Fiscal year 2025 executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.
Each company listed discloses ALNY in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named ALNY in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.
| Named executive officer | Salary | Bonus | Stock awards | Option awards | Non-equity incentive | Pension / NQDC | All other | Total |
|---|---|---|---|---|---|---|---|---|
| Yvonne Greenstreet | $1,404,200 | $0 | $5,512,500 | $4,363,380 | $3,562,500 | $0 | $25,020 | $14,867,600 |
| Chief Executive Officer | ||||||||
| Jeffrey Poulton | 724,400 | 0 | 3,988,480 | 1,178,220 | 950,300 | 0 | 22,400 | 6,863,800 |
| Executive Vice President, Chief Financial Officer | ||||||||
| Bryan Supran | 190,400 | 350,000 | 6,000,430 | 0 | 214,820 | 0 | 90,700 | 6,846,350 |
| Executive Vice President, Chief Legal Officer and Secretary | ||||||||
| Pushkal Garg | 767,900 | 0 | 3,687,650 | 940,050 | 1,072,500 | 0 | 22,400 | 6,490,500 |
| Executive Vice President, Chief Research and Development Officer | ||||||||
| Tolga Tanguler | 698,000 | 0 | 3,687,650 | 940,050 | 783,200 | 0 | 20,120 | 6,129,020 |
| Executive Vice President, Chief Commercial Officer | ||||||||
A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.
| Named executive officer | FY2025 total | FY2024 total | FY2023 total | Δ FY2024→2025 |
|---|---|---|---|---|
| Yvonne Greenstreet | $14,867,600 | — | — | — |
| Jeffrey Poulton | 6,863,800 | — | — | — |
| Bryan Supran | 6,846,350 | — | — | — |
| Pushkal Garg | 6,490,500 | — | — | — |
| Tolga Tanguler | 6,129,020 | — | — | — |
Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.
Every insider equity transaction reported on Form 4 after the 2025 proxy statement — acquisitions, dispositions, exercises, and withholdings — and therefore not reflected in any table in that document.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Amy W. Schulman | Director | 2026-05-13 | D | 11,250 | $0 | $0 | Derivative, Class A Common | Form 4 ↗ |
| Amy W. Schulman | Director | 2026-05-13 | A | 11,250 | 70 | 789,750 | Common | Form 4 ↗ |
| Dividend-equivalent accruals | 2026-05-20 | — | 13,330 | — | — | 9 insiders, 9 accrual rows | ||
| Dennis A. Ausiello | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Peter N. Kellogg | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Margaret A. Hamburg | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Stuart A. Arbuckle | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Olivier Brandicourt | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Colleen F. Reitan | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Amy W. Schulman | Director | 2026-05-20 | A | 838 | 0 | 0 | RSU | Form 4 ↗ |
| Charles Elliott Sigal | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 17 | 303 | 5,145 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 495 | 301 | 148,856 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 3,830 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | A | 3,830 | 0 | 0 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 921 | 298 | 274,191 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 1,175 | 299 | 351,219 | Common | Form 4 ↗ |
| Benjamin Cravatt | Director | 2026-06-01 | A | 4,393 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 1,222 | 300 | 366,441 | Common | Form 4 ↗ |
Transaction codes per Form 4: A acquisition · S open-market sale · F tax withholding · M option exercise · G gift. Value = shares × price as reported. Dividend-equivalent and fractional-share accrual rows (derivative Class A, under $10,000 and under 2,000 shares) are aggregated per date; every row appears in full below.
