosed peer group (SEC filing 0000879407-26-000019 ↗): executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$9,029,861 ↓
Christopher Anzalone total, FY2025
47th
CEO pay percentile vs peers
55:1
CEO-to-median pay ratio
40.97%
Say-on-pay support, latest vote

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Sample answer — “What is the CEO’s total compensation?”
- Christopher Anzalone (President and Chief Executive Officer), FY2025 total compensation $9,029,861 (base salary $981,046) [exec_comp, SEC accession 0000879407-26-000019, filed 2026-01-27]

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ARWR's next annual pay disclosure, estimated January 25, 2027.est. Filing ↗

Page 2 of 34 of the ARROWHEAD PHARMACEUTICALS, INC. Executive Compensation Report, as it is delivered: Executive Summary.

That is page 2 of 34 of the full Executive Compensation Report, shown as it is delivered. The rest:

  1. Summary Compensation Table
  2. Equity transactions since the proxy statement
  3. Grants of plan-based awards
  4. Outstanding equity awards at fiscal year-end
  5. Incentive-plan design (CD&A)
  6. Say-on-pay
  7. CEO pay ratio
  8. Director compensation
  9. Board fee structure and ownership guideline
  10. Disclosed peer group
  11. Source register

Every figure above cites the filing it came from (accession 0000879407-26-000019, filed 2026-08-20) — see the source register, §11.

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Christopher Anzalone$981,046$0$6,810,292$0$1,236,000$0$2,523$9,029,861
President and Chief Executive Officer
Patrick O'Brien653,94001,979,0000365,638031,6173,030,195
Chief Operating Officer
James Hamilton617,51201,979,0000354,627015,0742,966,213
Chief Medical Officer
Kenneth Myszkowski496,78301,979,0000155,776028,6012,660,161
Former Chief Financial Officer
Tracie Oliver43,19300000043,193
Former Chief Commercial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY2024→2025
Christopher Anzalone$9,029,861$12,423,473$9,918,093↓ −3,393,612
Patrick O'Brien3,030,1953,933,5703,310,337↓ −903,375
James Hamilton2,966,2133,487,4443,046,943↓ −521,231
Kenneth Myszkowski2,660,1613,512,3763,119,143↓ −852,215
Tracie Oliver43,1933,076,780873,822↓ −3,033,587

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

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Data as of August 20, 2026 · Source: 0000879407-26-000019 · Velarion Executive Compensation Database, deposited on Zenodo (doi:10.5281/zenodo.22283855).

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Companies that benchmark against ARWR
24 companies name ARWR as a compensation peer

Each company listed discloses ARWR in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named ARWR in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

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01b

Executives — the named officers

One page per officer: the same table above, read for one person at a time — his own figure and every fiscal year the register holds.

ExecutiveRoleFY2025 total
Christopher AnzaloneCEO$9,029,861
James HamiltonChief Medical Officer$2,966,213
Kenneth MyszkowskiChief Financial Officer$2,660,161
Patrick O'BrienCOO$3,030,195
Tracie OliverChief Commercial Officer$43,193
01c

Board of directors

One page per director: the seat, the committees and the fee table, read for one person at a time.

DirectorRoleFY2025 total
Adeoye OlukotunIndependent Director$420,684
Douglas IngramIndependent Director$846,350
Douglass GivenFormer director (through FY2025)$23,750
Hongbo LuIndependent Director$420,684
Mauro FerrariIndependent Director$420,684
Michael S. PerryIndependent Director$428,184
Victoria VakienerIndependent Director$424,434
William WaddillIndependent Director$438,184
02

Equity transactions since the proxy statement was filed

Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.

