Velarion · Company Intelligence
Compensation Brief
Fiscal year 2025 · Filings through 2026-06-04

Stoke Therapeutics (STOK)

Fiscal year 2025 executive and director compensation, incentive-plan design, equity activity, and governance — every figure in this brief is traceable to its exact location in the company’s SEC filing — the document, the section, the page, and the table, linked directly.

$27,031,655
Ian Smith total, FY2025
99th
CEO pay percentile vs peers
CEO-to-median pay ratio
72.87%
Say-on-pay support, latest vote
Companies that benchmark against STOK
9 companies name STOK as a compensation peer

Each company listed discloses STOK in its own benchmarking peer group, as disclosed in each company's most recent proxy statement within the last two proxy seasons. Two companies are therefore absent by design: one that named STOK in an earlier year and no longer does, and one whose own most recent disclosure is older than the last two seasons.

01

Summary Compensation Table — fiscal year 2025

Named executive officerSalaryBonusStock awardsOption awardsNon-equity incentivePension / NQDCAll otherTotal
Ian Smith$170,625$1,197,125$11,590,000$14,035,067$0$0$38,838$27,031,655
Chief Executive Officer
Edward Kaye148,72601,199,5201,298,13800587,6583,234,043
Former Chief Executive Officer
Jason Hoitt494,4010333,2001,121,337306,000015,0172,269,955
Chief Patient Officer
Thomas Leggett496,3750491,470534,881297,82509,8241,830,375
Chief Financial Officer

A dash means the company reported no figure in that column; 0 means it reported zero. Figures are as printed in the filing, without adjustment.

Three-year trend — total compensation per named executive

Named executive officerFY2025 totalFY2024 totalFY2023 totalΔ FY20242025
Ian Smith$27,031,655
Edward Kaye3,234,0435,612,120−2,378,077
Jason Hoitt2,269,955
Thomas Leggett1,830,3754,520,386−2,690,011

Prior-year totals as disclosed in the corresponding proxy; deltas are computed values with the derivation shown in the register.

02

Equity transactions since the proxy statement was filed

No insider equity transactions reported since the proxy statement.

04

Outstanding equity awards at fiscal year-end 2025

ExecutiveAwardShares unvestedExercise priceMarket value unvested
SmithRSU380,000$12,061,200
Edward KayeRSU78,7502,499,525
Edward KayeRSU71,0002,253,540
Thomas LeggettRSU59,0001,872,660
Jason HoittRSU40,0001,269,600
Edward KayeRSU26,250833,175
Edward KayeOption19,25020.34
SmithOption24,0854.76
SmithOption570,00030.5
SmithOption7,63916.41
SmithOption238,4208.33
Thomas LeggettOption239,37114.13
Jason HoittOption48,7508.33
Thomas LeggettOption72,3138.33
Jason HoittOption154,58412.21
Jason HoittOption43,33414.25
Jason HoittOption78,75011.7
Edward KayeOption542,8010.6
Edward KayeOption468,3822.19
Edward KayeOption197,00020.25
Edward KayeOption41,7637.07
Edward KayeOption66,5639.15
Edward KayeOption89,43814.17
Edward KayeOption37,5008.33
05

Incentive-plan design — the Compensation Discussion & Analysis

The company's compensation program is designed to motivate and reward executive officers for achieving multi-year strategic goals and delivering sustained long-term value to shareholders. As a pre-commercial biopharmaceutical company, success is measured by the achievement of developmental, research, and operational milestones rather than revenue or profits, with a strong emphasis on aligning executive interests with stockholders through equity awards.

CEO STI target (% of salary)
CEO LTI target (% of salary)
Independent consultantAon
Clawback policytrue
Anti-hedgingtrue
Anti-pledgingtrue
06

Say-on-pay — recent advisory votes

Meeting yearMeeting dateForAgainstAbstainSupportOutcome
20262026-06-0336,436,27513,565,29329,41572.87%Passed
20252025-06-0330,543,5142,882,90718,71591.38%Passed
20232023-10-2423,393,1358,352,19126,57773.69%Passed

Rows are labeled by annual-meeting year, with the meeting date beside each; the vote held in a given year acts on the prior fiscal year's compensation.

Say-on-pay — history, company's computation

Meeting yearMeeting dateApproval — company's computation
20262026-06-0372.87%a
20252025-06-0391.38%b
20232023-10-2473.69%c

a. Voting standard not stated in the filing.

b. Voting standard not stated in the filing.

c. Voting standard not stated in the filing.