| Insider | Role | Transaction date | Code | Shares | Price | Value | Security | Source |
|---|---|---|---|---|---|---|---|---|
| Amy W. Schulman | Director | 2026-05-13 | D | 11,250 | $0 | $0 | Derivative, Class A Common | Form 4 ↗ |
| Amy W. Schulman | Director | 2026-05-13 | A | 11,250 | 70 | 789,750 | Common | Form 4 ↗ |
| Peter N. Kellogg | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Margaret A. Hamburg | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Dennis A. Ausiello | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Dennis A. Ausiello | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Stuart A. Arbuckle | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Peter N. Kellogg | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Margaret A. Hamburg | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Olivier Brandicourt | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Stuart A. Arbuckle | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Olivier Brandicourt | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Charles Elliott Sigal | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Colleen F. Reitan | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| Amy W. Schulman | Director | 2026-05-20 | A | 838 | 0 | 0 | RSU | Form 4 ↗ |
| Colleen F. Reitan | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Amy W. Schulman | Director | 2026-05-20 | A | 1,802 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| Charles Elliott Sigal | Director | 2026-05-20 | A | 671 | 0 | 0 | RSU | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-05-20 | A | 1,441 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 17 | 303 | 5,145 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 495 | 301 | 148,856 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 3,830 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | A | 3,830 | 0 | 0 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 921 | 298 | 274,191 | Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 1,175 | 299 | 351,219 | Common | Form 4 ↗ |
| Benjamin Cravatt | Director | 2026-06-01 | A | 4,393 | 0 | 0 | Derivative, Class A Common | Form 4 ↗ |
| David E.I. Pyott | Director | 2026-06-01 | D | 1,222 | 300 | 366,441 | Common | Form 4 ↗ |
| Executive | Award | Grant date | Threshold | Target | Granted | Maximum | Grant-date fair value |
|---|---|---|---|---|---|---|---|
| Yvonne Greenstreet | RSU | 2025-03-03 | — | — | 17,965 | — | $4,375,000 |
| Jeffrey Poulton | PSU | 2025-03-03 | 4,851 | 9,702 | — | 19,404 | 307,150 |
| Pushkal Garg | RSU | 2025-03-03 | — | — | 14,137 | — | 3,442,580 |
| Tolga Tanguler | OPTION | 2025-03-03 | — | — | 7,819 | — | 940,050 |
| Jeffrey Poulton | OPTION | 2025-03-03 | — | — | 9,800 | — | 1,178,220 |
| Pushkal Garg | OPTION | 2025-03-03 | — | — | 7,819 | — | 940,050 |
| Tolga Tanguler | PSU | 2025-03-03 | 3,871 | 7,741 | — | 15,482 | 245,070 |
| Tolga Tanguler | RSU | 2025-03-03 | — | — | 14,137 | — | 3,442,580 |
| Jeffrey Poulton | RSU | 2025-03-03 | — | — | 15,117 | — | 3,681,330 |
| Pushkal Garg | PSU | 2025-03-03 | 3,871 | 7,741 | — | 15,482 | 245,070 |
| Yvonne Greenstreet | PSU | 2025-03-03 | 17,965 | 35,930 | — | 71,860 | 1,137,500 |
| Yvonne Greenstreet | OPTION | 2025-03-03 | — | — | 36,293 | — | 4,363,380 |
| Bryan Supran | RSU | 2025-10-01 | — | — | 13,026 | — | 6,000,430 |
| Named executive officer | Time-vested (RSU) | Performance-vested (PSU) | Options / SARs | % performance-vested |
|---|---|---|---|---|
| Yvonne Greenstreet | $4,375,000 | $1,137,500 | $4,363,380 | 11.5% |
| Jeffrey Poulton | 3,681,330 | 307,150 | 1,178,220 | 5.9% |
| Pushkal Garg | 3,442,580 | 245,070 | 940,050 | 5.3% |
| Tolga Tanguler | 3,442,580 | 245,070 | 940,050 | 5.3% |
| Bryan Supran | 6,000,430 | 0 | 0 | 0.0% |
% performance-vested = PSU grant-date fair value ÷ (RSU + PSU + Options), a computed value with the derivation shown in the register.