InsiderRoleTransaction dateCodeSharesPriceValueSecuritySource
James HamiltonChief Medical Officer2026-03-05D10,000$64$641,900CommonForm 4 ↗
Daniel Joseph ApelChief Financial Officer2026-04-22D8,73072627,862CommonForm 4 ↗
Daniel Joseph ApelChief Financial Officer2026-04-22D3,20870224,913CommonForm 4 ↗
Daniel Joseph ApelChief Financial Officer2026-04-22D1,1577081,511CommonForm 4 ↗
James HamiltonChief Medical Officer2026-04-23D10,00075750,000CommonForm 4 ↗
Hongbo LuDirector2026-05-12D2,97077228,334CommonForm 4 ↗
Matthew Gregory CohenDirector2026-06-15A11,88200CommonForm 4 ↗
Adeoye OlukotunDirector2026-08-18D2,00087173,920CommonForm 4 ↗
Michael S. PerryDirector2026-08-18D11,600871,012,680CommonForm 4 ↗

Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.

03

Grants of plan-based awards — fiscal year 2025

ExecutiveAwardGrant dateThresholdTargetGrantedMaximumGrant-date fair value
James HamiltonRSU2025-01-04——100,000—$1,979,000
Christopher AnzalonePSU2024-12-18—225,000——4,581,000
Christopher AnzaloneRSU2024-12-18—100,000—2,036,0002,036,000
Kenneth MyszkowskiRSU2025-01-04——100,000—1,979,000
Patrick O'BrienRSU2025-01-04——100,000—1,979,000
Christopher AnzaloneRSU2025-02-07—9,550——193,292
Daniel ApelRSU2025-04-15——100,000—1,287,000
Patrick O BrienRSU2025-01-04——100,000—1,979,000
03b

Vehicle mix — grant-date fair value by award type

Named executive officerTime-vested (RSU)Performance-vested (PSU)Options / SARs% performance-vested
James Hamilton$1,979,000$0$00.0%
Christopher Anzalone2,229,2924,581,000067.3%
Kenneth Myszkowski1,979,000000.0%
Patrick O'Brien1,979,000000.0%
Daniel Apel1,287,000000.0%
Patrick O Brien1,979,000000.0%

% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
James HamiltonRSU100,000—$3,449,000
Kenneth MyszkowskiRSU100,000—3,449,000
James HamiltonRSU30,000—1,034,700
Patrick O'BrienRSU100,000—3,449,000
Christopher AnzaloneRSU800,000—27,592,000
James HamiltonRSU13,750—474,238
James HamiltonRSU56,250—1,940,063
Kenneth MyszkowskiRSU56,250—1,940,063
Christopher AnzaloneRSU700,000—24,143,000
Christopher AnzalonePSU93,610—3,228,609
Christopher AnzaloneRSU46,805—1,614,304
Christopher AnzaloneRSU24,881—858,146
Kenneth MyszkowskiRSU15,000—517,350
Christopher AnzaloneOption51,7266.15—
Christopher AnzalonePSU225,000—7,760,250
Christopher AnzaloneRSU100,000—3,449,000
Christopher AnzalonePSU49,761—1,716,257
Patrick O'BrienRSU63,750—2,198,738
Kenneth MyszkowskiRSU30,000—1,034,700
Patrick O'BrienRSU32,500—1,120,925
Patrick O'BrienRSU15,000—517,350
05

Incentive-plan design — the Compensation Discussion & Analysis

Our executive compensation philosophy reflects our two fundamental objectives: to attract, motivate and retain a highly skilled team of executives; and to align our executive officers interests with those of our stockholders by rewarding short-term and long-term performance and aligning compensation to increases in stockholder value.