Approval percentages are the company's own reported computations under its own stated standard, not recomputed by Velarion. Where a company does not state a standard, none is assumed.

08

Director compensation — fiscal year 2025

DirectorCash feesStock awardsOption awardsNon-equity incentiveAll otherTotal
Arthur O. TzianabosIndependent$41,657$0$737,121$778,778
Arthur O. Tzianabos, Ph.DIndependent · Board Chair · Audit · Compensation · Research and Development41,6570737,121778,778
Jennifer C. Burstein, CPAIndependent · Audit (Chair)60,000223,3380283,338
Julie Anne SmithIndependent · Compensation · Audit60,000223,3380283,338
Jennifer C. BursteinIndependent60,000223,3380283,338
Arthur A. LevinIndependent57,912223,3380281,249
Arthur A. Levin, Ph.DIndependent · Nominating and Corporate Governance · Research and Development57,912223,3380281,249
Garry E. MenzelIndependent57,500223,3380280,838
Seth L. Harrison, M.DIndependent · Research and Development · Compensation47,500223,3380270,838
Adrian R. Krainer, Ph.DIndependent · Nominating and Corporate Governance · Research and Development45,000223,3380268,338
Adrian R. KrainerIndependent45,000223,3380268,338
Ian F. SmithEmployee director0
Edward M. Kaye, M.DNot independent · Research and Development
09

Board fee structure and ownership guideline

Annual cash retainer$40,000
Annual equity retainer$224,000
Per board meeting fee
Committee chair fees (audit / comp / nom-gov)20,000 / 15,000 / 10,000
Stock ownership guideline
09b

Total cost of the board

ComponentFY2025
Cash retainers and fees$574,138
Equity awards (grant-date value)$0
All other compensation$1,474,242
Total cost of the board$2,048,380

Computed as the sum of the director compensation table rows above; inputs and formula shown in the register.

10

Disclosed peer group — fiscal year 2025

The compensation peer group as the company disclosed it in its own proxy — the reference set behind the percentile above.

10a

Peer reciprocity

Of the companies Stoke Therapeutics names as compensation peers, which name it back in their own disclosed peer groups. A peer set the market reciprocates reads differently from one selected in a single direction.

Reciprocity shown where the peer's own current proxy has been read — each mark is cited in the register to that peer's filing. A dash means the peer's current proxy was read and names no reciprocal group including Stoke Therapeutics.

10b

Chief executive pay against the peer group

Most recent fiscal-year chief executive compensation at each disclosed peer, taken from that company's own proxy statement.

RankCompanyFYChief executiveSalaryStock awardsOption awardsNon-equity incentiveTotal
1Stoke Therapeutics2025Ian Smith$170,625$11,590,000$14,035,067$0$27,031,655
2Allogene Therapeutics2025David Chang724,0002,409,5372,588,329400,0106,136,093
3Beam Therapeutics2025John Evans755,0001,513,5752,876,754662,5135,818,525
4Cullinan Therapeutics2025Nadim Ahmed698,4761,697,4002,234,340419,0865,100,006
5Poseida Therapeutics2023Mark Gergen611,6671,442,2851,413,936336,4203,818,018
6Annexon2025Douglas Love670,83302,522,260371,2503,579,202
7Rocket Pharmaceuticals2025Gaurav Shah671,076806,7511,613,377403,0483,510,241
8Nkarta2025Paul Hastings674,384236,2501,711,957344,9472,978,038
9Fate Therapeutics2025Bahram Valamehr600,00001,283,868360,0002,248,568
10Lineage Cell Therapeutics2025Brian Culley691,8000882,970518,9002,111,170
114D Molecular Therapeutics2025David Kirn667,2520822,750560,5972,051,343
12Alector2025Arnon Rosenthal678,100422,876558,216325,4881,995,018
13Caribou Biosciences2025Rachel Haurwitz667,534192,818654,54101,840,965
14Arcturus Therapeutics2025Joseph Payne750,0000941,00001,691,000

Each peer's compensation is from its most recently filed proxy; fiscal years differ by company. Each peer's figures come from its own filings; the subject company is highlighted. Peers whose chief executive compensation is outside our coverage universe are stated as such, never left blank.