| Executive | Award | Shares unvested | Exercise price | Market value unvested |
|---|---|---|---|---|
| Tolga Tanguler | Option | 5,220 | 152.61 | — |
| Pushkal Garg | Option | 3,703 | 190.01 | — |
| Jeffrey Poulton | RSU | 8,013 | — | 3,186,369 |
| Tolga Tanguler | Option | 1,151 | 147.47 | — |
| Jeffrey Poulton | RSU | 19,404 | — | 7,716,001 |
| Yvonne Greenstreet | RSU | 19,003 | — | 7,556,543 |
| Yvonne Greenstreet | RSU | 15,836 | — | 6,297,185 |
| Yvonne Greenstreet | Option | 11,493 | 190.01 | — |
| Yvonne Greenstreet | Option | 1,985 | 147.47 | — |
| Jeffrey Poulton | Option | 1,151 | 147.47 | — |
| Yvonne Greenstreet | RSU | 24,867 | — | 9,888,363 |
| Yvonne Greenstreet | RSU | 17,965 | — | 7,143,782 |
| Yvonne Greenstreet | RSU | 71,860 | — | 28,575,129 |
| Pushkal Garg | RSU | 8,013 | — | 3,186,369 |
| Jeffrey Poulton | Option | 9,800 | 243.53 | — |
| Yvonne Greenstreet | Option | 26,097 | 152.61 | — |
| Jeffrey Poulton | Option | 8,504 | 152.61 | — |
| Bryan Supran | RSU | 13,026 | — | 5,179,789 |
| Tolga Tanguler | Option | 3,235 | 190.01 | — |
| Yvonne Greenstreet | RSU | 5,921 | — | 2,354,486 |
| Jeffrey Poulton | Option | 3,703 | 190.01 | — |
| Jeffrey Poulton | RSU | 15,117 | — | 6,011,275 |
| Pushkal Garg | RSU | 1,908 | — | 758,716 |
| Tolga Tanguler | RSU | 14,137 | — | 5,621,578 |
| Tolga Tanguler | RSU | 15,482 | — | 6,156,417 |
| Tolga Tanguler | RSU | 3,800 | — | 1,511,070 |
| Tolga Tanguler | RSU | 3,167 | — | 1,259,358 |
| Pushkal Garg | RSU | 3,800 | — | 1,511,070 |
| Pushkal Garg | Option | 1,508 | 147.47 | — |
| Pushkal Garg | RSU | 3,167 | — | 1,259,358 |
| Pushkal Garg | Option | 7,819 | 243.53 | — |
| Pushkal Garg | RSU | 15,482 | — | 6,156,417 |
| Pushkal Garg | RSU | 14,137 | — | 5,621,578 |
| Tolga Tanguler | RSU | 7,000 | — | 2,783,550 |
| Jeffrey Poulton | RSU | 6,193 | — | 2,462,646 |
| Jeffrey Poulton | RSU | 5,160 | — | 2,051,874 |
| Jeffrey Poulton | RSU | 1,908 | — | 758,716 |
| Yvonne Greenstreet | Option | 36,293 | 243.53 | — |
| Pushkal Garg | Option | 5,220 | 152.61 | — |
| Tolga Tanguler | Option | 7,819 | 243.53 | — |
| Tolga Tanguler | RSU | 1,666 | — | 662,485 |
Align executive interests with the drivers of growth and stockholder returns; Incentivize the execution of company strategy and primary business goals; Attract and retain talented executives with diverse expertise, skills, and background with market competitive pay; Drive growth of sustainable long-term stockholder value
| CEO STI target (% of salary) | 125% |
|---|---|
| CEO LTI target (% of salary) | — |
| Independent consultant | Pay Governance |
| Clawback policy | true |
| Anti-hedging | true |
| Anti-pledging | True |
| Meeting year | Meeting date | For | Against | Abstain | Support | Outcome |
|---|---|---|---|---|---|---|
| 2026 | 2026-05-20 | 111,772,389 | 8,552,534 | 41,495 | 92.89% | Passed |
| 2025 | 2025-05-08 | 111,725,907 | 6,909,706 | 29,274 | 94.18% | Passed |
| 2024 | 2024-05-16 | 106,783,262 | 6,133,628 | 29,162 | 94.57% | Passed |
| 2023 | 2023-05-18 | 109,696,830 | 4,017,474 | 18,098 | 96.47% | Passed |
| 2022 | 2022-05-18 | 95,318,086 | 10,517,203 | 24,526 | 90.06% | Passed |
| 2021 | 2021-05-18 | 81,382,437 | 20,146,079 | 186,307 | 80.16% | Passed |
Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.