CEO STI target (% of salary)100%
CEO LTI target (% of salary)—
Independent consultantCompensia
Clawback policyTrue
Anti-hedgingTrue
Anti-pledgingFalse
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-03-1941,625,74059,963,903256,34140.97%Failed
20252025-03-1275,327,0727,389,926153,17690.9%Passed
20242024-03-1482,576,0474,950,419143,38594.34%Passed
20232023-03-1662,683,7187,119,440280,60789.44%Passed
20222022-03-1714,213,20254,813,812553,20820.43%Failed
20212021-03-1827,526,87433,678,4541,251,56444.07%Failed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20262026-03-1940.97%a
20252025-03-1290.9%b
20242024-03-1494.34%c

a. Approved under the standard stated in the filing — “Because directors are elected by a majority of votes cast, abstentions from voting and broker non-votes, if any, will have no effect on the outcome of this Proposal.”.

b. Approved under the standard stated in the filing — “2, 3 and 4 must be approved by the affirmative vote of a majority of the shares of Common Stock entitled to vote thereon and present in person or by proxy at the Annual Meeting (the " Required Vote "), abstentions will have the same effect as a vote "AGAINST" the proposal, whereas broker non-votes, if any, will have no effect on its outcome.”.

c. Approved under the standard stated in the filing — “Because directors are elected by a majority of votes cast in an uncontested election, abstentions from voting and broker non-votes, if any, will have no effect on its outcome.”.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

07

CEO pay ratio

Ratio (CEO : median employee)55 : 1
CEO total compensation$9,029,861
Median employee compensation$163,062
08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Douglas IngramIndependent · Not standing for re-election$60,000$786,350$0$0$0$846,350
William WaddillIndependent · Audit (Chair) · Compensation · Nomination97,500340,684000438,184
Michael S. PerryIndependent · Compensation (Chair) · Audit · Nomination · Science & Technology Committee87,500340,684000428,184
Victoria VakienerIndependent · Audit · Nomination (Chair)83,750340,684000424,434
Mauro FerrariIndependent · Audit · Nomination · Science & Technology Committee (Co-Chair)80,000340,684000420,684
Adeoye OlukotunIndependent · Nomination · Science & Technology Committee (Co-Chair)80,000340,684000420,684
Hongbo LuIndependent · Compensation · Nomination Committee · Science & Technology Committee80,000340,684000420,684
Douglass GivenNot independent · Departed during FY23,750000023,750
Christopher AnzaloneEmployee director · Board Chair000—00
09

Board fee structure and ownership guideline

Annual cash retainer$80,000
Annual equity retainer$340,684
Per board meeting fee—
Committee chair fees (audit / comp / nom-gov)5,000 / 10,000 / 5,000
Stock ownership guidelineguidelines mandating ownership of Arrowhead stock in amounts equal to, for our CEO, six times annual base salary and, for our CFO and COO, two times annual base salary.
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$592,500
Equity awards (grant-date value)$2,830,454
All other compensation$0
Total cost of the board$3,422,954

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10

Disclosed peer group — fiscal year 2025

The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.

10a

Peer reciprocity

Of the companies ARROWHEAD PHARMACEUTICALS, INC. names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.

Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including ARROWHEAD PHARMACEUTICALS, INC..

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Halozyme Therapeutics2025Helen Torley$1,000,000$19,350,145$1,650,014$1,147,500$23,166,223
2Madrigal Pharmaceuticals2025Bill Sibold918,53112,297,8504,537,1461,438,81419,206,341
3BridgeBio Pharma2025Neil Kumar1,044,00010,606,2751,874,992014,944,585
4Blueprint Medicines2024Kathryn Haviland821,3637,472,4804,315,144854,21713,477,004
5Ionis Pharmaceuticals2025Brett Monia1,051,7768,444,8381,438,105013,350,777
6BioCryst Pharmaceuticals2025Jon Stonehouse728,466011,132,4581,052,63312,951,082
7Ultragenyx Pharmaceuticals2025Emil Kakkis861,1008,364,9381,847,356299,66311,405,535
8Apellis Pharmaceuticals2024Cedric Francois793,1934,779,8324,787,768010,957,451
9Arcus Biosciences2025Terry Rosen775,0002,199,4506,008,860658,7509,656,813
10IDEAYA Biosciences2025Yujiro Hata700,00008,418,840378,0009,512,640
11ARROWHEAD PHARMACEUTICALS, INC.2025Christopher Anzalone981,0466,810,29201,236,0009,029,861
12Amicus Therapeutics2024Bradley Campbell767,3084,990,3652,105,62708,526,943
13ACADIA Pharmaceuticals, Inc.2025Catherine Owen Adams930,0003,240,5583,234,797818,5598,256,518
14Vir Biotechnology2025Marianne De Backer950,0002,296,8003,507,3601,002,7507,834,045
15CRISPR Therapeutics AG2025Samarth Kulkarni768,6223,474,9002,768,862659,0937,678,477
16Day One Biopharmaceuticals2024Jeremy Bender680,0002,700,2802,664,697501,8006,560,577
17AnaptysBio2025Daniel Faga706,0111,592,0013,345,653465,9686,133,943
18Intellia Therapeutics2025John Leonard708,0002,443,9201,356,32005,063,899
19Denali Therapeutics2025Ryan Watts718,0001,151,8672,180,00304,751,515
20Ironwood Pharmaceuticals2025Thomas McCourt867,568411,6960650,6761,948,390