10c

Incentive design against the same peers

CompanyAnnual incentive payoutLong-term vehicle mixPSU measures include TSRCompensation consultant
Stoke Therapeuticsnot disclosednot disclosednot disclosedAon
4D Molecular Therapeutics140%Options 100not disclosedRadford (part of the Rewards Solutions practice at Aon plc)
Alector80%not disclosednot disclosedPearl Meyer & Partners, LLC
Allogene Therapeutics85%Options 55 · RSU 25 · PSU 20NoCompensia
Annexonnot disclosednot disclosednot disclosednot disclosed
Arcturus Therapeuticsnot disclosedOptions 100not disclosednot disclosed
Beam Therapeutics135%Options 66 · RSU 34not disclosedPay Governance LLC
Caribou Biosciences85%not disclosednot disclosedAlpine Rewards, LLC
Cullinan Therapeuticsnot disclosednot disclosednot disclosedCompensia (through June 2025); Pay Governance (since June 2025)
Fate Therapeutics100%Options 100NoAon's Human Capital Solutions practice (Radford)
Lineage Cell Therapeuticsnot disclosednot disclosednot disclosedAnderson
Nkartanot disclosednot disclosednot disclosedAon Consulting, Inc.
Poseida Therapeuticsnot disclosednot disclosednot disclosedAon
Rocket Pharmaceuticalsnot disclosednot disclosednot disclosedSemler Brossy

Read from each company's Compensation Discussion and Analysis: annual incentive payout as a percentage of target, the disclosed long-term vehicle mix, whether performance-share measures include a total shareholder return component, and the retained compensation consultant. “Not disclosed” appears only where the company's filing does not state the item.

11

Source register

Each figure's location is given both for the eye (section · page · table · row · column) and for a script (table/row/column index and exact character span in the filed document). Any figure can be independently confirmed against the source.