| Meeting year | Meeting date | Approval — company's computation |
|---|---|---|
| 2026 | 2026-05-20 | 92.89%a |
| 2025 | 2025-05-08 | 94.18%b |
| 2024 | 2024-05-16 | 94.57%c |
a. Approved under the standard stated in the filing — “Abstentions and broker non-votes will have no effect on the outcome of Proposal 2.”.
b. Approved under the standard stated in the filing — “Abstentions and broker non-votes will not be counted as shares voting on this matter and accordingly will have no effect on the approval of this Proposal 3.”.
c. Approved under the standard stated in the filing — “Accordingly, abstentions and broker non-votes, if any, would have no effect on the vote for any of the Proposals to be considered at the annual meeting, because these Proposals are based on a percentage of the votes that are actually cast at the annual meeting.”.
Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.
| Ratio (CEO : median employee) | 48 : 1 |
|---|---|
| CEO total compensation | $14,867,600 |
| Median employee compensation | $312,180 |
| Director | Cash fees | Stock awards | Option awards | Non-equity incentive | All other | Total |
|---|---|---|---|---|---|---|
| Michael W. BonneyNot independent · Departed during FY | $55,270 | $360,320 | $325,540 | $0 | — | $741,130 |
| Amy W. SchulmanIndependent · Board Chair · Nominating and Corporate Governance · People, Culture and Compensation | 141,460 | 200,220 | 199,630 | 0 | — | 541,310 |
| Colleen F. ReitanIndependent · Audit · People, Culture and Compensation (Chair) | 92,500 | 200,220 | 199,630 | 0 | — | 492,350 |
| Elliott Sigal, M.D., Ph.DIndependent · People, Culture and Compensation · Science and Technology | 86,460 | 200,220 | 199,630 | 0 | — | 486,310 |
| Peter N. KelloggIndependent · Audit (Chair) | 85,000 | 200,220 | 199,630 | 0 | — | 484,850 |
| Olivier Brandicourt, M.DIndependent · Audit · People, Culture and Compensation | 82,500 | 200,220 | 199,630 | 0 | — | 482,350 |
| David E.I. PyottIndependent · Nominating and Corporate Governance · Science and Technology | 80,000 | 200,220 | 199,630 | 0 | — | 479,850 |
| Dennis A. Ausiello, M.DIndependent · Science and Technology | 80,000 | 200,220 | 199,630 | 0 | — | 479,850 |
| Carolyn R. Bertozzi, Ph.DIndependent · Science and Technology · Departed during FY | 73,700 | 200,220 | 199,630 | 0 | — | 473,550 |
| Margaret A. Hamburg, M.DIndependent · Nominating and Corporate Governance · Science and Technology | 70,000 | 200,220 | 199,630 | 0 | — | 469,850 |
| Phillip A. Sharp, Ph.DIndependent · Science and Technology · Departed during FY | 45,920 | — | — | 0 | 7,010 | 52,930 |
| Stuart A. ArbuckleIndependent · Science and Technology · Newly elected | 0 | 0 | 0 | 0 | 0 | 0 |
| Yvonne L. Greenstreet, M.DEmployee director | 0 | 0 | 0 | — | 0 | 0 |
| Annual cash retainer | $60,000 |
|---|---|
| Annual equity retainer | $400,000 |
| Per board meeting fee | — |
| Committee chair fees (audit / comp / nom-gov) | 65,000 |
| Stock ownership guideline | — |
| Component | FY2025 |
|---|---|
| Cash retainers and fees | $892,810 |
| Equity awards (grant-date value) | $2,162,300 |
| All other compensation | $7,010 |
| Total cost of the board | $3,062,120 |
Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.
The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.
Of the companies Alnylam Pharmaceuticals, Inc. names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.
Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including Alnylam Pharmaceuticals, Inc..
Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.
| Rank | Company | FY | Chief executive | Salary | Stock awards | Option awards | Non-equity incentive | Total |
|---|---|---|---|---|---|---|---|---|
| 1 | Incyte Corporation | 2025 | William Meury | $647,260 | $27,509,657 | $2,573,998 | $1,300,000 | $32,085,952 |
| 2 | Gilead Sciences, Inc. | 2025 | Daniel O'Day | 1,795,192 | 15,238,402 | 4,500,060 | 4,848,120 | 28,437,198 |
| 3 | Biogen Inc. | 2025 | Christopher Viehbacher | 1,727,885 | 18,368,875 | 0 | 3,190,875 | 23,646,004 |
| 4 | BioMarin Pharmaceutical Inc. | 2025 | Alexander Hardy | 1,130,769 | 16,833,629 | 1,909,310 | 1,644,500 | 21,927,563 |
| 5 | Vertex Pharmaceuticals Incorporated | 2025 | Reshma Kewalramani | 1,600,000 | 15,002,270 | 0 | 4,118,640 | 21,144,261 |
| 6 | Moderna, Inc. | 2025 | Stéphane Bancel | 1,677,739 | 6,897,455 | 6,897,425 | 4,302,360 | 19,932,217 |
| 7 | United Therapeutics Corporation | 2025 | Martine Rothblatt | 1,545,005 | 6,067,990 | 6,075,804 | 4,281,875 | 18,038,972 |
| 8 | Exact Sciences Corporation | 2024 | Kevin Conroy | 1,083,368 | 13,496,138 | 0 | 712,329 | 15,539,378 |
| 9 | Alnylam Pharmaceuticals, Inc. | 2025 | Yvonne Greenstreet | 1,404,200 | 5,512,500 | 4,363,380 | 3,562,500 | 14,867,600 |
| 10 | Neurocrine Biosciences, Inc. | 2025 | Kyle Gano | 920,000 | 5,750,023 | 5,750,006 | 0 | 13,448,935 |
| 11 | Regeneron Pharmaceuticals, Inc. | 2025 | Leonard Schleifer | 1,979,922 | 0 | 0 | 3,682,655 | 7,280,549 |
Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.
| Company | Annual incentive payout | Long-term vehicle mix | PSU measures include TSR | Compensation consultant |
|---|---|---|---|---|
| Alnylam Pharmaceuticals, Inc. | 200% | PSU 50 · RSU 25 · Options 25 | No | Pay Governance |
| Biogen Inc. | 127% | PSU 60 · RSU 40 | Yes | Pay Governance |
| BioMarin Pharmaceutical Inc. | 130% | PSU 66 · RSU 21 · Options 13 | Yes — Relative TSR | Aon Human Capital Solutions |
| Exact Sciences Corporation | 47% | PSU 60 · RSU 40 | No | Aon |
| Gilead Sciences, Inc. | 180% | PSU 50 · Options 25 · RSU 25 | Yes — Relative TSR | FW Cook |
| Incyte Corporation | 138.6% | PSU 60 · Options 20 · RSU 20 | Yes — relative total shareholder return (TSR) | Aon |
| Moderna, Inc. | 170% | PSU 50 · Options 50 | No | Pay Governance LLC |
| Neurocrine Biosciences, Inc. | 105% | Options 50 · PSU 30 · RSU 20 | No | Frederic W. Cook & Co., Inc. |
| Regeneron Pharmaceuticals, Inc. | 155% | Options 60 · RSA 40 | not disclosed | Pay Governance LLC |
| United Therapeutics Corporation | 221% | Options 50 · PSU 50 | No | Aon Human Capital Solutions |
| Vertex Pharmaceuticals Incorporated | not disclosed | PSU 55 · RSU 45 | No | not disclosed |
Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.
Answers are drawn only from the figures disclosed in this brief and cited to their location in the source filing. Where a figure required for an answer is not disclosed, that is stated rather than estimated.
Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.
| # | Supports | Document | Filed | Accession | Location in document |
|---|---|---|---|---|---|
| 1 | Section 01, Yvonne Greenstreet | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Summary Compensation Table”. As printed: 14,867,600. Filing ↗machine: span 1294691–1294701 |
| 2 | Section 01, Jeffrey Poulton | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Summary Compensation Table”. As printed: 6,863,800. Filing ↗machine: span 1304525–1304534 |
| 3 | Section 01, Bryan Supran | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Summary Compensation Table”. As printed: 6,846,350. Filing ↗machine: span 1314212–1314221 |
| 4 | Section 01, Pushkal Garg | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Summary Compensation Table”. As printed: 6,490,500. Filing ↗machine: span 1317931–1317940 |
| 5 | Section 01, Tolga Tanguler | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Summary Compensation Table”. As printed: 6,129,020. Filing ↗machine: span 1328192–1328201 |
| 6 | Section 03, Yvonne Greenstreet RSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r6 · c14 · span 1398532–1398541 |
| 7 | Section 03, Jeffrey Poulton PSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r9 · c16 · span 1404159–1404166 |
| 8 | Section 03, Pushkal Garg RSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r19 · c14 · span 1418481–1418490 |
| 9 | Section 03, Tolga Tanguler OPTION | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r21 · c15 · span 1422855–1422862 |
| 10 | Section 03, Jeffrey Poulton OPTION | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r8 · c15 · span 1402126–1402135 |
| 11 | Section 03, Pushkal Garg OPTION | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r17 · c15 · span 1414929–1414936 |
| 12 | Section 03, Tolga Tanguler PSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r22 · c16 · span 1425311–1425318 |
| 13 | Section 03, Tolga Tanguler RSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r23 · c14 · span 1427683–1427692 |
| 14 | Section 03, Jeffrey Poulton RSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r10 · c14 · span 1405680–1405689 |
| 15 | Section 03, Pushkal Garg PSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r18 · c16 · span 1416960–1416967 |
| 16 | Section 03, Yvonne Greenstreet PSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r5 · c16 · span 1396634–1396643 |
| 17 | Section 03, Yvonne Greenstreet OPTION | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r4 · c15 · span 1394174–1394183 |
| 18 | Section 03, Bryan Supran RSU | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Grants of Plan-Based Awards” · grants of plan-based awards table. Filing ↗machine: t141 · r15 · c14 · span 1411364–1411373 |
| 19 | Section 07, pay ratio | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “CEO Pay Ratio”. As printed: 48 : 1. Filing ↗machine: span 1682859–1682861 |
| 20 | Section 08, Michael W. Bonney | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 741,130. Filing ↗machine: t78 · r4 · c10 · span 655261–655268 |
| 21 | Section 08, Amy W. Schulman | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 541,310. Filing ↗machine: t78 · r10 · c10 · span 666805–666812 |
| 22 | Section 08, Colleen F. Reitan | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 492,350. Filing ↗machine: t78 · r9 · c10 · span 664761–664768 |
| 23 | Section 08, Elliott Sigal, M.D., Ph.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 486,310. Filing ↗machine: t78 · r12 · c10 · span 671488–671495 |
| 24 | Section 08, Peter N. Kellogg | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 484,850. Filing ↗machine: t78 · r7 · c10 · span 660922–660929 |
| 25 | Section 08, Olivier Brandicourt, M.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 482,350. Filing ↗machine: t78 · r5 · c10 · span 657064–657071 |
| 26 | Section 08, David E.I. Pyott | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 479,850. Filing ↗machine: t78 · r8 · c10 · span 662966–662973 |
| 27 | Section 08, Dennis A. Ausiello, M.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 479,850. Filing ↗machine: t78 · r2 · c10 · span 650993–651000 |
| 28 | Section 08, Carolyn R. Bertozzi, Ph.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 473,550. Filing ↗machine: t78 · r3 · c10 · span 653022–653029 |
| 29 | Section 08, Margaret A. Hamburg, M.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 469,850. Filing ↗machine: t78 · r6 · c10 · span 659117–659124 |
| 30 | Section 08, Phillip A. Sharp, Ph.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 52,930. Filing ↗machine: t78 · r11 · c10 · span 669061–669067 |