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10c

Incentive design against the same peers

CompanyAnnual incentive payoutLong-term vehicle mixPSU measures include TSRCompensation consultant
ARROWHEAD PHARMACEUTICALS, INC.125%PSU 70 · RSU 30not disclosedCompensia
ACADIA Pharmaceuticals, Inc.110%Options 50 · PSU 25 · RSU 25YesFrederic W. Cook & Co., Inc. (FW Cook)
Amicus Therapeuticsnot disclosedOption 33 · RSU 33 · PRSU 33Yes — TSR GoalPay Governance
AnaptysBio110%not disclosedNoAlpine Rewards
Apellis Pharmaceuticals90.74%RSU 50 · PSU 50not disclosedPay Governance
Arcus Biosciences100%Options 67 · RSU 33not disclosedRadford
BioCryst Pharmaceuticalsnot disclosednot disclosednot disclosedAon
Blueprint Medicines130%RSU 37 · Options 32 · PSU 31Yes — Relative Total Stockholder Return (rTSR)Aon
BridgeBio Pharma135%RSU 50 · PSU 35 · Options 15NoAon Talent Solutions
CRISPR Therapeutics AGnot disclosednot disclosednot disclosedAlpine Rewards, LLC
Day One Biopharmaceuticals123%%Stock Options 50 · RSUs 50not disclosedCompensia Inc.
Denali Therapeutics145%not disclosednot disclosedAlpine Rewards
Halozyme Therapeutics127.5%PSU 50 · RSU 35 · Option 15NoF.W. Cook & Co., Inc.
IDEAYA Biosciences90%Options 100not disclosedAon (Aon plc, Talent Solutions practice)
Intellia Therapeutics115%Option 40 · RSU 40 · PSU 20Yes — TSR relative to the Nasdaq Biotechnology IndexAlpine
Ionis Pharmaceuticalsnot disclosedPRSU 40 · Option 30 · RSU 30Yes — Relative TSRAon
Ironwood Pharmaceuticals100%RSU 50 · PSU 50not disclosedAlpine Rewards LLC
Madrigal Pharmaceuticals195%PSU 33 · RSU 33 · Options 33Yes — Relative TSR vs Nasdaq Biotechnology IndexCompensia
Ultragenyx Pharmaceuticals44%PSU 60 · RSU 20 · Options 20Yes — Relative TSRAon's Human Capital Solutions Practice
Vir Biotechnology125%Options 67 · RSU 33not disclosedSemler Brossy

Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.