#SupportsDocumentFiledAccessionLocation in document
1Section 01, Ian SmithDEF 14A2026-04-220001193125-26-170362Section “Executive Compensation”. As printed: 27,031,655. Filing ↗machine: r2 · c31 · span 335841–335851
2Section 01, Edward KayeDEF 14A2026-04-220001193125-26-170362Section “Executive Compensation”. As printed: 3,234,043. Filing ↗machine: r11 · c31 · span 349156–349165
3Section 01, Jason HoittDEF 14A2026-04-220001193125-26-170362Section “Executive Compensation”. As printed: 2,269,955. Filing ↗machine: r8 · c31 · span 344916–344925
4Section 01, Thomas LeggettDEF 14A2026-04-220001193125-26-170362Section “Executive Compensation”. As printed: 1,830,375. Filing ↗machine: r5 · c31 · span 339918–339927
5Section 08, Arthur O. TzianabosDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 778,778. Filing ↗
6Section 08, Arthur O. Tzianabos, Ph.DDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 778,778. Filing ↗
7Section 08, Jennifer C. Burstein, CPADEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 283,338. Filing ↗
8Section 08, Julie Anne SmithDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 283,338. Filing ↗
9Section 08, Jennifer C. BursteinDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 283,338. Filing ↗
10Section 08, Arthur A. LevinDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 281,249. Filing ↗
11Section 08, Arthur A. Levin, Ph.DDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 281,249. Filing ↗
12Section 08, Garry E. MenzelDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 280,838. Filing ↗
13Section 08, Seth L. Harrison, M.DDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 270,838. Filing ↗
14Section 08, Adrian R. Krainer, Ph.DDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 268,338. Filing ↗
15Section 08, Adrian R. KrainerDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 268,338. Filing ↗
16Section 08, Ian F. SmithDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: 0. Filing ↗
17Section 08, Edward M. Kaye, M.DDEF 14A2026-04-220001193125-26-170362Section “Director Compensation”. As printed: —. Filing ↗
18Section 06, 2026 voteForm 8-K2026-06-040001193125-26-257394Item 5.07 · say-on-pay result. As reported: 72.87% (votes for as printed: 36,436,275). Filing ↗
19Section 06, 2025 voteForm 8-K2025-06-040001193125-25-134882Item 5.07 · say-on-pay result. As reported: 91.38% (votes for as printed: 30,543,514). Filing ↗
20Section 06, 2023 voteForm 8-K2023-10-260001193125-23-264160Item 5.07 · say-on-pay result. As reported: 73.69% (votes for as printed: 23,393,135). Filing ↗
21Section 01 trend, Δ column (computed)ComputedcomputedΔ = current-FY total − prior-FY total per named officer.machine: formula: Δ = FY(n) − FY(n−1)
22Section 09b board cost (computed)ComputedcomputedCash 574,138 + equity 0 + all other 1,474,242 = 2,048,380, summed across the director compensation table rows.machine: formula: Σ = 2,048,380
23Stoke Therapeutics (subject), Section 10b CEO totalDEF 14A2026-04-220001193125-26-170362CEO total compensation as printed in Stoke Therapeutics's own proxy. As printed: 27,031,655. Filing ↗machine: r2 · c31 · span 335841–335851
24Allogene Therapeutics, Section 10b CEO totalDEF 14A2026-04-300001628280-26-028948CEO total compensation as printed in Allogene Therapeutics's own proxy. As printed: 6,136,093. Filing ↗machine: r2 · c54 · span 451014–451023
25Beam Therapeutics, Section 10b CEO totalDEF 14A2026-04-170001193125-26-161512CEO total compensation as printed in Beam Therapeutics's own proxy. As printed: 5,818,525. Filing ↗machine: r2 · c29 · span 502169–502178
26Cullinan Therapeutics, Section 10b CEO totalDEF 14A2026-04-280001193125-26-183465CEO total compensation as printed in Cullinan Therapeutics's own proxy. As printed: 5,100,006. Filing ↗machine: r2 · c24 · span 475245–475254
27Poseida Therapeutics, Section 10b CEO totalDEF 14A2024-04-250000950170-24-048291CEO total compensation as printed in Poseida Therapeutics's own proxy. As printed: 3,818,018. Filing ↗machine: span 428155–428164
28Annexon, Section 10b CEO totalDEF 14A2026-04-270001140361-26-017085CEO total compensation as printed in Annexon's own proxy. As printed: 3,579,202. Filing ↗machine: r2 · c24 · span 356205–356214
29Rocket Pharmaceuticals, Section 10b CEO totalDEF 14A2026-04-060001140361-26-013335CEO total compensation as printed in Rocket Pharmaceuticals's own proxy. As printed: 3,510,241. Filing ↗machine: r2 · c24 · span 348766–348775
30Nkarta, Section 10b CEO totalDEF 14A2026-04-230001140361-26-016403CEO total compensation as printed in Nkarta's own proxy. As printed: 2,978,038. Filing ↗machine: r2 · c27 · span 344226–344235
31Fate Therapeutics, Section 10b CEO totalDEF 14A2026-04-240001193125-26-177094CEO total compensation as printed in Fate Therapeutics's own proxy. As printed: 2,248,568. Filing ↗machine: r2 · c31 · span 391551–391560
32Lineage Cell Therapeutics, Section 10b CEO totalDEF 14A2026-04-290001193125-26-191556CEO total compensation as printed in Lineage Cell Therapeutics's own proxy. As printed: 2,111,170. Filing ↗machine: span 377951–377960
334D Molecular Therapeutics, Section 10b CEO totalDEF 14A2026-04-280001140361-26-017427CEO total compensation as printed in 4D Molecular Therapeutics's own proxy. As printed: 2,051,343. Filing ↗machine: r2 · c21 · span 356185–356194
34Alector, Section 10b CEO totalDEF 14A2026-04-280001193125-26-186928CEO total compensation as printed in Alector's own proxy. As printed: 1,995,018. Filing ↗machine: span 1038665–1038674
35Caribou Biosciences, Section 10b CEO totalDEF 14A2026-04-240001619856-26-000022CEO total compensation as printed in Caribou Biosciences's own proxy. As printed: 1,840,965. Filing ↗machine: r2 · c39 · span 189876–189885
36Arcturus Therapeutics, Section 10b CEO totalDEF 14A2026-04-240001193805-26-000507CEO total compensation as printed in Arcturus Therapeutics's own proxy. As printed: 1,691,000. Filing ↗machine: t116 · r1 · c27 · span 296910–296919
37Section 10a, Beam Therapeutics reciprocityDEF 14A0001193125-26-161512Beam Therapeutics's most recent proxy was read; its disclosed peer group does not include Stoke Therapeutics. Filing ↗
38Section 10a, Lineage Cell Therapeutics reciprocityDEF 14A0001193125-26-191556Lineage Cell Therapeutics's most recent proxy was read; its disclosed peer group does not include Stoke Therapeutics. Filing ↗
39Section 10a, Alector reciprocityDEF 14A0001193125-26-186928Alector's most recent proxy was read; its disclosed peer group does not include Stoke Therapeutics. Filing ↗
40Section 10a, Arcturus Therapeutics reciprocityDEF 14A0001193805-26-000507Arcturus Therapeutics's most recent proxy was read; its disclosed peer group does not include Stoke Therapeutics. Filing ↗
41Section 10a, Allogene Therapeutics reciprocityDEF 14A0001628280-26-028948Allogene Therapeutics's most recent proxy was read; its disclosed peer group does not include Stoke Therapeutics. Filing ↗