| 31 | Section 08, Stuart A. Arbuckle | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 0. Filing ↗ |
| 32 | Section 08, Yvonne L. Greenstreet, M.D | DEF 14A | 2026-04-06 | 0001628280-26-023923 | Section “Director Compensation”. As printed: 0. Filing ↗ |
| 33 | Section 02, Amy W. Schulman 2026-05-13 | Form 4 | 2026-05-14 | 0001178670-26-000017 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 34 | Section 02, Amy W. Schulman 2026-05-13 | Form 4 | 2026-05-14 | 0001178670-26-000017 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 35 | Section 02, Peter N. Kellogg 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000038 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 36 | Section 02, Margaret A. Hamburg 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000037 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 37 | Section 02, Dennis A. Ausiello 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000035 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 38 | Section 02, Dennis A. Ausiello 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000035 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 39 | Section 02, Stuart A. Arbuckle 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000034 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 40 | Section 02, Peter N. Kellogg 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000038 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 41 | Section 02, Margaret A. Hamburg 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000037 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 42 | Section 02, Olivier Brandicourt 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000036 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 43 | Section 02, Stuart A. Arbuckle 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000034 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 44 | Section 02, David E.I. Pyott 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000039 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 45 | Section 02, Olivier Brandicourt 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000036 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 46 | Section 02, Charles Elliott Sigal 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000042 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 47 | Section 02, Colleen F. Reitan 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000040 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 48 | Section 02, Amy W. Schulman 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000041 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 49 | Section 02, Colleen F. Reitan 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000040 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 50 | Section 02, Amy W. Schulman 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000041 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 51 | Section 02, Charles Elliott Sigal 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000042 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 52 | Section 02, David E.I. Pyott 2026-05-20 | Form 4 | 2026-05-22 | 0001178670-26-000039 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 53 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 54 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 55 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 56 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 57 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 58 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 59 | Section 02, Benjamin Cravatt 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000047 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 60 | Section 02, David E.I. Pyott 2026-06-01 | Form 4 | 2026-06-03 | 0001178670-26-000048 | Insider equity transaction reported since the proxy statement. Filing ↗ |
| 61 | Section 06, 2026 vote | Form 8-K | 2026-05-27 | 0001628280-26-038499 | Item 5.07 · say-on-pay result. As reported: 92.89% (votes for as printed: 111,772,389). Filing ↗ |
| 62 | Section 06, 2025 vote | Form 8-K | 2025-05-13 | 0001178670-25-000062 | Item 5.07 · say-on-pay result. As reported: 94.18% (votes for as printed: 111,725,907). Filing ↗ |
| 63 | Section 06, 2024 vote | Form 8-K | 2024-05-20 | 0001178670-24-000027 | Item 5.07 · say-on-pay result. As reported: 94.57% (votes for as printed: 106,783,262). Filing ↗ |
| 64 | Section 03b vehicle mix (computed) | Computed | — | computed | RSU / PSU / Options grant-date fair values summed per officer from the grants table; % performance-vested = PSU ÷ (RSU+PSU+Options).machine: formula: sums + PSU ratio |