10d

Frequently asked questions

Who was the highest-paid executive at ARROWHEAD PHARMACEUTICALS, INC. in fiscal 2025?
As disclosed, Christopher Anzalone (President and Chief Executive Officer) was the highest-paid executive at ARROWHEAD PHARMACEUTICALS, INC. in fiscal 2025, with total compensation of $9,029,861.
How does ARROWHEAD PHARMACEUTICALS, INC.'s chief executive pay compare to its disclosed peer group?
As disclosed, Christopher Anzalone's total compensation ranked at the 47th percentile of ARROWHEAD PHARMACEUTICALS, INC.'s disclosed peer group.
What is ARROWHEAD PHARMACEUTICALS, INC.'s CEO-to-median employee pay ratio?
As disclosed, ARROWHEAD PHARMACEUTICALS, INC.'s CEO-to-median employee pay ratio was 55:1.
How did shareholders vote on ARROWHEAD PHARMACEUTICALS, INC.'s executive compensation?
As disclosed, 40.97% of shareholders supported ARROWHEAD PHARMACEUTICALS, INC.'s executive compensation in the latest say-on-pay vote.
How much does ARROWHEAD PHARMACEUTICALS, INC. spend in total on board compensation for fiscal 2025?
As disclosed, ARROWHEAD PHARMACEUTICALS, INC. reported total board compensation of $3,422,954 for fiscal 2025.

Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Christopher AnzaloneDEF 14A2026-01-270000879407-26-000019Section “Fiscal 2025 Summary Compensation Table”. As printed: 9,029,861. Filing ↗machine: span 692475–692484
2Section 01, Patrick O'BrienDEF 14A2026-01-270000879407-26-000019Section “Compensation Tables” · page 47. As printed: 3,030,195. Filing ↗machine: span 621005–621012
3Section 01, James HamiltonDEF 14A2026-01-270000879407-26-000019Section “Fiscal 2025 Summary Compensation Table”. As printed: 2,966,213. Filing ↗machine: r10 · c42 · span 711218–711227
4Section 01, Kenneth MyszkowskiDEF 14A2026-01-270000879407-26-000019Section “Fiscal 2025 Summary Compensation Table”. As printed: 2,660,161. Filing ↗machine: r13 · c42 · span 718323–718332
5Section 01, Tracie OliverDEF 14A2026-01-270000879407-26-000019Section “Fiscal 2025 Summary Compensation Table”. As printed: 43,193. Filing ↗machine: r16 · c42 · span 723930–723936
6Section 03, James Hamilton RSUDEF 14A2026-01-270000879407-26-000019Section “EACH OF THE NOMINEES FOR DIRECTOR IN PROPOSAL ONE.” · grants of plan-based awards table. Filing ↗machine: t91 · r10 · c7 · span 710275–710284
7Section 03, Christopher Anzalone PSUDEF 14A2026-01-270000879407-26-000019Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t98 · r8 · c13 · span 806958–806965
8Section 03, Christopher Anzalone RSUDEF 14A2026-01-270000879407-26-000019Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t98 · r8 · c9 · span 806370–806377
9Section 03, Kenneth Myszkowski RSUDEF 14A2026-01-270000879407-26-000019Section “EACH OF THE NOMINEES FOR DIRECTOR IN PROPOSAL ONE.” · grants of plan-based awards table. Filing ↗machine: t91 · r13 · c7 · span 717380–717389
10Section 03, Patrick O'Brien RSUDEF 14A2026-01-270000879407-26-000019Section “Executive Compensation” · grants of plan-based awards table. Filing ↗
11Section 03, Christopher Anzalone RSUDEF 14A2026-01-270000879407-26-000019Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗
12Section 03, Daniel Apel RSUDEF 14A2026-01-270000879407-26-000019Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t91 · r5 · c7 · span 699267–699276
13Section 03, Patrick O Brien RSUDEF 14A2026-01-270000879407-26-000019Section “EACH OF THE NOMINEES FOR DIRECTOR IN PROPOSAL ONE.” · grants of plan-based awards table. Filing ↗machine: t91 · r7 · c7 · span 702962–702971
14Section 07, pay ratioDEF 14A2026-01-270000879407-26-000019Section “CEO Pay Ratio”. As printed: 55 : 1. Filing ↗
15Section 08, Douglas IngramDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 846,350. Filing ↗machine: t42 · r7 · c5 · span 287118–287319
16Section 08, William WaddillDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 438,184. Filing ↗machine: t42 · r5 · c5 · span 285037–285158
17Section 08, Michael S. PerryDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 428,184. Filing ↗machine: t42 · r3 · c5 · span 282711–282832
18Section 08, Victoria VakienerDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 424,434. Filing ↗machine: t42 · r9 · c5 · span 289556–289677
19Section 08, Mauro FerrariDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 420,684. Filing ↗machine: t42 · r4 · c5 · span 283948–284069
20Section 08, Adeoye OlukotunDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 420,684. Filing ↗machine: t42 · r8 · c5 · span 288168–288394
21Section 08, Hongbo LuDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 420,684. Filing ↗machine: t42 · r6 · c5 · span 286268–286389
22Section 08, Douglass GivenDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 23,750. Filing ↗machine: t42 · r2 · c1 · span 280752–280872
23Section 08, Christopher AnzaloneDEF 14A2026-01-270000879407-26-000019Section “Director Compensation”. As printed: 0. Filing ↗
24Section 02, James Hamilton 2026-03-05Form 42026-03-090001830755-26-000006Insider equity transaction reported since the proxy statement. Filing ↗
25Section 02, Daniel Joseph Apel 2026-04-22Form 42026-04-240000879407-26-000039Insider equity transaction reported since the proxy statement. Filing ↗
26Section 02, Daniel Joseph Apel 2026-04-22Form 42026-04-240000879407-26-000039Insider equity transaction reported since the proxy statement. Filing ↗
27Section 02, Daniel Joseph Apel 2026-04-22Form 42026-04-240000879407-26-000039Insider equity transaction reported since the proxy statement. Filing ↗
28Section 02, James Hamilton 2026-04-23Form 42026-04-240001830755-26-000007Insider equity transaction reported since the proxy statement. Filing ↗