| 65 | Section 09b board cost (computed) | Computed | — | computed | Cash 892,810 + equity 2,162,300 + all other 7,010 = 3,062,120, summed across the director compensation table rows.machine: formula: Σ = 3,062,120 |
| 66 | Incyte Corporation, Section 10b CEO total | DEF 14A | 2026-04-28 | 0000879169-26-000031 | CEO total compensation as printed in Incyte Corporation's own proxy. As printed: 32,085,952. Filing ↗machine: t91 · r2 · c16 · span 637817–637827 |
| 67 | Gilead Sciences, Inc., Section 10b CEO total | DEF 14A | 2026-03-20 | 0001308179-26-000106 | CEO total compensation as printed in Gilead Sciences, Inc.'s own proxy. As printed: 28,437,198. Filing ↗machine: t414 · r1 · c29 · span 989582–989592 |
| 68 | Biogen Inc., Section 10b CEO total | DEF 14A | 2026-04-28 | 0001193125-26-187303 | CEO total compensation as printed in Biogen Inc.'s own proxy. As printed: 23,646,004. Filing ↗machine: r2 · c16 · span 1174380–1174391 |
| 69 | BioMarin Pharmaceutical Inc., Section 10b CEO total | DEF 14A | 2026-04-21 | 0001628280-26-026290 | CEO total compensation as printed in BioMarin Pharmaceutical Inc.'s own proxy. As printed: 21,927,563. Filing ↗machine: span 1384905–1384915 |
| 70 | Vertex Pharmaceuticals Incorporated, Section 10b CEO total | DEF 14A | 2026-04-02 | 0000875320-26-000153 | CEO total compensation as printed in Vertex Pharmaceuticals Incorporated's own proxy. As printed: 21,144,261. Filing ↗machine: r2 · c13 · span 2942799–2942809 |
| 71 | Moderna, Inc., Section 10b CEO total | DEF 14A | 2026-03-16 | 0001308179-26-000081 | CEO total compensation as printed in Moderna, Inc.'s own proxy. As printed: 19,932,217. Filing ↗machine: span 1132888–1132898 |
| 72 | United Therapeutics Corporation, Section 10b CEO total | DEF 14A | 2026-04-29 | 0001082554-26-000009 | CEO total compensation as printed in United Therapeutics Corporation's own proxy. As printed: 18,038,972. Filing ↗machine: span 1993726–1993736 |
| 73 | Exact Sciences Corporation, Section 10b CEO total | DEF 14A | 2025-04-29 | 0001124140-25-000034 | CEO total compensation as printed in Exact Sciences Corporation's own proxy. As printed: 15,539,378. Filing ↗machine: span 1077855–1077865 |
| 74 | Alnylam Pharmaceuticals, Inc. (subject), Section 10b CEO total | DEF 14A | 2026-04-06 | 0001628280-26-023923 | CEO total compensation as printed in Alnylam Pharmaceuticals, Inc.'s own proxy. As printed: 14,867,600. Filing ↗machine: span 1294691–1294701 |
| 75 | Neurocrine Biosciences, Inc., Section 10b CEO total | DEF 14A | 2026-04-15 | 0000914475-26-000015 | CEO total compensation as printed in Neurocrine Biosciences, Inc.'s own proxy. As printed: 13,448,935. Filing ↗machine: t50 · r4 · c7 · span 847947–847957 |
| 76 | Regeneron Pharmaceuticals, Inc., Section 10b CEO total | DEF 14A | 2026-04-24 | 0001308179-26-000340 | CEO total compensation as printed in Regeneron Pharmaceuticals, Inc.'s own proxy. As printed: 7,280,549. Filing ↗machine: r3 · c10 · span 3335980–3335989 |
| 77 | Section 10a, Gilead Sciences, Inc. reciprocity | DEF 14A | — | 0001308179-26-000106 | Gilead Sciences, Inc.'s most recent proxy was read; its disclosed peer group does not include Alnylam Pharmaceuticals, Inc.. Filing ↗ |
| 78 | Section 10a, Moderna, Inc. reciprocity | DEF 14A | — | 0001308179-26-000081 | Moderna, Inc. names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 79 | Section 10a, Vertex Pharmaceuticals Incorporated reciprocity | DEF 14A | — | 0000875320-26-000153 | Vertex Pharmaceuticals Incorporated's most recent proxy was read; its disclosed peer group does not include Alnylam Pharmaceuticals, Inc.. Filing ↗ |
| 80 | Section 10a, Neurocrine Biosciences, Inc. reciprocity | DEF 14A | — | 0000914475-26-000015 | Neurocrine Biosciences, Inc. names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 81 | Section 10a, United Therapeutics Corporation reciprocity | DEF 14A | — | 0001082554-26-000009 | United Therapeutics Corporation names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 82 | Section 10a, Regeneron Pharmaceuticals, Inc. reciprocity | DEF 14A | — | 0001308179-26-000340 | Regeneron Pharmaceuticals, Inc. names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 83 | Section 10a, Exact Sciences Corporation reciprocity | DEF 14A | — | 0001124140-25-000034 | Exact Sciences Corporation names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |
| 84 | Section 10a, BioMarin Pharmaceutical Inc. reciprocity | DEF 14A | — | 0001628280-26-026290 | BioMarin Pharmaceutical Inc. names Alnylam Pharmaceuticals, Inc. in its own disclosed peer group (read from its most recent proxy). Filing ↗ |