29Section 02, Hongbo Lu 2026-05-12Form 42026-05-140001767584-26-000002Insider equity transaction reported since the proxy statement. Filing ↗
30Section 02, Matthew Gregory Cohen 2026-06-15Form 42026-06-170002141314-26-000004Insider equity transaction reported since the proxy statement. Filing ↗
31Section 02, Adeoye Olukotun 2026-08-18Form 42026-08-200001242615-26-000002Insider equity transaction reported since the proxy statement. Filing ↗
32Section 02, Michael S. Perry 2026-08-18Form 42026-08-200001250379-26-000002Insider equity transaction reported since the proxy statement. Filing ↗
33Section 06, 2026 voteForm 8-K2026-03-200000879407-26-000037Item 5.07 · say-on-pay result. As reported: 40.97% (votes for as printed: 41,625,740). Filing ↗
34Section 06, 2025 voteForm 8-K2025-03-190001628280-25-013619Item 5.07 · say-on-pay result. As reported: 90.9% (votes for as printed: 75,327,072). Filing ↗
35Section 06, 2024 voteForm 8-K2024-03-190001628280-24-011930Item 5.07 · say-on-pay result. As reported: 94.34% (votes for as printed: 82,576,047). Filing ↗
36Section 01 trend, Δ column (computed)Computed——Δ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
37Section 03b vehicle mix (computed)Computed——RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio
38Section 09b board cost (computed)Computed——Cash 592,500 + equity 2,830,454 + all other 0 = 3,422,954, summed across the director compensation table rows.machine: formula: Σ = 3,422,954
39Halozyme Therapeutics, Section 10b CEO totalDEF 14A2026-03-230001159036-26-000041CEO total compensation as printed in Halozyme Therapeutics's own proxy. As printed: 23,166,223. Filing ↗machine: r3 · c48 · span 478282–478292
40Madrigal Pharmaceuticals, Section 10b CEO totalDEF 14A2026-04-280001308179-26-000352CEO total compensation as printed in Madrigal Pharmaceuticals's own proxy. As printed: 19,206,341. Filing ↗machine: r2 · c24 · span 791942–791952
41BridgeBio Pharma, Section 10b CEO totalDEF 14A2026-04-240001140361-26-016723CEO total compensation as printed in BridgeBio Pharma's own proxy. As printed: 14,944,585. Filing ↗machine: r2 · c21 · span 527521–527531
42Blueprint Medicines, Section 10b CEO totalDEF 14A2025-04-240001558370-25-005415CEO total compensation as printed in Blueprint Medicines's own proxy. As printed: 13,477,004. Filing ↗machine: span 1101152–1101162
43Ionis Pharmaceuticals, Section 10b CEO totalDEF 14A2026-04-230001140361-26-016388CEO total compensation as printed in Ionis Pharmaceuticals's own proxy. As printed: 13,350,777. Filing ↗
44BioCryst Pharmaceuticals, Section 10b CEO totalDEF 14A2026-04-230001628280-26-026822CEO total compensation as printed in BioCryst Pharmaceuticals's own proxy. As printed: 12,951,082. Filing ↗machine: span 512256–512266
45Ultragenyx Pharmaceuticals, Section 10b CEO totalDEF 14A2026-03-270001308179-26-000174CEO total compensation as printed in Ultragenyx Pharmaceuticals's own proxy. As printed: 11,405,535. Filing ↗machine: span 668997–669007
46Apellis Pharmaceuticals, Section 10b CEO totalDEF 14A2025-04-230000950170-25-056966CEO total compensation as printed in Apellis Pharmaceuticals's own proxy. As printed: 10,957,451. Filing ↗machine: r2 · c25 · span 951555–951565
47Arcus Biosciences, Section 10b CEO totalDEF 14A2026-04-210001724521-26-000025CEO total compensation as printed in Arcus Biosciences's own proxy. As printed: 9,656,813. Filing ↗machine: r2 · c48 · span 403740–403749
48IDEAYA Biosciences, Section 10b CEO totalDEF 14A2026-04-290001193125-26-191501CEO total compensation as printed in IDEAYA Biosciences's own proxy. As printed: 9,512,640. Filing ↗machine: r2 · c14 · span 627310–627319
49ARROWHEAD PHARMACEUTICALS, INC. (subject), Section 10b CEO totalDEF 14A2026-01-270000879407-26-000019CEO total compensation as printed in ARROWHEAD PHARMACEUTICALS, INC.'s own proxy. As printed: 9,029,861. Filing ↗machine: span 692475–692484
50Amicus Therapeutics, Section 10b CEO totalDEF 14A2025-04-240001140361-25-015479CEO total compensation as printed in Amicus Therapeutics's own proxy. As printed: 8,526,943. Filing ↗machine: r2 · c25 · span 736126–736136
51ACADIA Pharmaceuticals, Inc., Section 10b CEO totalDEF 14A2026-04-240001193125-26-174163CEO total compensation as printed in ACADIA Pharmaceuticals, Inc.'s own proxy. As printed: 8,256,518. Filing ↗
52Vir Biotechnology, Section 10b CEO totalDEF 14A2026-04-160001628280-26-025379CEO total compensation as printed in Vir Biotechnology's own proxy. As printed: 7,834,045. Filing ↗machine: t71 · r3 · c22 · span 625913–625922
53CRISPR Therapeutics AG, Section 10b CEO totalDEF 14A2026-04-210001193125-26-165158CEO total compensation as printed in CRISPR Therapeutics AG's own proxy. As printed: 7,678,477. Filing ↗machine: r2 · c25 · span 821649–821658
54Day One Biopharmaceuticals, Section 10b CEO totalDEF 14A2025-04-110001140361-25-013462CEO total compensation as printed in Day One Biopharmaceuticals's own proxy. As printed: 6,560,577. Filing ↗machine: r2 · c21 · span 526324–526333
55AnaptysBio, Section 10b CEO totalDEF 14A2026-06-290001193125-26-288408CEO total compensation as printed in AnaptysBio's own proxy. As printed: 6,133,943. Filing ↗machine: span 694406–694415
56Intellia Therapeutics, Section 10b CEO totalDEF 14A2026-04-300001193125-26-197283CEO total compensation as printed in Intellia Therapeutics's own proxy. As printed: 5,063,899. Filing ↗machine: r2 · c25 · span 749290–749299
57Denali Therapeutics, Section 10b CEO totalDEF 14A2026-04-210001714899-26-000054CEO total compensation as printed in Denali Therapeutics's own proxy. As printed: 4,751,515. Filing ↗machine: t25 · r2 · c25 · span 469605–469614
58Ironwood Pharmaceuticals, Section 10b CEO totalDEF 14A2026-04-280001104659-26-050325CEO total compensation as printed in Ironwood Pharmaceuticals's own proxy. As printed: 1,948,390. Filing ↗machine: r1 · c48 · span 584182–584191
59Section 10a, ACADIA Pharmaceuticals, Inc. reciprocityDEF 14A—0001193125-26-174163ACADIA Pharmaceuticals, Inc.'s most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
60Section 10a, AnaptysBio reciprocityDEF 14A—0001193125-26-288408AnaptysBio's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
61Section 10a, Blueprint Medicines reciprocityDEF 14A—0001558370-25-005415Blueprint Medicines's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
62Section 10a, BridgeBio Pharma reciprocityDEF 14A—0001140361-26-016723BridgeBio Pharma names ARROWHEAD PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗
63Section 10a, Day One Biopharmaceuticals reciprocityDEF 14A—0001140361-25-013462Day One Biopharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
64Section 10a, Denali Therapeutics reciprocityDEF 14A—0001714899-26-000054Denali Therapeutics's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
65Section 10a, Ultragenyx Pharmaceuticals reciprocityDEF 14A—0001308179-26-000174Ultragenyx Pharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
66Section 10a, Halozyme Therapeutics reciprocityDEF 14A—0001159036-26-000041Halozyme Therapeutics's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
67Section 10a, Ionis Pharmaceuticals reciprocityDEF 14A—0001140361-26-016388Ionis Pharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
68Section 10a, CRISPR Therapeutics AG reciprocityDEF 14A—0001193125-26-165158CRISPR Therapeutics AG names ARROWHEAD PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗
69Section 10a, Ironwood Pharmaceuticals reciprocityDEF 14A—0001104659-26-050325Ironwood Pharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
70Section 10a, IDEAYA Biosciences reciprocityDEF 14A—0001193125-26-191501IDEAYA Biosciences's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
71Section 10a, Amicus Therapeutics reciprocityDEF 14A—0001140361-25-015479Amicus Therapeutics's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
72Section 10a, Intellia Therapeutics reciprocityDEF 14A—0001193125-26-197283Intellia Therapeutics names ARROWHEAD PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗
73Section 10a, Madrigal Pharmaceuticals reciprocityDEF 14A—0001308179-26-000352Madrigal Pharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
74Section 10a, BioCryst Pharmaceuticals reciprocityDEF 14A—0001628280-26-026822BioCryst Pharmaceuticals names ARROWHEAD PHARMACEUTICALS, INC. in its own disclosed peer group (read from its most recent proxy). Filing ↗
75Section 10a, Vir Biotechnology reciprocityDEF 14A—0001628280-26-025379Vir Biotechnology's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗
76Section 10a, Apellis Pharmaceuticals reciprocityDEF 14A—0000950170-25-056966Apellis Pharmaceuticals's most recent proxy was read; its disclosed peer group does not include ARROWHEAD PHARMACEUTICALS, INC.. Filing ↗

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